Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets

Autor: van der Meulen, T, Mawla, AM, DiGruccio, MR, Adams, MW, Nies, V, Dólleman, S, Liu, S, Ackermann, AM, Cáceres, E, Hunter, AE, Kaestner, KH, Donaldson, CJ, Huising, MO

Publikováno v: van der Meulen, T; Mawla, AM; DiGruccio, MR; Adams, MW; Nies, V; Dólleman, S; et al.(2017). Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets. Cell Metabolism, 25(4), 911-926.e6. doi: 10.1016/j.cmet.2017.03.017. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/85r6t1w6

© 2017 Postnatal maintenance or regeneration of pancreatic beta cells is considered to occur exclusively via the replication of existing beta cells, but clinically meaningful restoration of human beta cell mass by proliferation has never been achiev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a755f7b4d8dc916b8a60539f5ed89cb5
http://www.escholarship.org/uc/item/85r6t1w6

Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning.

Autor: Roy G, Syed R, Lazaro O, Robertson S, McCabe SD, Rodriguez D, Mawla AM, Johnson TS, Kalwat MA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 23. Date of Electronic Publication: 2024 Jan 23.

The efficacy of Nile tilapia skin xenograft for treating superficial partial-thickness burn versus the standard of care: a meta-analysis of published trials.

Autor: Cadri S; University of Medicine and Pharmacy, Grigore T. Popa, Iasi, Romania. cadrishirin@gmail.com.; Medical Research Group of Romania, Negida Academy, Arlington, MA, USA. cadrishirin@gmail.com., Elrosasy A; Medical Research Group of Egypt, Negida Academy, Arlington, MA, USA.; Faculty of Medicine, Cairo University, Cairo, Egypt., Al Mawla AM; Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.; Medical Research Group of Jordan, Negida Academy, Arlington, MA, USA., Albakri K; Medical Research Group of Jordan, Negida Academy, Arlington, MA, USA.; Faculty of Medicine, The Hashemite University, Zarqa, Jordan., Abdelwahab OA; Medical Research Group of Egypt, Negida Academy, Arlington, MA, USA.; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Soliman A; Medical Research Group of Egypt, Negida Academy, Arlington, MA, USA.; Faculty of Medicine, Mansoura University, Mansoura, Egypt., Jaradat B; Medical Research Group of Jordan, Negida Academy, Arlington, MA, USA.; Faculty of Medicine, The Hashemite University, Zarqa, Jordan., Cadri N; University of Medicine and Pharmacy, Grigore T. Popa, Iasi, Romania.; Medical Research Group of Romania, Negida Academy, Arlington, MA, USA., Alabdallat YJ; Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.; Medical Research Group of Jordan, Negida Academy, Arlington, MA, USA., Negida A; Medical Research Group of Egypt, Negida Academy, Arlington, MA, USA.; Virginia Commonwealth University, Richmond, VA, USA.

Publikováno v: Archives of dermatological research [Arch Dermatol Res] 2023 Dec 11; Vol. 316 (1), pp. 33. Date of Electronic Publication: 2023 Dec 11.

Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity.

Autor: Cha J; Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Tong X; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Walker EM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Dahan T; Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel., Cochrane VA; Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Ashe S; Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Russell R; Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Osipovich AB; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Mawla AM; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, Davis, California, USA., Guo M; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Liu JH; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Loyd ZA; Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Huising MO; Department of Neurobiology, Physiology & Behavior, College of Biological Sciences, University of California, Davis, Davis, California, USA., Magnuson MA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Hebrok M; Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA., Dor Y; Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel., Stein R; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.

Publikováno v: JCI insight [JCI Insight] 2023 Aug 22; Vol. 8 (16). Date of Electronic Publication: 2023 Aug 22.

A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.

Autor: Rubio-Navarro A; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Excellence Research Unit 'Modeling Nature' (MNat), CTS-963-Center of Biomedical Research (CIBM), University of Granada, Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), University Hospitals of Granada-University of Granada, Granada, Spain., Gómez-Banoy N; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Stoll L; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Dündar F; Department of Physiology and Biophysics, Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, USA., Mawla AM; Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, CA, USA., Ma L; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Cortada E; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Zumbo P; Department of Physiology and Biophysics, Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, USA., Li A; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Reiterer M; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Montoya-Oviedo N; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Lipids and Diabetes Laboratory, Department of Physiological Sciences, Faculty of Medicine, National University of Colombia, Bogotá, Colombia., Homan EA; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Imai N; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan., Gilani A; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Liu C; Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Naji A; Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Yang B; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Chong ACN; Department of Surgery, Weill Cornell Medicine, New York, NY, USA., Cohen DE; Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY, USA., Cao J; Cardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA., Pitt GS; Cardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA., Huising MO; Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, CA, USA.; Department of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, CA, USA., Betel D; Department of Physiology and Biophysics, Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Division of Hematology and Medical Oncology, Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY, USA., Lo JC; Weill Center for Metabolic Health, Cardiovascular Research Institute, Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA. jlo@med.cornell.edu.

Publikováno v: Nature cell biology [Nat Cell Biol] 2023 Apr; Vol. 25 (4), pp. 565-578. Date of Electronic Publication: 2023 Mar 16.