SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells

Autor: Lilian M. Sluimer, Esme Bullock, Max A. K. Rätze, Lotte Enserink, Celine Overbeeke, Marten Hornsveld, Valerie G. Brunton, Patrick W. B. Derksen, Sandra Tavares

Publikováno v: Sluimer, L, Bullock, E, Ratze, M, Enserink, L, Overbeeke, C, Hornsveld, M, Brunton, V G, Derksen, P W B & Tavares, S 2023, ' SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells ', Journal of Cell Science, vol. 136, no. 3, jcs260243 . https://doi.org/10.1242/jcs.260243

High expression of the tyrosine kinase FER is an independent prognostic factor that correlates with poor survival in breast cancer patients. To investigate whether the kinase activity is essential for FER oncogenic properties, we developed an ATP ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a50db47529209457c83fae573feae8
https://www.pure.ed.ac.uk/ws/files/320926987/SKOR1_mediates_FER_kinase_dependent_invasive_growth_of_breast_cancer_cells_AAM.pdf

Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer

Autor: Max A. K. Rätze, Thijs Koorman, Thijmen Sijnesael, Blessing Bassey-Archibong, Robert van de Ven, Lotte Enserink, Daan Visser, Sridevi Jaksani, Ignacio Viciano, Elvira R. M. Bakker, François Richard, Andrew Tutt, Lynda O’Leary, Amanda Fitzpatrick, Pere Roca-Cusachs, Paul J. van Diest, Christine Desmedt, Juliet M. Daniel, Clare M. Isacke, Patrick W. B. Derksen

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Invasive lobular breast carcinoma (ILC) is characterized by proliferative indolence and long-term latency relapses. This study aimed to identify how disseminating ILC cells control the balance between quiescence and cell cycle re-entry. In the absenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d74297b9736f33f00ca5d30b6d6952e
https://pubmed.ncbi.nlm.nih.gov/35610485