Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Max, E Wilkinson"'
Autor:
Chris J. Frangieh, Max E. Wilkinson, Daniel Strebinger, Jonathan Strecker, Michelle L. Walsh, Guilhem Faure, Irina A. Yushenova, Rhiannon K. Macrae, Irina R. Arkhipova, Feng Zhang
Publikováno v:
Mobile DNA, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Eukaryotic retroelements are generally divided into two classes: long terminal repeat (LTR) retrotransposons and non-LTR retrotransposons. A third class of eukaryotic retroelement, the Penelope-like elements (PLEs), has been well-characteriz
Externí odkaz:
https://doaj.org/article/356462f605d44af0b6c59f8127673873
Publikováno v:
Science. 380:301-308
Non–long terminal repeat (non-LTR) retrotransposons, or long interspersed nuclear elements (LINEs), are an abundant class of eukaryotic transposons that insert into genomes by target-primed reverse transcription (TPRT). During TPRT, a target DNA se
Autor:
Jonathan Strecker, F. Esra Demircioglu, David Li, Guilhem Faure, Max E. Wilkinson, Jonathan S. Gootenberg, Omar O. Abudayyeh, Hiroshi Nishimasu, Rhiannon K. Macrae, Feng Zhang
Publikováno v:
Science
In prokaryotes, CRISPR-Cas systems provide adaptive immune responses against foreign genetic elements through RNA-guided nuclease activity. Recently, additional genes with non-nuclease functions have been found in genetic association with CRISPR syst
Autor:
Linyi Alex Gao, Max E. Wilkinson, Jonathan Strecker, Kira S. Makarova, Rhiannon K. Macrae, Eugene V. Koonin, Feng Zhang
Publikováno v:
Science
Many organisms have evolved specialized immune pattern-recognition receptors, including nucleotide-binding oligomerization domain–like receptors (NLRs) of the STAND superfamily that are ubiquitous in plants, animals, and fungi. Although the roles o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a64fcd11f1de3d57b9482c0c2cf12e
https://europepmc.org/articles/PMC10028730/
https://europepmc.org/articles/PMC10028730/
Autor:
Seiichi Hirano, Kalli Kappel, Han Altae-Tran, Guilhem Faure, Max E. Wilkinson, Soumya Kannan, F. Esra Demircioglu, Rui Yan, Momoko Shiozaki, Zhiheng Yu, Kira S. Makarova, Eugene V. Koonin, Rhiannon K. Macrae, Feng Zhang
Publikováno v:
Nature. 610(7932)
RNA-guided systems, such as CRISPR–Cas, combine programmable substrate recognition with enzymatic function, a combination that has been used advantageously to develop powerful molecular technologies1,2. Structural studies of these systems have illu
Publikováno v:
Annual Review of Biochemistry
The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades of biochemistry and genetics combined with recent structural studies of the spliceosome have produced a detailed view of the mechanism of splicing. In this review, we a
Publikováno v:
Acta Crystallogr D Struct Biol
Acta Crystallographica. Section D, Structural Biology
Acta Crystallographica. Section D, Structural Biology
A workflow to combine cryo-EM data collected at different magnification.
Recent developments have resulted in electron cryo-microscopy (cryo-EM) becoming a useful tool for the structure determination of biological macromolecules. For samples con
Recent developments have resulted in electron cryo-microscopy (cryo-EM) becoming a useful tool for the structure determination of biological macromolecules. For samples con
Publikováno v:
Science
A human P spliceosome structure Splicing of some pre–messenger RNAs could be regulated by cell type–specific splicing factors. Fica et al. describe the cryo–electron microscopy structure of the human postcatalytic (P) spliceosome. Surprisingly,
Autor:
Fabio, Villani, Riccardo, Civico, Stefano, Pucci, Luca, Pizzimenti, Rosa, Nappi, Paolo Marco De Martini, Agosta, Fabrizio, Giuliana, Alessio, Lucilla, Alfonsi, Marco, Amanti, Amoroso, S., Aringoli, Domenico, Auciello, E., Raffaele, Azzaro, Stéphane, Baize, Bello, S., Lucilla, Benedetti, Antonella, Bertagnini, Giulia, Binda, Bisson, M., Anna Maria Blumetti, Bonadeo, L., Paolo, Boncio, Philipp, Bornemann, Branca, S., Braun, Thomas R., Francesco, Brozzetti, Carlo Alberto Brunori, Pierfrancesco, Burrato, Marco, Caciagli, Campobasso, C., Carafa, Michele M. C., Francesca Romana Cinti, Domenico, Cirillo, Valerio, Comerci, Luigi, Cucci, Riccardo De Ritis, Graziella, Deiana, Paola Del Carlo, Luis Mercader del Río, Alain, Delorme, Pio Di Manna, Deborah Di Naccio, Laurel, Falconi, Emanuela, Falcucci, Farabollini, Piero, Joanna Faure Walker, Ferrarini, F., Ferrario, M. F., Matthieu, Ferry, Nathalie, Feuillet, Jules, Fleury, Umberto, Fracassi, Chiara, Frigerio, Frank, Galluzzo, Gambillara, R., Gaetano, Gaudiosi, Hollis, Goodall, Gori, S, Gregory, Laura C., Luca, Guerrieri, Salomon, Hailemikael, James, Hollingsworth, Francesca, Iezzi, Invernizzi, Maria Chiara, Jablonska, Danica, Evouna, Jacques, Hervé, Jomard, Vanja, Kastelic, Yann, Klinger, Giusy, Lavecchia, Frederique, Leclerc, Francesca, Liberi, Arianna, Lisi, Franz, Livio, Lorenzo Lo Sardo, Malet, J. P., Maria Teresa Mariucci, Materazzi, Marco, Maubant, L., Francesco, Mazzarini, Mccaffrey, K. J. W., Michetti, Alessandro Maria, Mildon, Z. K., Paola, Montone, Marco, Moro, Rosella, Nave, Marielle, Odin, Bruno, Pace, Sherman, Paggi, Nicola Mauro Pagliuca, Pambianchi, Gilberto, Daniela, Pantosti, Antonio, Patera, Eugénie, Pérouse, Giuseppe, Pezzo, Luigi, Piccardi, Pierantoni, Pietro Paolo, Maurizio, Pignone, Pinzi, S., Pistolesi, Eugenio, Point, J., Pousse, L., Alessia, Pozzi, Marco, Proposito, Puglisi, C., Puliti, I., Tullio, Ricci, Licia, Ripamonti, Magali, Rizza, Roberts, Gerald P., Roncoroni, M., Vincenzo, Sapia, Michele, Saroli, Alessandra, Sciarra, Oona, Scotti, Grzegorz, Skupinski, Smedile, A., Anne, Socquet, Gabriele, Tarabusi, Simone, Tarquini, Terrana, S., Jim, Tesson, Tondi, Emanuele, Alessio, Valentini, Roberta, Vallone, van der Woerd, J., Paola, Vannoli, Venuti, A., Eutizio, Vittori, Volatili, Tiziano, Wedmore, L. N. J., Max, E Wilkinson, Melba, Zambrano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3707::da40eef2b113cc170b7f712c3ef1f23e
http://hdl.handle.net/11581/434964
http://hdl.handle.net/11581/434964
Publikováno v:
Molecular Cell
Summary The ATPase Prp16 governs equilibrium between the branching (B∗/C) and exon ligation (C∗/P) conformations of the spliceosome. Here, we present the electron cryomicroscopy reconstruction of the Saccharomyces cerevisiae C-complex spliceosome