Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Max B, Kelz"'
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114017- (2024)
Summary: The relationship between sensory stimuli and perceptions is brain-state dependent: in wakefulness, suprathreshold stimuli evoke perceptions; under anesthesia, perceptions are abolished; and during dreaming and in dissociated states, percepts
Externí odkaz:
https://doaj.org/article/9d9126ac6f5545f9a575657270097728
Autor:
Adeeti Aggarwal, Connor Brennan, Jennifer Luo, Helen Chung, Diego Contreras, Max B. Kelz, Alex Proekt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Processing sensory stimuli requires coordinated activation of neurons broadly distributed across many distant cortical sites, yet it is not clear how this coordination is accomplished in the brain. Here, the authors show that visual stimuli reliably
Externí odkaz:
https://doaj.org/article/d70d4c5214c44e8697b0d682befff323
Autor:
Michael J. Venincasa, Owen Randlett, Sureni H. Sumathipala, Richard Bindernagel, Matthew J. Stark, Qing Yan, Steven A. Sloan, Elena Buglo, Qing Cheng Meng, Florian Engert, Stephan Züchner, Max B. Kelz, Sheyum Syed, Julia E. Dallman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Delayed emergence from anesthesia was previously reported in a case study of a child with Glycine Encephalopathy. To investigate the neural basis of this delayed emergence, we developed a zebrafish glial glycine transporter (glyt1 − / −)
Externí odkaz:
https://doaj.org/article/16ccc0eb063c4163a4f45bba34befc7d
Autor:
Catherine Duclos, Danielle Nadin, Yacine Mahdid, Vijay Tarnal, Paul Picton, Giancarlo Vanini, Goodarz Golmirzaie, Ellen Janke, Michael S. Avidan, Max B. Kelz, George A. Mashour, Stefanie Blain-Moraes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Motifs are patterns of inter-connections between nodes of a network, and have been investigated as building blocks of directed networks. This study explored the re-organization of 3-node motifs during loss and recovery of consciousness. Nine
Externí odkaz:
https://doaj.org/article/cb25a4d6c7734d16b91703c625e51482
Autor:
Alexander Rokos, Bratislav Mišić, Kathleen Berkun, Catherine Duclos, Vijay Tarnal, Ellen Janke, Paul Picton, Goodarz Golmirzaie, Mathias Basner, Michael S. Avidan, Max B. Kelz, George A. Mashour, Stefanie Blain-Moraes
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
The temporal trajectories and neural mechanisms of recovery of cognitive function after a major perturbation of consciousness is of both clinical and neuroscientific interest. The purpose of the present study was to investigate network-level changes
Externí odkaz:
https://doaj.org/article/7bb16e6bb5a74e078275a79b54d40d83
Autor:
Catherine Duclos, Charlotte Maschke, Yacine Mahdid, Kathleen Berkun, Jason da Silva Castanheira, Vijay Tarnal, Paul Picton, Giancarlo Vanini, Goodarz Golmirzaie, Ellen Janke, Michael S. Avidan, Max B. Kelz, Lucrezia Liuzzi, Matthew J. Brookes, George A. Mashour, Stefanie Blain-Moraes
Publikováno v:
NeuroImage, Vol 237, Iss , Pp 118171- (2021)
The development of sophisticated computational tools to quantify changes in the brain's oscillatory dynamics across states of consciousness have included both envelope- and phase-based measures of functional connectivity (FC), but there are very few
Externí odkaz:
https://doaj.org/article/98e7a198c9c342d295070064e00cbdde
Autor:
George A Mashour, Ben JA Palanca, Mathias Basner, Duan Li, Wei Wang, Stefanie Blain-Moraes, Nan Lin, Kaitlyn Maier, Maxwell Muench, Vijay Tarnal, Giancarlo Vanini, E Andrew Ochroch, Rosemary Hogg, Marlon Schwartz, Hannah Maybrier, Randall Hardie, Ellen Janke, Goodarz Golmirzaie, Paul Picton, Andrew R McKinstry-Wu, Michael S Avidan, Max B Kelz
Publikováno v:
eLife, Vol 10 (2021)
Understanding how the brain recovers from unconsciousness can inform neurobiological theories of consciousness and guide clinical investigation. To address this question, we conducted a multicenter study of 60 healthy humans, half of whom received ge
Externí odkaz:
https://doaj.org/article/f85ef149dc0d4cb0a3e3215d99a0a484
Autor:
Sarah L. Reitz, Max B. Kelz
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The role of the hypothalamic preoptic area (POA) in arousal state regulation has been studied since Constantin von Economo first recognized its importance in the early twentieth century. Over the intervening decades, the POA has been shown to modulat
Externí odkaz:
https://doaj.org/article/77201d7a10ae44388b43c399b358fc74
Autor:
Andrew R. McKinstry-Wu, Andrzej Z. Wasilczuk, William P. Dailey, Roderic G. Eckenhoff, Max B. Kelz
Publikováno v:
The Journal of Neuroscience. 43:2338-2348
Photoaffinity ligands are best known as tools used to identify the specific binding sites of drugs to their molecular targets. However, photoaffinity ligands have the potential to further define critical neuroanatomic targets of drug action. In the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eeabb00f96dbaf20c8b591ada6b2f8c
https://doi.org/10.1523/jneurosci.1884-22.2023
https://doi.org/10.1523/jneurosci.1884-22.2023
Autor:
Andrew R McKinstry-Wu, Andrzej Z Wasilczuk, Benjamin A Harrison, Victoria M Bedell, Mathangi J Sridharan, Jayce J Breig, Michael Pack, Max B Kelz, Alexander Proekt
Publikováno v:
eLife, Vol 8 (2019)
Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here, we interrogate the
Externí odkaz:
https://doaj.org/article/4213c79618d14c70a26b18d0e1174344