Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mauro Bertolino"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 6, Pp 622-632 (2021)
Abstract Merck KGaA observed slight differences in the dissolution of Concor® (bisoprolol) batches over the years. The purpose of this work was to assess the impact of in vitro dissolution on the simulated pharmacokinetics of bisoprolol using in vit
Externí odkaz:
https://doaj.org/article/5c4526a3e83545c88387d95bf5d2e5c2
Autor:
Ana‐Marija Grisic, Akash Khandelwal, Mauro Bertolino, Wilhelm Huisinga, Pascal Girard, Charlotte Kloft
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 11, Pp 628-638 (2020)
This study aimed to explore the currently competing and new semimechanistic clearance models for monoclonal antibodies and the impact of clearance model misspecification on exposure metrics under different study designs exemplified for cetuximab. Six
Externí odkaz:
https://doaj.org/article/6ee1ec8376d042dbb67c4eed3f654082
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 6, Pp 622-632 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 6, Pp 622-632 (2021)
Merck KGaA observed slight differences in the dissolution of Concor® (bisoprolol) batches over the years. The purpose of this work was to assess the impact of in vitro dissolution on the simulated pharmacokinetics of bisoprolol using in vitro–in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd16c8bddf050b3e0593f72c666f4b10
http://europepmc.org/articles/PMC8213417
http://europepmc.org/articles/PMC8213417
Autor:
Pascal Girard, Akash Khandelwal, Charlotte Kloft, Wilhelm Huisinga, Ana-Marija Grisic, Mauro Bertolino
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 11, Pp 628-638 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 11, Pp 628-638 (2020)
This study aimed to explore the currently competing and new semimechanistic clearance models for monoclonal antibodies and the impact of clearance model misspecification on exposure metrics under different study designs exemplified for cetuximab. Six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169eb5e5de8613d69878a5fbac6d6305
Autor:
Derek Janszen, Enrico Vigna, Sergio Peano, Manuela Onidi, Mauro Bertolino, Rafael A. Ponce, Chiara Daghero, Laura Fava, Ping Yu, Jennifer Visich, Michela Carbonatto, Stephanie Steidler, Bruno Roattino, Stacey R. Dillon, Michele Ardizzone
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 105(1)
Atacicept, a soluble recombinant fusion protein of the human immunoglobulin (Ig) G1 Fc and the extracellular domain of the human transmembrane activator and calcium modulator and cyclophylin ligand interactor receptor, acts as an antagonist of both B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebffb6d514762f452a2d2bb2cc999cb
https://pubmed.ncbi.nlm.nih.gov/18522929
https://pubmed.ncbi.nlm.nih.gov/18522929
Publikováno v:
European journal of drug metabolism and pharmacokinetics, 31(2), 109-116. Springer Paris
IL-18 binding protein (BP) neutralizes the activity of IL-18, a cytokine implicated in psoriasis and rheumatoid arthritis (RA). We investigated the pharmacokinetics, pharmacodynamics and safety of recombinant human IL-18 BP (r-hIL-18 BP) in healthy v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b98108fc2eb557094d5533c2614465
https://pure.amc.nl/en/publications/pharmacokinetics-of-il18-binding-protein-in-healthy-volunteers-and-subjects-with-rheumatoid-arthritis-or-plaque-psoriasis(1cdaf6c8-1386-497d-9b89-be2954e217ab).html
https://pure.amc.nl/en/publications/pharmacokinetics-of-il18-binding-protein-in-healthy-volunteers-and-subjects-with-rheumatoid-arthritis-or-plaque-psoriasis(1cdaf6c8-1386-497d-9b89-be2954e217ab).html
Autor:
Michela Carbonatto, Ping Yu, Mauro Bertolino, Enrico Vigna, Stephanie Steidler, Laura Fava, Chiara Daghero, Bruno Roattino, Manuela Onidi, Michele Ardizzone, Sergio Peano, Jennifer Visich, Derek Janszen, Stacey Dillon, Rafael Ponce
Publikováno v:
Toxicological Sciences; Sep2008, Vol. 105 Issue 1, p200-200, 1p