Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Mauro Montalbano"'
Autor:
Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has bee
Externí odkaz:
https://doaj.org/article/e82630aa9dc645a094f19b3dcebd97b6
Autor:
Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy
Externí odkaz:
https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
Autor:
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt, Rakez Kayed
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract The transcription factor, p53, is critical for many important cellular functions involved in genome integrity, including cell cycle control, DNA damage response, and apoptosis. Disruption of p53 results in a wide range of disorders including
Externí odkaz:
https://doaj.org/article/89d5269d42b94a85852128d51a041c5f
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder associated with structural and functional alterations of brain cells causing progressive deterioration of memory and other cognitive functions. Recent studies demonstra
Externí odkaz:
https://doaj.org/article/92321c3161264a488a09bcbbbd00f8ad
Autor:
Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105130- (2020)
Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in
Externí odkaz:
https://doaj.org/article/d9510ba996114ef685a27d88a84a1bf5
Autor:
Bartosz Szczesny, Michela Marcatti, Akbar Ahmad, Mauro Montalbano, Attila Brunyánszki, Sofia-Iris Bibli, Andreas Papapetropoulos, Csaba Szabo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract This report identifies mitochondrial DNA (mtDNA) as a target and active mediator that links low-level oxidative stress to inflammatory response in pulmonary epithelial cells. Extrusion of mtDNA into the bronchoalveolar lavage fluid occurs as
Externí odkaz:
https://doaj.org/article/7eeba3dbce074d0b8540463c8f17b8c1
Autor:
Luca Cicalese, Giuseppe Curcuru, Mauro Montalbano, Ali Shirafkan, Jeremias Georgiadis, Cristiana Rastellini
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185610 (2017)
The incidence of hepatocellular carcinoma (HCC), the most common primary liver cancer, is increasing in the US and tripled during the past two decades. The reasons for such phenomenon remain poorly understood. Texas is among continental states with t
Externí odkaz:
https://doaj.org/article/c4395a845ab14440b76e0eca50ce6980
Autor:
Mauro Montalbano, Giuseppe Curcurù, Ali Shirafkan, Renza Vento, Cristiana Rastellini, Luca Cicalese
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153613 (2016)
Isolation of hepatocytes from cirrhotic human livers and subsequent primary culture are important new tools for laboratory research and cell-based therapeutics in the study of hepatocellular carcinoma (HCC). Using such techniques, we have previously
Externí odkaz:
https://doaj.org/article/3093883fa8e04becb31e062cae4c4fca
Autor:
Mauro, Montalbano1 (AUTHOR) mamontal@utmb.edu, Ugo, Perricone2 (AUTHOR) uperricone@fondazionerimed.com, Walton, Zachary3 (AUTHOR) zcwalton@utmb.edu, Ali, Shirafkan4 (AUTHOR) Ali.Shirafkan@rwjbh.org, Rastellini, Cristiana5 (AUTHOR) crrastel@utmb.edu, Cicalese, Luca6 (AUTHOR) lucicale@utmb.edu
Publikováno v:
International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p10922. 15p.
Autor:
Marco Luciani, Mauro Montalbano, Luca Troncone, Camilla Bacchin, Keita Uchida, Gianlorenzo Daniele, Bethany Jacobs Wolf, Helen M Butler, Justin Kiel, Stefano Berto, Cortney Gensemer, Kelsey Moore, Jordan Morningstar, Thamonwan Diteepeng, Onder Albayram, José F Abisambra, Russell A Norris, Thomas G Di Salvo, Benjamin Prosser, Rakez Kayed, Federica del Monte
Publikováno v:
European Heart Journal. 44:1560-1570
Background Amyloid plaques and neurofibrillary tangles, the molecular lesions that characterize Alzheimer’s disease (AD) and other forms of dementia, are emerging as determinants of proteinopathies ‘beyond the brain’. This study aims to establi