Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mauro Sbroggio"'
Autor:
María Castejón-Griñán, Eliene Albers, Lucía Simón-Carrasco, Paula Aguilera, Mauro Sbroggio, David Pladevall-Morera, Andreas Ingham, Ernest Lim, Alba Guillen-Benitez, Elena Pietrini, Michael Lisby, Ian D. Hickson, Andres J. Lopez-Contreras
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Plk1-interacting checkpoint helicase (PICH) is a DNA translocase involved in resolving ultrafine anaphase DNA bridges and, therefore, is important to safeguard chromosome segregation and stability. PICH is overexpressed in various human canc
Externí odkaz:
https://doaj.org/article/7de1b99b4f8b44b9b87279d3104a6ec4
Autor:
Matteo Sorge, Giulia Savoré, Andrea Gallo, Davide Acquarone, Mauro Sbroggiò, Silvia Velasco, Federica Zamporlini, Saveria Femminò, Enrico Moiso, Giampaolo Morciano, Elisa Balmas, Andrea Raimondi, Gabrielle Nattenberg, Rachele Stefania, Carlo Tacchetti, Angela Maria Rizzo, Paola Corsetto, Alessandra Ghigo, Emilia Turco, Fiorella Altruda, Lorenzo Silengo, Paolo Pinton, Nadia Raffaelli, Nathan J Sniadecki, Claudia Penna, Pasquale Pagliaro, Emilio Hirsch, Chiara Riganti, Guido Tarone, Alessandro Bertero, Mara Brancaccio
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2450-2484 (2024)
Abstract Defining the molecular mechanisms underlying cardiac resilience is crucial to find effective approaches to protect the heart. A physiologic level of ROS is produced in the heart by fatty acid oxidation, but stressful events can boost ROS and
Externí odkaz:
https://doaj.org/article/fbbe12027f6940b5871e50bcfc957a2f
Autor:
Marcos Siguero-Álvarez, Alejandro Salguero-Jiménez, Joaquim Grego-Bessa, Jorge de la Barrera, Donal MacGrogan, Belén Prados, Fernando Sánchez-Sáez, Rebeca Piñeiro-Sabarís, Natalia Felipe-Medina, Carlos Torroja, Manuel José Gómez, María Sabater-Molina, Rubén Escribá, Ivonne Richaud-Patin, Olalla Iglesias-García, Mauro Sbroggio, Sergio Callejas, Declan P. O’Regan, Kathryn A. McGurk, Ana Dopazo, Giovanna Giovinazzo, Borja Ibañez, Lorenzo Monserrat, José María Pérez-Pomares, Fátima Sánchez-Cabo, Alberto M. Pendas, Angel Raya, Juan R. Gimeno-Blanes, José Luis de la Pompa
The complex genetics underlying human cardiac disease is evidenced by its heterogenous manifestation, multigenic basis, and sporadic occurrence. These features have hampered disease modeling and mechanistic understanding. Here, we show that 2 structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c9d5c2f3da4e9446d77a979ec3f9f2
http://hdl.handle.net/2445/193600
http://hdl.handle.net/2445/193600
Autor:
Eliene Albers, Mauro Sbroggiò, David Pladevall-Morera, Anna H. Bizard, Alexandra Avram, Patricia Gonzalez, Javier Martin-Gonzalez, Ian D. Hickson, Andres J. Lopez-Contreras
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3274-3284 (2018)
Summary: PICH is a DNA translocase necessary for the resolution of ultrafine anaphase DNA bridges and to ensure the fidelity of chromosomal segregation. Here, we report the generation of an animal model deficient for PICH that allowed us to investiga
Externí odkaz:
https://doaj.org/article/149a3d169b514d959965752a637b3358