Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Mauro, Montalbano"'
Autor:
Mauro, Montalbano1 (AUTHOR) mamontal@utmb.edu, Ugo, Perricone2 (AUTHOR) uperricone@fondazionerimed.com, Walton, Zachary3 (AUTHOR) zcwalton@utmb.edu, Ali, Shirafkan4 (AUTHOR) Ali.Shirafkan@rwjbh.org, Rastellini, Cristiana5 (AUTHOR) crrastel@utmb.edu, Cicalese, Luca6 (AUTHOR) lucicale@utmb.edu
Publikováno v:
International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p10922. 15p.
Autor:
Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy
Externí odkaz:
https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
Autor:
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt, Rakez Kayed
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract The transcription factor, p53, is critical for many important cellular functions involved in genome integrity, including cell cycle control, DNA damage response, and apoptosis. Disruption of p53 results in a wide range of disorders including
Externí odkaz:
https://doaj.org/article/89d5269d42b94a85852128d51a041c5f
Autor:
Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has bee
Externí odkaz:
https://doaj.org/article/e82630aa9dc645a094f19b3dcebd97b6
Autor:
Marco Luciani, Mauro Montalbano, Luca Troncone, Camilla Bacchin, Keita Uchida, Gianlorenzo Daniele, Bethany Jacobs Wolf, Helen M Butler, Justin Kiel, Stefano Berto, Cortney Gensemer, Kelsey Moore, Jordan Morningstar, Thamonwan Diteepeng, Onder Albayram, José F Abisambra, Russell A Norris, Thomas G Di Salvo, Benjamin Prosser, Rakez Kayed, Federica del Monte
Publikováno v:
European Heart Journal. 44:1560-1570
Background Amyloid plaques and neurofibrillary tangles, the molecular lesions that characterize Alzheimer’s disease (AD) and other forms of dementia, are emerging as determinants of proteinopathies ‘beyond the brain’. This study aims to establi
Autor:
Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105130- (2020)
Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in
Externí odkaz:
https://doaj.org/article/d9510ba996114ef685a27d88a84a1bf5
Autor:
Alice Bittar, Rabab Al-Lahham, Nemil Bhatt, Kenya Moore, Mauro Montalbano, Cynthia Jerez, Leiana Fung, Salome McAllen, Anna Ellsworth, Rakez Kayed
Publikováno v:
Journal of Alzheimer's Disease. 90:1103-1122
Background: Tau oligomers are one of the most toxic species, displaying prion-like strains which have different conformations resulting in different tauopathies. Passive immunotherapy targeting different tau species is a promising therapeutic approac
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder associated with structural and functional alterations of brain cells causing progressive deterioration of memory and other cognitive functions. Recent studies demonstra
Externí odkaz:
https://doaj.org/article/92321c3161264a488a09bcbbbd00f8ad
Autor:
Bartosz Szczesny, Michela Marcatti, Akbar Ahmad, Mauro Montalbano, Attila Brunyánszki, Sofia-Iris Bibli, Andreas Papapetropoulos, Csaba Szabo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract This report identifies mitochondrial DNA (mtDNA) as a target and active mediator that links low-level oxidative stress to inflammatory response in pulmonary epithelial cells. Extrusion of mtDNA into the bronchoalveolar lavage fluid occurs as
Externí odkaz:
https://doaj.org/article/7eeba3dbce074d0b8540463c8f17b8c1
Autor:
Michela Marcatti, Anna Fracassi, Mauro Montalbano, Nicha Puangmalai, Nemil Bhatt, Chandramouli Natarajan, Jutatip Guptarak, Balaji Krishnan, Rakez Kayed, Giulio Taglialatela
Publikováno v:
Alzheimer's & Dementia. 18