Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mauro Ponti"'
Autor:
Andrew S. Thompson, Brigid M Hoey, Mark D. Berardini, John A. Hartley, David E. Thurston, Mauro Ponti, Neil W. Gibson, John Butler
Publikováno v:
Biochemistry. 30:11719-11724
Several bifunctional alkylating agents of the aziridinylbenzoquinone class have been evaluated as potential antitumor agents. 3,6-Bis[(2-hydroxyethyl)amino]-2,5- diaziridinyl-1,4-benzoquinone (BZQ), 2,5-diaziridinyl-1,4-benzoquinone (DZQ), 3,6-bis(ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef9805124c67d8db4f798622721399d
https://doi.org/10.1021/bi00114a016
https://doi.org/10.1021/bi00114a016
Publikováno v:
British Journal of Cancer
Members of the homologous series of alkanediol dimethanesulphonates of general formula H3C.SO2O.(CH2)n.O.SO2.CH3 have been tested for their ability to produce DNA interstrand crosslinking and DNA sequence selectivity of guanine-N7 alkylation. In a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65edf56eadbe72b4b1f50d706360fb1f
https://doi.org/10.1038/bjc.1991.166
https://doi.org/10.1038/bjc.1991.166
Publikováno v:
Nucleic Acids Research. 19:2929-2933
A polymerase stop assay has been developed to determine the DNA nucleotide sequence specificity of covalent modification by antineoplastic agents using the thermostable DNA polymerase from Thermus aquaticus and synthetic labelled primers. The product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c02674c7f9b0007e9cf2948e03e7ef0
https://doi.org/10.1093/nar/19.11.2929
https://doi.org/10.1093/nar/19.11.2929
Publikováno v:
British Journal of Cancer
The DNA damage and the sequence specificity of guanine-N7 alkylation produced by the novel, positively charged, antineoplastic agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate) and its uncharged tertiary amine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e72433bc8e34868912fab3ae8670ff
https://doi.org/10.1038/bjc.1990.53
https://doi.org/10.1038/bjc.1990.53
Publikováno v:
Life sciences. 53(20)
The present paper describes a new image processing method for automatic quantitative analysis of autoradiographic band films. It was developed in a specific image analysis environment (IBAS 2.0), but the algorithms and methods can be utilized elsewhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c65762e86f9549fe26e76a6a4480716
https://pubmed.ncbi.nlm.nih.gov/8412515
https://pubmed.ncbi.nlm.nih.gov/8412515
Publikováno v:
Scopus-Elsevier
This study was designed to evaluate the effects of vital dye Hoechst 33342 (HO 33342), at concentrations used to obtain a good DNA histogram resolution, on DNA integrity, cell growth, and cell-cycle phase distribution of L1210 cells. HO 33342 exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8d28e51f074bb5f4d7604660965667
https://doi.org/10.1002/cyto.990090102
https://doi.org/10.1002/cyto.990090102
Autor:
Nicola Mongelli, Roberto Mantovani, Sergio Ottolenghi, Mauro Ponti, Maurizio D'Incalci, Massimo Broggini
Publikováno v:
Nucleic acids research. 17(3)
We investigated the effects of the antiviral agent distamycin A and of a distamycin derivative (FCE 24517) which possesses antineoplastic activity on the binding of some regulatory proteins to DNA. Both compounds inhibited the binding to DNA of the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76b8d950a8913c4fe60dc14f42a63c4
https://pubmed.ncbi.nlm.nih.gov/2922260
https://pubmed.ncbi.nlm.nih.gov/2922260