Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mauro de Meira Leite"'
Autor:
Maria Alice Freitas Queiroz, Wandrey Roberto dos Santos Brito, Keise Adrielle Santos Pereira, Leonn Mendes Soares Pereira, Ednelza da Silva Graça Amoras, Sandra Souza Lima, Erika Ferreira dos Santos, Flávia Póvoa da Costa, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Giselle Maria Rachid Viana, Tânia do Socorro Souza Chaves, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Juliana Abreu Lima Nunes, Iran Barros Costa, Izaura Maria Vieira Cayres-Vallinoto, Igor Brasil-Costa, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The cGAS-STING pathway appears to contribute to dysregulated inflammation during coronavirus disease 2019 (COVID-19); however, inflammatory factors related to long COVID are still being investigated. In the present study, we evaluated the as
Externí odkaz:
https://doaj.org/article/e6c8d11d0532469cb353e5e2332e0034
Autor:
Kevin Matheus Lima de Sarges, Flávia Póvoa da Costa, Erika Ferreira dos Santos, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Adriana de Oliveira Lameira Veríssimo, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Mauro de Meira Leite, Maria Karoliny da Silva Torres, Christiane Bentes da Silva, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Daniele Freitas Henriques, Izaura Maria Vieira Cayres Vallinoto, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos
Publikováno v:
Viruses, Vol 16, Iss 4, p 650 (2024)
Tumor necrosis factor (TNF) and interferon-gamma (IFNγ) are important inflammatory mediators in the development of cytokine storm syndrome (CSS). Single nucleotide polymorphisms (SNPs) regulate the expression of these cytokines, making host genetics
Externí odkaz:
https://doaj.org/article/472bbf52db92457eb2b8c4b988fbda85
Autor:
Maria Alice Freitas Queiroz, Angélica Menezes Santiago, Wandrey Roberto dos Santos Brito, Keise Adrielle Santos Pereira, William Botelho de Brito, Maria Karoliny da Silva Torres, Jeferson da Costa Lopes, Erika Ferreira dos Santos, Flávia Póvoa da Costa, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Giselle Maria Rachid Viana, Tânia do Socorro Souza Chaves, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro dos Santos, Juliana Abreu Lima Nunes, Iran Barros Costa, Ednelza da Silva Graça Amoras, Sandra Souza Lima, Izaura Maria Vieira Cayres-Vallinoto, Igor Brasil-Costa, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMannose-binding lectin (MBL) promotes opsonization, favoring phagocytosis and activation of the complement system in response to different microorganisms, and may influence the synthesis of inflammatory cytokines. This study investigated
Externí odkaz:
https://doaj.org/article/9eb7f27cc2f3400b8af118e61c11f094
Autor:
Maria Alice Freitas Queiroz, Pablo Fabiano Moura das Neves, Sandra Souza Lima, Jeferson da Costa Lopes, Maria Karoliny da Silva Torres, Izaura Maria Vieira Cayres Vallinoto, Carlos David Araújo Bichara, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Maria de Nazaré do Socorro de Almeida Viana, Fabíola Brasil Barbosa Rodrigues, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Clea Nazaré Carneiro Bichara, Ana Virgínia Soares van den Berg, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro dos Santos, Juliana Abreu Lima Nunes, Iran Barros Costa, Giselle Maria Rachid Viana, Francisca Regina Oliveira Carneiro, Vera Regina da Cunha Menezes Palacios, Juarez Antonio Simões Quaresma, Igor Brasil-Costa, Eduardo José Melo dos Santos, Luiz Fábio Magno Falcão, Antonio Carlos Rosário Vallinoto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The duration and severity of COVID-19 are related to age, comorbidities, and cytokine synthesis. This study evaluated the impact of these factors on patients with clinical presentations of COVID-19 in a Brazilian cohort. A total of 317 patients diagn
Externí odkaz:
https://doaj.org/article/80365dfa0442473586b2d9db46895d5c
Autor:
Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Maria de Nazaré do Socorro de Almeida Viana, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Igor Brasil Costa, Juliana Abreu Lima Nunes, Iran Barros Costa, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Sandra Souza Lima, Jeferson da Costa Lopes, Maria Karoliny da Silva Torres, Izaura Maria Vieira Cayres Vallinoto, Carlos David Araújo Bichara, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos
Publikováno v:
Viruses, Vol 15, Iss 5, p 1197 (2023)
