Disease Stage and Motor Fluctuation Duration Predict Drug Tolerability: A Real-Life, Prospective Italian Multicenter Study on the Use of Opicapone in Parkinson’s Disease

Autor: Ruggero Bacchin, Marco Liccari, Mauro Catalan, Lucia Antonutti, Paolo Manganotti, Maria Chiara Malaguti, Bruno Giometto

Publikováno v: Drugs - Real World Outcomes, Vol 11, Iss 3, Pp 361-368 (2024)

Abstract Background Opicapone is a third-generation catechol-O-methyl-transferase inhibitor currently used for the treatment of motor fluctuations in Parkinson’s disease. Its benefit and safety have been established by clinical trials; however, dat

Externí odkaz: https://doaj.org/article/610e1e94738f4123be7cd4f520815cf1

Cu-Doped Extremely Small Iron Oxide Nanoparticles with Large Longitudinal Relaxivity: One-Pot Synthesis and in Vivo Targeted Molecular Imaging

Autor: María del Puerto Morales, Fernando Herranz, Lucía Gutiérrez, Jesús Ruiz-Cabello, Irene Fernández-Barahona, Juan Pellico, Sabino Veintemillas-Verdaguer, Miguel A. del Pozo, Mauro Catala

Publikováno v: ACS Omega, Vol 4, Iss 2, Pp 2719-2727 (2019)
ACS Omega
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC

Synthesizing iron oxide nanoparticles for positive contrast in magnetic resonance imaging is the most promising approach to bring this nanomaterial back to the clinical field. The success of this approach depends on several aspects: the longitudinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db24cd60c4178eef39b44cdf351eefd9
https://doaj.org/article/0d81bd7f119c4f5987e49602bf9b5f7b

Neuromuscular assessment of force development, postural, and gait performance under cognitive-motor dual-tasking in healthy older adults and people with early Parkinson's disease: Study protocol for a cross-sectional Mobile Brain/Body Imaging (MoBI) study [version 3; peer review: 2 approved]

Autor: Uros Marusic, Maja Maša Šömen, Manca Peskar, Ales Holobar, Miloš Kalc, Bettina Wollesen, Klaus Gramann, Christoph Michel, Anna Wunderlich, Mauro Catalan, Aleksandar Miladinović, Milos Ajcevic, Alex Buoite Stella, Paolo Manganotti

Publikováno v: Open Research Europe, Vol 3 (2023)

Background Neuromuscular dysfunction is common in older adults and more pronounced in neurodegenerative diseases. In Parkinson's disease (PD), a complex set of factors often prevents the effective performance of activities of daily living that requir

Externí odkaz: https://doaj.org/article/05757dbc32e64d7786389a8a99f57eda

Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

Autor: Matilde Bongianni, Mauro Catalan, Daniela Perra, Elena Fontana, Francesco Janes, Claudio Bertolotti, Luca Sacchetto, Stefano Capaldi, Matteo Tagliapietra, Paola Polverino, Valentina Tommasini, Giulia Bellavita, Elham Ataie Kachoie, Roberto Baruca, Andrea Bernardini, Mariarosaria Valente, Michele Fiorini, Erika Bronzato, Stefano Tamburin, Laura Bertolasi, Lorenzo Brozzetti, Maria Paola Cecchini, Gianluigi Gigli, Salvatore Monaco, Paolo Manganotti, Gianluigi Zanusso

Publikováno v: Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-11 (2022)

Abstract Background In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucleinopathies. It is unknow

Externí odkaz: https://doaj.org/article/e4db3ec8ee7a4112bd5090655fa77fc5

Does the Degree of Trunk Bending Predict Patient Disability, Motor Impairment, Falls, and Back Pain in Parkinson's Disease?

Autor: Christian Geroin, Carlo Alberto Artusi, Marialuisa Gandolfi, Elisabetta Zanolin, Roberto Ceravolo, Marianna Capecci, Elisa Andrenelli, Maria Gabriella Ceravolo, Laura Bonanni, Marco Onofrj, Roberta Telese, Giulia Bellavita, Mauro Catalan, Paolo Manganotti, Sonia Mazzucchi, Sara Giannoni, Laura Vacca, Fabrizio Stocchi, Miriam Casali, Cristian Falup-Pecurariu, Maurizio Zibetti, Alfonso Fasano, Leonardo Lopiano, Michele Tinazzi

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Background: Postural abnormalities in Parkinson's disease (PD) form a spectrum of functional trunk misalignment, ranging from a “typical” parkinsonian stooped posture to progressively greater degrees of spine deviation.Objective: To analyze the a

Externí odkaz: https://doaj.org/article/e7ed2c14d54841e2a778dd7f01cebc8e