Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Mauro A. A. Castro"'
Autor:
Fernanda G.Q. Barros-Aragão, Talita P. Pinto, Victor C. Carregari, Nathane B.S. Rezende, Thaís L. Pinheiro, Guilherme Reis-de-Oliveira, Mauro J. Cabral-Castro, Daniel C. Queiroz, Paula L.C. Fonseca, Alessandro L. Gonçalves, Gabriel R. de Freitas, Felipe K. Sudo, Paulo Mattos, Fernando A. Bozza, Erika C. Rodrigues, Renato S. Aguiar, Rosana S. Rodrigues, Carlos O. Brandão, Andrea S. Souza, Daniel Martins-de-Souza, Fernanda G. De Felice, Fernanda Tovar-Moll
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 39, Iss , Pp 100805- (2024)
COVID-19 induces acute and persistent neurological symptoms in mild and severe cases. Proposed concomitant mechanisms include direct viral infection and strain, coagulopathy, hypoxia, and neuroinflammation. However, underlying molecular alterations a
Externí odkaz:
https://doaj.org/article/cb3be360f4de4471ba9bd574929065b3
Autor:
Samya Jezine Da Silva, Mauro Jorge Cabral-Castro, Cássia Cristina Alves Gonçalves, Diana Mariani, Orlando Ferreira, Amílcar Tanuri, Marzia Puccioni-Sohler
Publikováno v:
Viruses, Vol 16, Iss 8, p 1247 (2024)
Neurological involvement has been widely reported in SARS-CoV-2 infection. However, viral identification in the cerebrospinal fluid (CSF) is rarely found. The aim of this study is to evaluate the accuracy of virological and immunological biomarkers i
Externí odkaz:
https://doaj.org/article/9fbebbe942fb44a08598c6848060e237
Autor:
A. Gordon Robertson, Khyati Meghani, Lauren Folgosa Cooley, Kimberly A. McLaughlin, Leigh Ann Fall, Yanni Yu, Mauro A. A. Castro, Clarice S. Groeneveld, Aurélien de Reyniès, Vadim I. Nazarov, Vasily O. Tsvetkov, Bonnie Choy, Daniele Raggi, Laura Marandino, Francesco Montorsi, Thomas Powles, Andrea Necchi, Joshua J. Meeks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Checkpoint immunotherapy (CPI) has increased survival for some patients with advanced-stage bladder cancer (BCa). However, most patients do not respond. Here, we characterized the tumor and immune microenvironment in pre- and post-treatment
Externí odkaz:
https://doaj.org/article/2ff28f983edd46ab8e45cdcce91c4760
Autor:
Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Zhiyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, Hikmat A. Al-Ahmadie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Bladder cancer can often exhibit genomic and morphological heterogeneity. Here, the authors use genomics analysis to show lineage plasticity of bladder cancers with squamous differentiation, and identify key transcription factors related to this morp
Externí odkaz:
https://doaj.org/article/626d86eebf314e6e8d115afe8bbcc1dd
Autor:
Joshua I. Warrick, Margaret A. Knowles, Carolyn D. Hurst, Lauren Shuman, Jay D. Raman, Vonn Walter, Jeffrey Putt, Lars Dyrskjøt, Clarice Groeneveld, Mauro A. A. Castro, A. Gordon Robertson, David J. DeGraff
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Human cancers display a restricted set of expression profiles, despite diverse mutational drivers. This has led to the hypothesis that select sets of transcription factors act on similar target genes as an integrated network, buffering a tum
Externí odkaz:
https://doaj.org/article/5d6653d9f5dd4dd3b7afe6712bdf88da
Publikováno v:
Jornal de Assistência Farmacêutica e Farmacoeconomia, Vol 2, Iss 4 (2022)
Estima-se que a não-adesão atinja quase a metade dos usuários crônicos de medicamento. Objetivo: considerando a importância da identificação da não-adesão à farmacoterapia, tem-se o objetivo de mapear a literatura existente no que diz respe
Externí odkaz:
https://doaj.org/article/eab0409525b64d3d9f120227661a298a
Autor:
Samya Jezine DA SILVA, Mauro Jorge CABRAL-CASTRO, Maria Angélica GUIMARÃES, José Mauro PERALTA, Marzia PUCCIONI-SOHLER
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 78, Iss 3, Pp 163-168 (2020)
Abstract Herpes simplex virus (HSV) is a cause of a severe disease of the central nervous system (CNS) in humans. The demonstration of specific antibodies in the cerebrospinal fluid (CSF) may contribute to the retrospective neurological diagnosis. Ho
Externí odkaz:
https://doaj.org/article/f2e415e5cff74e22b0bb9fbbc5ee6cad
Autor:
Joshua I. Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M. Craig, Lan L. Gellert, Mauro A. A. Castro, A. Gordon Robertson, Fengshen Kuo, Irina Ostrovnaya, Judy Sarungbam, Ying-bei Chen, Anuradha Gopalan, Sahussapont J. Sirintrapun, Samson W. Fine, Satish K. Tickoo, Kwanghee Kim, Jasmine Thomas, Nagar Karan, Sizhi Paul Gao, Timothy N. Clinton, Andrew T. Lenis, Timothy A. Chan, Ziyu Chen, Manisha Rao, Travis J. Hollman, Yanyun Li, Nicholas D. Socci, Shweta Chavan, Agnes Viale, Neeman Mohibullah, Bernard H. Bochner, Eugene J. Pietzak, Min Yuen Teo, Gopa Iyer, Jonathan E. Rosenberg, Dean F. Bajorin, Matthew Kaag, Suzanne B. Merrill, Monika Joshi, Rosalyn Adam, John A. Taylor, Peter E. Clark, Jay D. Raman, Victor E. Reuter, Yu Chen, Samuel A. Funt, David B. Solit, David J. DeGraff, Hikmat A. Al-Ahmadie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/2eef054bb2c44933b8d666fcf7c5d045
Autor:
Thalia Medeiros, Lilian Santos Alves, Mauro Jorge Cabral-Castro, Alice Ramos Oliveira Silva, Analúcia Rampazzo Xavier, Dylan Burger, Jorge Reis Almeida, Andrea Alice Silva
Publikováno v:
Diagnostics, Vol 12, Iss 11, p 2600 (2022)
Kidney injury is an important outcome associated with COVID-19 severity. In this regard, alterations in urinary extracellular vesicles (uEVs) could be detected in the early phases of renal injury and may be reflective of the inflammatory process. Thi
Externí odkaz:
https://doaj.org/article/5f785ee62ac14d00baf36a43f8dbbb9f
Autor:
Renata Moll-Bernardes, Andrea Silvestre de Sousa, Ariane V. S. Macedo, Renato D. Lopes, Narendra Vera, Luciana C. R. Maia, André Feldman, Guilherme D. A. S. Arruda, Mauro J. C. Castro, Pedro M. Pimentel-Coelho, Denílson C. de Albuquerque, Thiago Ceccatto de Paula, Thyago A. B. Furquim, Vitor A. Loures, Karla G. D. Giusti, Nathália M. de Oliveira, Fábio A. De Luca, Marisol D. M. Kotsugai, Rafael A. M. Domiciano, Mayara Fraga Santos, Olga Ferreira de Souza, Fernando A. Bozza, Ronir Raggio Luiz, Emiliano Medei
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Cardiovascular comorbidities such as hypertension and inflammatory response dysregulation are associated with worse COVID-19 prognoses. Different cytokines have been proposed to play vital pathophysiological roles in COVID-19 progression,
Externí odkaz:
https://doaj.org/article/c1c347615fad43afb5d566085f7c2d63