Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mauro Paolucci"'
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Figure S2 - PDF file 456K, Time-lapse imaging of A375 cells treated with NMS-E973
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f283c674905df024deea1ce236ca7aa
https://doi.org/10.1158/1078-0432.22451829.v1
https://doi.org/10.1158/1078-0432.22451829.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Table S1 - PDF file 94K, Antiproliferative activity of NMS-E973
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d89fb90cbe5dad008cd241246f1ef48
https://doi.org/10.1158/1078-0432.22451817.v1
https://doi.org/10.1158/1078-0432.22451817.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Purpose: Recent developments of second generation Hsp90 inhibitors suggested a potential for development of this class of molecules also in tumors that have become resistant to molecular targeted agents. Disease progression is often due to brain meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0947fcab05687d15962c1dd2f2c4d7a7
https://doi.org/10.1158/1078-0432.c.6522303.v1
https://doi.org/10.1158/1078-0432.c.6522303.v1
Autor:
Antonella Isacchi, Sergio Mantegani, Arturo Galvani, Enrico Pesenti, Eduard Felder, Daniele Donati, Fabio Zuccotto, Carlo Visco, Barbara Valsasina, Francesco Sola, Micaela Russo, Paolo Polucci, Mauro Paolucci, Marco Guanci, Massimiliano Germani, Anna De Ponti, Anna Degrassi, Marina Ciomei, Dario Ballinari, Elena Casale, Maria G. Brasca, Laura Gianellini, Gianpaolo Fogliatto
Supplementary Methods - PDF file 56K, Time-lapse imaging of A375 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890811bb8dc8943c26d3ed639f1dc414
https://doi.org/10.1158/1078-0432.22451820
https://doi.org/10.1158/1078-0432.22451820
Autor:
Claudio Dalvit, Carlo Visco, Federico Riccardi Sirtori, Gianpaolo Fogliatto, Maristella Colombo, Dannica Caronni, Mauro Paolucci, Luca Regazzoni
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 76
ESI-MS is a well established technique for the study of biopolymers (nucleic acids, proteins) and their non covalent adducts, due to its capacity to detect ligand-target complexes in the gas phase and allows inference of ligand-target binding in solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0a89cf077d0a41dd556e31b4cdcc2a
https://pubmed.ncbi.nlm.nih.gov/25952103
https://pubmed.ncbi.nlm.nih.gov/25952103
Autor:
Nilla Avanzi, Federico Riccardi-Sirtori, Serena Bettoni, Sandrine Thieffine, Rita Perego, Francesca Quartieri, Mauro Paolucci, Gianluca Papeo, Antonella Leone, Rosita Lupi, Alessia Montagnoli
Publikováno v:
Journal of biomolecular screening. 19(8)
PARP inhibitors are an exciting new class of antineoplastic drugs that have been proven to be efficacious as single agents in cancer settings with inherent DNA repair defects, as well as in combination with DNA-damaging chemotherapeutics. Currently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a5b4ae3e2aff60c67287305b41fd86
https://pubmed.ncbi.nlm.nih.gov/24916412
https://pubmed.ncbi.nlm.nih.gov/24916412
Autor:
Fabio Zuccotto, Maria Gabriella Brasca, Francesco Sola, Carlo Visco, Anna Degrassi, Arturo Galvani, Marco Guanci, Barbara Valsasina, Enrico Pesenti, Elena Casale, Laura Gianellini, Marina Ciomei, Mauro Paolucci, Paolo Polucci, Massimiliano Germani, Sergio Mantegani, Gianpaolo Fogliatto, M. Russo, Eduard R. Felder, Anna De Ponti, Dario Ballinari, Antonella Isacchi, Daniele Donati
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 19(13)
Purpose: Recent developments of second generation Hsp90 inhibitors suggested a potential for development of this class of molecules also in tumors that have become resistant to molecular targeted agents. Disease progression is often due to brain meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cdb82038714857ece02a6efdb3960c
https://pubmed.ncbi.nlm.nih.gov/23674492
https://pubmed.ncbi.nlm.nih.gov/23674492
Autor:
Nadia Amboldi, Daniele Donati, Sergio Mantegani, Enrico Pesenti, Gianpaolo Fogliatto, Laura Gianellini, Antonella Isacchi, A. De Ponti, Marco Guanci, Mauro Paolucci
Publikováno v:
European Journal of Cancer Supplements. 8:52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66621896846aeef10ba4d104be7f483a
https://doi.org/10.1016/s1359-6349(10)71852-8
https://doi.org/10.1016/s1359-6349(10)71852-8
Autor:
Antonella Ciavolella, Francesco Sola, Alessandra Scolaro, Sandrine Thieffine, Barbara Forte, Gianluca Papeo, Laura Gianellini, Helena Posteri, Antonella Leone, Francesco Caprera, Marco Guanci, Mauro Paolucci, Fabio Zuccotto, Federico Riccardi-Sirtori, Sonia Rainoldi, Elena Casale, Rosita Lupi, Jürgen Moll, Rita Perego, Alessia Montagnoli, Paolo Orsini, Daniele Donati, Clara Albanese
Publikováno v:
Cancer Research. 70:691-691
Poly (ADP-ribose) polymerase 1 and 2 (Parp-1 and Parp-2) are nuclear enzymes responsible for signaling the presence of DNA damages by catalyzing the addition of ADP-ribose units to DNA, histones and various DNA repair enzymes, thus facilitating DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c112b0841dd7e869d13c4e868232232c
https://doi.org/10.1158/1538-7445.am10-691
https://doi.org/10.1158/1538-7445.am10-691
Autor:
Elena Casale, Mauro Paolucci, Francesco Sola, Fabio Zuccotto, Dario Ballinari, Maria Gabriella Brasca, Nadia Amboldi, Sergio Mantegani, Gianpaolo Fogliatto, Antonella Isacchi, Daniele Donati, Carlo Visco, Francesco Colotta, Juergen Moll, Francesco Caprera, Paolo Cappella, Arturo Galvani, Enrico Pesenti, Eduard R. Felder, Marco Guanci, Anna De Ponti, Barbara Valsasina
Publikováno v:
Molecular Cancer Therapeutics. 8:A213-A213
The molecular chaperone heat shock protein 90 (HSP90) is essential for the conformational maturation and stability of a variety of proteins, including kinases, transcription factors, telomerase, and other key proteins implicated in cancer development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0630b261f1ee7c5e8c82eebab34848b7
https://doi.org/10.1158/1535-7163.targ-09-a213
https://doi.org/10.1158/1535-7163.targ-09-a213