Interleukin-6 has been recognized as a major role player in COVID-19 severity, being an important regulator of the cytokine storm. Hence, the evaluation of the influence of polymorphisms in key genes of the IL-6 pathway, namely IL6, IL6R, and IL6ST,
Externí odkaz:
https://doaj.org/article/9d3ba056670a4711b3c0fc48df07d3e6
Autor:
Rosilene da Silva, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Flávia Póvoa da Costa, Erika Ferreira dos Santos, Fabíola Brasil Barbosa Rodrigues, Maria de Nazaré do Socorro de Almeida Viana, Mauro de Meira Leite, Andréa Luciana Soares da Silva, Mioni Thieli Magalhães de Brito, Maria Karoliny da Silva Torres, Maria Alice Freitas Queiroz, Izaura Maria Vieira Cayres Vallinoto, Daniele Freitas Henriques, Carla Pinheiro dos Santos, Giselle Maria Rachid Viana, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Antonio Carlos Rosário Vallinoto, Eduardo José Melo dos Santos
Publikováno v:
Viruses, Vol 15, Iss 4, p 885 (2023)
Aiming to evaluate the role of ten functional polymorphisms in long COVID, involved in major inflammatory, immune response and thrombophilia pathways, a cross-sectional sample composed of 199 long COVID (LC) patients and a cohort composed of 79 COVID
Externí odkaz:
https://doaj.org/article/9a19e2486c4b4e92b6a39d41886a0518
Autor:
Sinei Ramos Soares, Maria Karoliny da Silva Torres, Sandra Souza Lima, Kevin Matheus Lima de Sarges, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flávia Póvoa da Costa, Marcos Henrique Damasceno Cantanhede, Rosilene da Silva, Adriana de Oliveira Lameira Veríssimo, Izaura Maria Vieira Cayres Vallinoto, Rosimar Neris Martins Feitosa, Juarez Antônio Simões Quaresma, Tânia do Socorro Souza Chaves, Giselle Maria Rachid Viana, Luiz Fábio Magno Falcão, Eduardo José Melo dos Santos, Antonio Carlos Rosário Vallinoto, Andréa Nazaré Monteiro Rangel da Silva
Publikováno v:
Viruses, Vol 15, Iss 4, p 898 (2023)
The first case of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in Brazil was diagnosed on February 26, 2020. Due to the important epidemiological impact of COVID-19, the present study ai
Externí odkaz:
https://doaj.org/article/d94907565af34f9ca3ca910ecb21ae09
Autor:
Marcos Henrique Damasceno Cantanhede, Kevin Matheus de Lima Sarges, Mauro de Meira Leite, Fábio Miyajima, Eduardo José Melo dos Santos
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 26, Iss , Pp 102082- (2022)
Introdução/Objetivos: O SARS-CoV-2 (Síndrome Respiratória Aguda Grave Coronavírus 2, do inglês, Severe Acute Respiratory Syndrome Coronavirus) é o responsável por causar a Doença do Coronavírus 2019, do inglês Coronavirus Disease 2019 ou C
Externí odkaz:
https://doaj.org/article/aa64f1e62198457aac4816699e623959
Autor:
Fabíola Brasil Barbosa Rodrigues, Rosilene da Silva, Erika Ferreira dos Santos, Mioni Thieli Figueiredo Magalhães de Brito, Andréa Luciana Soares da Silva, Mauro de Meira Leite, Flavia Póvoa da Costa, Maria de Nazaré do Socorro de Almeida Viana, Kevin Matheus Lima de Sarges, Marcos Henrique Damasceno Cantanhede, Adriana de Oliveira Lameira Veríssimo, Mayara da Silva Carvalho, Daniele Freitas Henriques, Carla Pinheiro da Silva, Juliana Abreu Lima Nunes, Iran Barros Costa, Giselle Maria Rachid Viana, Maria Alice Freitas Queiroz, Sandra Souza Lima, Jeferson da Costa Lopes, Maria Karoliny da Silva Torres, Carlos David Araújo Bichara, Izaura Maria Vieira Cayres Vallinoto, Antonio Carlos Rosario Vallinoto, Eduardo José Melo dos Santos
Interleukin-6 have been recognized as a major role player in COVID-19 severity, being an important regulator of cytokine storm. Hence, the evaluation of the influence of polymorphisms in key genes of IL-6 pathway, namely IL6, IL6R and IL6ST, may prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da759bad5207fc2aa0180ea3d58d813e
https://doi.org/10.1101/2022.09.21.508870
https://doi.org/10.1101/2022.09.21.508870
Autor:
Faviel F. Gonzalez-Galarza, Mauro de Meira Leite, Bruno Conde Costa da Silva, Eduardo José Melo dos Santos, Derek Middleton
Publikováno v:
Human Immunology
Immunorelevant genes are among the most probable modulators of coronavirus disease 2019 (COVID-19) progression and prognosis. However, in the few months of the pandemic, data generated on host genetics has been scarce. The present study retrieved dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903be4b801e24e049e690ebd52dd6e9a
https://doi.org/10.1016/j.humimm.2021.01.008
https://doi.org/10.1016/j.humimm.2021.01.008