Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Maurya IK"'
1
Akademický článek
Synthesis and mechanistic study of Aβ 42 C-terminus domain derived tetrapeptides that inhibit Alzheimer's Aβ-aggregation-induced neurotoxicity.
Autor: Sehra N; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Parmar R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Maurya IK; Center of Infectious Disease, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Nov 01; Vol. 112, pp. 129929. Date of Electronic Publication: 2024 Aug 14.
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2
Akademický článek
Synthesis and mechanistic study of ultrashort peptides that inhibits Alzheimer's Aβ-aggregation-induced neurotoxicity.
Autor: Sehra N; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Parmar R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Maurya IK; Center of Infectious Disease, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Mar; Vol. 144, pp. 107159. Date of Electronic Publication: 2024 Jan 29.
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3
Akademický článek
Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.
Autor: Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Digwal CS; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India., Neshat N; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in., Kamal A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India; Birla Institute of Technology & Science (BITS), Pilani Hyderabad Campus, Hyderabad, Telangana, 500078, India. Electronic address: ahmedkamal@iict.res.in.
Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Jul; Vol. 136, pp. 106538. Date of Electronic Publication: 2023 Apr 13.
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4
Akademický článek
Synthetic amino acids-based short amphipathic peptides exhibit antifungal activity by targeting cell membrane disruption.
Autor: Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India., Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India., Rudramurthy SM; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Singh S; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India.; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sahibzada Ajit Singh Nagar, Punjab, India.
Publikováno v: Drug development research [Drug Dev Res] 2023 May; Vol. 84 (3), pp. 514-526. Date of Electronic Publication: 2023 Feb 09.
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5
Akademický článek
Anticryptococcal activity and mechanistic studies of short amphipathic peptides.
Autor: Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India., Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India., Maurya IK; Center for Infectious Diseases, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India., Rudramurthy SM; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab, India., Singh S; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India.; Center for Infectious Diseases, National Institute of Pharmaceutical Education and Research, Nagar, Punjab, India.
Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Apr; Vol. 356 (4), pp. e2200576. Date of Electronic Publication: 2023 Jan 02.
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6
Akademický článek
Synthetic amino acids-derived peptides target Cryptococcus neoformans by inducing cell membrane disruption.
Autor: Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Sharma KK; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Singh S; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India., Rudramurthy SM; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Jan; Vol. 130, pp. 106252. Date of Electronic Publication: 2022 Nov 05.
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7
Akademický článek
Ring-Modified Histidine-Containing Cationic Short Peptides Exhibit Anticryptococcal Activity by Cellular Disruption.
Autor: Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India., Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India., Singh S; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160 012, India., Rudramurthy SM; Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160 012, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar 160 062, Punjab, India.
Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 22; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 22.
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8
Akademický článek
Antifungal evaluation and mechanistic investigations of membrane active short synthetic peptides-based amphiphiles.
Autor: Sharma K; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Maurya IK; Center for Infectious Diseases, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Rudramurthy SM; Department of Medicinal Microbiology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India., Singh S; Department of Medicinal Microbiology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab 160 062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: Bioorganic chemistry [Bioorg Chem] 2022 Oct; Vol. 127, pp. 106002. Date of Electronic Publication: 2022 Jul 04.
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9
Akademický článek
Modified histidine containing amphipathic ultrashort antifungal peptide, His[2-p-(n-butyl)phenyl]-Trp-Arg-OMe exhibits potent anticryptococcal activity.
Autor: Sharma KK; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Ravi R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Maurya IK; Department of Microbial Technology, Panjab University, Sector 25, Chandigarh 160 014, India., Kapadia A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India., Khan SI; National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar 160 062, Punjab India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar 160 062, Punjab India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2021 Nov 05; Vol. 223, pp. 113635. Date of Electronic Publication: 2021 Jun 12.
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10
Akademický článek
Structural and mechanistic insights into the inhibition of amyloid-β aggregation by Aβ 39-42 fragment derived synthetic peptides.
Autor: Kapadia A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab, 160 062, India., Sharma KK; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab, 160 062, India., Maurya IK; Department of Microbial Biotechnology, Punjab University, Sector 25, Chandigarh, 160 014, India., Singh V; Post Graduate Institute of Medical Education and Research, Sector 11, Chandigarh, 160 014, India., Khullar M; Post Graduate Institute of Medical Education and Research, Sector 11, Chandigarh, 160 014, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S Nagar, Punjab, 160 062, India. Electronic address: rahuljain@niper.ac.in.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2021 Feb 15; Vol. 212, pp. 113126. Date of Electronic Publication: 2020 Dec 28.
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