Výsledky vyhledávání - "Mauro C. Dal Canto"

CCR2 Regulates Development of Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease

Autor: Stephen D. Miller, Jami L. Bennett, Israel F. Charo, William J. Karpus, Mauro C. Dal Canto, Adam Elhofy

Publikováno v: Viral Immunology. 20:19-33

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease, a murine model for multiple sclerosis, involves recruitment of T cells and macrophages to the CNS after infection. We hypothesized that CCR2, the only known receptor for C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84fd85d6f8cce2f4e73532f61f06d95
https://doi.org/10.1089/vim.2006.0068

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Castration of male C57L/J mice increases susceptibility and estrogen treatment restores resistance to Theiler's virus-induced demyelinating disease

Autor: Chang-Sung Koh, Byung S. Kim, Eui Young So, Hiroyuki Yahikozawa, C. Jane Welsh, Mauro C. Dal Canto, Alyson C. Fuller

Publikováno v: Journal of Neuroscience Research. 85:871-881

Intracerebral inoculation of Theiler's murine encephalomyelitis virus (TMEV) results in immune-mediated demyelination in selective mouse strains. We have previously demonstrated that the males of C57L mice are significantly more susceptible to TMEV-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ecec576b861239becf61b496702e10
https://doi.org/10.1002/jnr.21184

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Anti-CCL2 treatment inhibits Theiler’s murine encephalomyelitis virus-induced demyelinating disease

Autor: Nicholas W. Lukacs, Steven L. Kunkel, Brian T. Fife, Kevin J. Kennedy, William J. Karpus, Mauro C. Dal Canto, Jamie L. Bennett

Publikováno v: Journal of NeuroVirology. 12:251-261

Theiler's murine encephalomyelitis virus induces a demyelinating disease (TMEV-IDD) of the central nervous system (CNS) in susceptible mouse strains with accompanying histopathology characterized by mononuclear cell infiltrates. In susceptible strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6286b0248f5977f45f138baf71fa85c5
https://doi.org/10.1080/13550280600873819

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Gender Bias in Theiler’s Virus-Induced Demyelinating Disease Correlates with the Level of Antiviral Immune Responses

Autor: Hee Kap Kang, Hiroyuki Yahikozowa, Bongsu Kang, Mauro C. Dal Canto, Alyson C. Fuller, Byung S. Kim

Publikováno v: The Journal of Immunology. 175:3955-3963

Multiple sclerosis is an immune-mediated disease of the CNS and shows a sex-biased distribution in which 60–75% of all cases are female. A mouse model of multiple sclerosis, Theiler’s murine encephalomyelitis virus (TMEV)-induced demyelinating di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd722ae15ccbe5fa8b4229bc06a94ce3
https://doi.org/10.4049/jimmunol.175.6.3955

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Antibody response is required for protection from Theiler's virus-induced encephalitis in C57BL/6 mice in the absence of CD8+ T cells

Autor: Bong Su Kang, Michael A. Lyman, Joann P. Palma, Byung S. Kim, Mauro C. Dal Canto

Publikováno v: Virology. 340:84-94

Intracerebral infection of susceptible mice with Theiler's murine encephalomyelitis virus (TMEV) induces immune-mediated demyelinating disease and this system serves as a relevant infectious model for human multiple sclerosis. It was previously shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958f90a3714a8080740d9998f23a7cf2
https://doi.org/10.1016/j.virol.2005.06.028

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Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models

Autor: Krystyna M. Wozniak, Ajit G. Thomas, Richard J. Miller, Barbara S. Slusher, Anna Liza Monti, Amos Bodner, Raymond P. Roos, Pavel Majer, Camilo Rojas, Mauro C. Dal Canto, Takashi Tsukamoto, Ghanashyam D. Ghadge

Publikováno v: Proceedings of the National Academy of Sciences. 100:9554-9559

Approximately 10% of cases of amyotrophic lateral sclerosis (ALS), a progressive and fatal degeneration that targets motor neurons (MNs), are inherited, and ≈20% of these cases of familial ALS (FALS) are caused by mutations of copper/zinc superoxid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d148410e3fabf2d97b2c9e9e4e45c57f
https://doi.org/10.1073/pnas.1530168100

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CD154 Blockade Results in Transient Reduction in Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease

Autor: Lia M. Haynes, Stephen D. Miller, Laurence M. Howard, Katherine L. Neville, Mauro C. Dal Canto

Publikováno v: Journal of Virology. 77:2247-2250

Transient CD154 blockade at the onset of Theiler's murine encephalomyelitis virus-induced demyelinating disease ameliorated disease progression for 80 days, reduced immune cell infiltration, and transiently increased viral loads in the central nervou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898d28e3e40feb8fc14a9a532e5182d8
https://doi.org/10.1128/jvi.77.3.2247-2250.2003

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Molecular biological approaches to neurological disorders including knockout and transgenic mouse models

Autor: Noriyuki Shibata, Makio Kobayashi, Tatsuo Sawada, Hideaki Oda, Mauro C. Dal Canto, Yoichiro Kato, Koji Uchida, Asao Hirano, Motoko Kawaguchi

Publikováno v: Neuropathology. 22:337-349

Advances of molecular biology have provided a great variety of new approaches to research on human disorders. This article gives an outline of molecular biological approaches to analysis of neurological disorders such as giant cell glioblastoma (GGBM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07c1ed20f77eed51f7ffe1cd23ff235f
https://doi.org/10.1046/j.1440-1789.2002.00449.x

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