Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mauro G. M. Zurini"'
Autor:
Kurt Wüthrich, Malcolm D. Walkinshaw, Jörg Kallen, Gerhard Wider, Mauro G. M. Zurini, Hans Widmer, Claus Spitzfaden
Publikováno v:
Nature. 353:276-279
THE protein cyclophilin is the major intracellular receptor for the immunosuppressive drug cyclosporin A (ref. 1). Cyclosporin A acts as an inhibitor of T-cell activation and can prevent graft rejection in organ and bone marrow transplantation2. Cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1522689c475e1578239504b1a7fda4c5
https://doi.org/10.1038/353276a0
https://doi.org/10.1038/353276a0
Autor:
Johan N. Jansonius, Gaston Pfluegl, Joerg Kallen, Malcolm D. Walkinshaw, Vincent Mikol, Mauro G. M. Zurini
Publikováno v:
FEBS Letters. 276:63-66
Recombinant human cyclophilin has been co-crystallised with a number of peptides to give crystals suitable for X-ray analysis. The crystal complexes for which heavy-atom derivatives have been prepared and X-ray data collected are: cyclophilin with N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9524cbc23ae159e6d6a04d0e7dd81cc9
https://doi.org/10.1016/0014-5793(90)80507-f
https://doi.org/10.1016/0014-5793(90)80507-f
Autor:
Malcolm D. Walkinshaw, Johan N. Jansonius, Mauro G. M. Zurini, Jörg Kallen, Tilman Schirmer, Gaston Pflügl
Publikováno v:
Nature. 361(6407)
Human cyclophilin A (CypA), a ubiquitous intracellular protein of 165 amino acids, is the major receptor for the cyclic undecapeptide immunosuppressant drug cyclosporin A (CsA), which prevents allograft rejection after transplant surgery and is effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b323e85da6dc03aa5a1d665fa5d67a
https://pubmed.ncbi.nlm.nih.gov/8421501
https://pubmed.ncbi.nlm.nih.gov/8421501
Autor:
JÖRG KALLEN, CLAUS SPITZFADEN, MAURO G. M. ZURINI, GERHARD WIDER, HANS WIDMER, KURT WÜTHRICH, MALCOLM D. WALKINSHAW
Publikováno v:
Nature. 356:24-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf11bb2e8b7648cc59cfdd504828088
https://doi.org/10.1038/356024a0
https://doi.org/10.1038/356024a0