Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mawj Mandwie"'
Autor:
Mawj Mandwie, Jordan A Piper, Catherine A Gorrie, Kevin A Keay, Giuseppe Musumeci, Ghaith Al-Badri, Alessandro Castorina
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 378-385 (2022)
Evidence suggests that rapid changes to supporting glia may predispose individuals with spinal cord injury (SCI) to such comorbidities. Here, we interrogated the expression of astrocyte- and microglial-specific markers glial fibrillary acidic protein
Externí odkaz:
https://doaj.org/article/e23dc9e10b62425eac8d02f50d6bbe15
Autor:
Jayden Lee, Sarah Thomas Broome, Margo Iris Jansen, Mawj Mandwie, Grant J. Logan, Rubina Marzagalli, Giuseppe Musumeci, Alessandro Castorina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11118 (2023)
Neuropsychiatric systemic lupus erythematosus (NPSLE) is one of the most common and severe manifestations of lupus; however, its pathogenesis is still poorly understood. While there is sparse evidence suggesting that the ongoing autoimmunity may trig
Externí odkaz:
https://doaj.org/article/2e9dddc352c04ce0adbcc59cdd864b39
Autor:
Mawj Mandwie, Jocelyn Karunia, Aram Niaz, Kevin A. Keay, Giuseppe Musumeci, Claire Rennie, Kristine McGrath, Ghaith Al-Badri, Alessandro Castorina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13660 (2021)
High-fat diet (HFD)-induced comorbid cognitive and behavioural impairments are thought to be the result of persistent low-grade neuroinflammation. Metformin, a first-line medication for the treatment of type-2 diabetes, seems to ameliorate these como
Externí odkaz:
https://doaj.org/article/3c7dd9a5363d482a987f45ab8482090a
Autor:
Jocelyn Karunia, Aram Niaz, Mawj Mandwie, Sarah Thomas Broome, Kevin A. Keay, James A. Waschek, Ghaith Al-Badri, Alessandro Castorina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10947 (2021)
Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are two structurally related immunosuppressive peptides. However, the underlying mechanisms through which these peptides regulate microglial activity a
Externí odkaz:
https://doaj.org/article/7e7ecb064d294544bf917f9633491e98
Autor:
Castorina, Jayden Lee, Sarah Thomas Broome, Margo Iris Jansen, Mawj Mandwie, Grant J. Logan, Rubina Marzagalli, Giuseppe Musumeci, Alessandro
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 11118
Neuropsychiatric systemic lupus erythematosus (NPSLE) is one of the most common and severe manifestations of lupus; however, its pathogenesis is still poorly understood. While there is sparse evidence suggesting that the ongoing autoimmunity may trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e651ea5a98d581397bf13314e43c7b9b
Autor:
Grant J. Logan, Mario Mietzsch, Neeta Khandekar, Arlene D’Silva, Daniel Anderson, Mawj Mandwie, Jane Hsi, Austin R. Nelson, Paul Chipman, Jennifer Jackson, Peter Schofield, Daniel Christ, Christopher C. Goodnow, Joanne H. Reed, Michelle A. Farrar, Robert McKenna, Ian E. Alexander
Publikováno v:
Molecular Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e2ebae53db06f725e5eceb4546372bc
https://doi.org/10.1016/j.ymthe.2023.03.032
https://doi.org/10.1016/j.ymthe.2023.03.032
Autor:
Amina Ahmad, Mawj Mandwie, Kim M. O'Sullivan, Christine Smyth, Jarrod York, Helen Doyle, Stephen R. Holdsworth, Matthew C. Pickering, Peter J. Lachmann, Ian E. Alexander, Grant J. Logan
Publikováno v:
Human Gene Therapy. 33:560-571
Adeno-associated virus (AAV) vectors are proving to be clinically transformative tools in the treatment of monogenic genetic disease. Rapid ongoing development of this technology promises to not only increase the number of monogenic disorders amenabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dadd56aaeb42d64dc86dfc050ab4cd
https://doi.org/10.1089/hum.2021.264
https://doi.org/10.1089/hum.2021.264
Autor:
Alessandro Castorina, Kevin A. Keay, Jordan A Piper, Giuseppe Musumeci, Ghaith Al-Badri, Mawj Mandwie, Catherine A. Gorrie
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 378-385 (2022)
Neural Regeneration Research
Neural Regeneration Research
Spinal cord injury (SCI) is a devastating condition often associated with sleep disorders, mood change and depression. Evidence suggests that rapid changes to supporting glia may predispose individuals with SCI to such comorbidities. Here, we interro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ef82a98d605895f6cd70fdab4c0993
http://hdl.handle.net/20.500.11769/510247
http://hdl.handle.net/20.500.11769/510247
Autor:
Helen Doyle, Mawj Mandwie, Peter J. Lachmann, Talat H. Malik, Ian E. Alexander, Matthew C. Pickering, Amina Ahmad, Christine M. Smyth, Grant J Logan, Anna K. Dreismann
Publikováno v:
Human Gene Therapy.
The complement system is a key component of innate immunity, but impaired regulation influences disease susceptibility, including age-related macular degeneration and some kidney diseases. While complete complement inhibition has been used successful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77551bbc36e282ee491dfaf4ab15c440
https://doi.org/10.1089/hum.2021.022
https://doi.org/10.1089/hum.2021.022
Autor:
Ian E. Alexander, E Christina Hiemeyer, Mawj Mandwie, Linda B. Moran, Alyssa C. Gilmore, Talat H. Malik, Grant J Logan, Hannah J. Lomax-Browne, Kevin J. Marchbank, Allan Bradley, Amina Ahmad, Matthew C. Pickering, Katharina Boroviak, H. Terence Cook, Deborah P. Lavin, Daniel P. Gitterman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The complement system is integral to innate immunity and host defense. However, inappropriate activation causes host tissue damage and disease. In health, this is prevented by a complex protein network that includes the factor H proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eabe5fe4d08e90610f39cce363a90ee
http://europepmc.org/articles/PMC8020653
http://europepmc.org/articles/PMC8020653