Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Max, Hefti"'
Autor:
Florian Huwyler, Janina Eden, Jonas Binz, Leslie Cunningham, Richard X. Sousa Da Silva, Pierre‐Alain Clavien, Philipp Dutkowski, Mark W. Tibbitt, Max Hefti
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Biomarkers are powerful clinical diagnostics and predictors of patient outcome. However, robust measurements often require time and expensive laboratory equipment, which is insufficient to track rapid changes and limits direct use in the ope
Externí odkaz:
https://doaj.org/article/c3ebf015e27c4214bc3b0b856f6ceec3
Autor:
Mark W. Tibbitt, Leandro Mancina, Martin J. Schuler, Philipp Dutkowski, Henrik Petrowsky, Dustin Becker, Philipp Rudolf von Rohr, Michelle L. de Oliveira, Christian E. Oberkofler, Richard X Sousa Da Silva, Pierre-Alain Clavien, Matteo Mueller, Lucia Bautista Borrego, Brian Burg, Catherine Hagedorn, Dilmurodjon Eshmuminov, Achim Weber, Max Hefti
Publikováno v:
Annals of Surgery. 274:836-842
Objective The aim of this study was to maintain long-term full function and viability of partial livers perfused ex situ for sufficient duration to enable ex situ treatment, repair, and regeneration. Background Organ shortage remains the single most
Autor:
Martin J. Schuler, Dustin Becker, Matteo Mueller, Lucia Bautista Borrego, Leandro Mancina, Florian Huwyler, Jonas Binz, Catherine Hagedorn, Beatrice Schär, Erich Gygax, Miriam Weisskopf, Richard Xavier Sousa Da Silva, João Miguel Antunes Crisóstomo, Philipp Dutkowski, Philipp Rudolf von Rohr, Pierre‐Alain Clavien, Mark W. Tibbitt, Dilmurodjon Eshmuminov, Max Hefti
Publikováno v:
Artificial organsREFERENCES.
Ex situliver machine perfusion at subnormothermic/normothermic temperature isincreasingly applied in the field of transplantation to store and evaluateorgans on the machine prior transplantation. Currently, various perfusionconcepts are in clinical a
Autor:
Philipp Rudolf von Rohr, Dilmurodjon Eshmuminov, Stephanie Häusler, Max Hefti, Matteo Mueller, Dustin Becker, Bruno Stieger, Pierre-Alain Clavien, Julia Steiger, Lucia Bautista Borrego, Martin J. Schuler, Philipp Dutkowski, Catherine Hagedorn, Mark W. Tibbitt
Publikováno v:
Surgery. 169:894-902
Long-term ex situ liver perfusion may rescue injured grafts. Little is known about bile flow during long-term perfusion. We report the development of a bile stimulation protocol and motivate bile flow as a viability marker during long-term ex situ li
Autor:
Valerie Treyer, Martin W. Huellner, Max Hefti, Erika Orita, Philipp A. Kaufmann, Konstantinos Zeimpekis, Martin J. Schuler, Philipp Dutkowski, Lucia Bautista Borrego, Dilmurodjon Eshmuminov, Matteo Mueller, Dustin Becker, Pierre-Alain Clavien
Publikováno v:
Nuclear Medicine Communications. 42:826-832
PURPOSE Ex vivo liver machine perfusion is a promising option to rescue marginal liver grafts mitigating the donated organ shortage. Recently, a novel liver perfusion machine that can keep injured liver grafts alive for 1 week ex vivo was developed a
Autor:
Catherine Hagedorn, Rolf Graf, Philipp Rudolf von Rohr, Max Hefti, Lucia Bautista Borrego, Christopher H. Onder, Xavier Muller, Pierre-Alain Clavien, Dilmurodjon Eshmuminov, Martin J. Schuler, Philipp Dutkowski, Mark W. Tibbitt, Dustin Becker
Publikováno v:
IEEE Transactions on Biomedical Engineering. 67:667-678
Objective: The hepatic arterial buffer response is a well-known phenomenon in hepatic circulation, describing the response of hepatic arterial resistance to changes in portal vein flow. Several vasoactive metabolites underlying its mechanism have bee
Autor:
Pierre-Alain Clavien, Martin J. Schuler, Philipp Dutkowski, Catherine Hagedorn, Dilmurodjon Eshmuminov, Achim Weber, Lucia Bautista Borrego, Christopher H. Onder, Rolf Graf, Max Hefti, Matteo Mueller, Dustin Becker, Xavier Muller, Philipp Rudolf von Rohr
Publikováno v:
Nature Biotechnology
The ability to preserve metabolically active livers ex vivo for 1 week or more could allow repair of poor-quality livers that would otherwise be declined for transplantation. Current approaches for normothermic perfusion can preserve human livers for
Autor:
Matteo, Mueller, Max, Hefti, Dilmurodjon, Eshmuminov, Martin J, Schuler, Richard X, Sousa Da Silva, Henrik, Petrowsky, Michelle L, De Oliveira, Christian E, Oberkofler, Catherine, Hagedorn, Leandro, Mancina, Achim, Weber, Brian, Burg, Mark W, Tibbitt, Philipp, Rudolf von Rohr, Philipp, Dutkowski, Dustin, Becker, Lucia, Bautista Borrego, Pierre-Alain, Clavien
Publikováno v:
Annals of surgery. 274(5)
The aim of this study was to maintain long-term full function and viability of partial livers perfused ex situ for sufficient duration to enable ex situ treatment, repair, and regeneration.Organ shortage remains the single most important factor limit
Autor:
Mark W. Tibbitt, Philipp Rudolf von Rohr, Silvio D. Brugger, Max Hefti, Dustin Becker, Martin J. Schuler, Philipp Dutkowski, Pierre-Alain Clavien, Nicolas J. Mueller, Dilmurodjon Eshmuminov, Muhayyo Duskabilova, Catherine Hagedorn, Matteo Mueller, Lucia Bautista Borrego
Publikováno v:
Transplant Infectious Disease. 23
INTRODUCTION The use of normothermic liver machine perfusion to repair injured grafts ex situ is an emerging topic of clinical importance. However, a major concern is the possibility of microbial contamination in the absence of a fully functional imm
Autor:
Max Hefti, Martin J. Schuler, Philipp Dutkowski, Maximilian Halbe, Stephan Segerer, Pierre-Alain Clavien, Lucia Bautista Borrego, Mark W. Tibbitt, Dilmurodjon Eshmuminov, Matteo Mueller, Dustin Becker, Philipp Rudolf von Rohr, Catherine Hagedorn
Publikováno v:
Scientific Reports, 10 (1)
Scientific Reports
Scientific Reports
Long-term perfusion of liver grafts outside of the body may enable repair of poor-quality livers that are currently declined for transplantation, mitigating the global shortage of donor livers. In current ex vivo liver perfusion protocols, hyperoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4524b73e5b07301cb1d29d59df01cf93
https://www.zora.uzh.ch/id/eprint/199375/
https://www.zora.uzh.ch/id/eprint/199375/