Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Mauro, Fasano"'
Autor:
Paola Granata, Alessandra Zito, Dario Cocciadiferro, Antonio Novelli, Chiara Pessina, Tommaso Mazza, Matteo Ferri, Paolo Piccinelli, Chiara Luoni, Cristiano Termine, Mauro Fasano, Rosario Casalone
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Autistic Spectrum Disorder (ASD) is a neurodevelopmental disorder with a strong genetic component and high heterogeneity. Essential ASD refers to patients who do not have other comorbidities. This study aimed to investigate the ge
Externí odkaz:
https://doaj.org/article/872fb87bc0864d7fb98d4d1990882c75
Autor:
Mariam Shallak, Tiziana Alberio, Mauro Fasano, Maria Monti, Ilaria Iacobucci, Julien Ladet, Franck Mortreux, Roberto S. Accolla, Greta Forlani
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play important roles in HTLV-1 infectivity and in HTLV-1-associated pathologies
Externí odkaz:
https://doaj.org/article/401e1068b2264f0f86bc77d4eebebdb7
Autor:
Paola Granata, Dario Cocciadiferro, Alessandra Zito, Chiara Pessina, Alessandro Bassani, Fabio Zambonin, Antonio Novelli, Mauro Fasano, Rosario Casalone
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The 16p13.11 microdeletion, whose prevalence in the general population is about 0.04%, is known in literature as a predisposition factor to neurodevelopmental disorders, being found in about 0.13% of patients with schizophrenia, in 0.5–0.6% of pati
Externí odkaz:
https://doaj.org/article/1e003e08c96e4b85ae41d59ee7bd334b
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 683 (2023)
Hemoproteins include several heme-binding proteins with distinct structure and function. The presence of the heme group confers specific reactivity and spectroscopic properties to hemoproteins. In this review, we provide an overview of five families
Externí odkaz:
https://doaj.org/article/ccdc43ab384b4b9691ee8ad9a0e57259
Autor:
Alessandra Zito, Marta Lualdi, Paola Granata, Dario Cocciadiferro, Antonio Novelli, Tiziana Alberio, Rosario Casalone, Mauro Fasano
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Gene set enrichment analysis (GSEA) is a powerful tool to associate a disease phenotype to a group of genes/proteins. GSEA attributes a specific weight to each gene/protein in the input list that depends on a metric of choice, which is usually repres
Externí odkaz:
https://doaj.org/article/f5d1ee5b7a4742b78f4c1544eebc8d94
Autor:
Mara Zilocchi, Ilaria Colugnat, Marta Lualdi, Monica Meduri, Federica Marini, Victor Corasolla Carregari, Mohamed Taha Moutaoufik, Sadhna Phanse, Luisa Pieroni, Mohan Babu, Barbara Garavaglia, Mauro Fasano, Tiziana Alberio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mutations in PARK2 gene are the most frequent cause of familial forms of Parkinson’s disease (PD). This gene encodes Parkin, an E3 ubiquitin ligase involved in several cellular mechanisms, including mitophagy. Parkin loss-of-function is responsible
Externí odkaz:
https://doaj.org/article/51ceb95f2cac41d79ea02df87249d100
Autor:
Tiziana Alberio, Greta Forlani, Marta Lualdi, Giovanna Tosi, Roberto S. Accolla, Mauro Fasano
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Fibrinogen is a central player in the blood coagulation cascade and one of the most abundant plasma proteins. This glycoprotein also triggers important events (e.g., cell spreading, the respiratory burst and degranulation) in neut
Externí odkaz:
https://doaj.org/article/73021201f9704d3cbf83497994eef84d
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 188 (2022)
The sudden outbreak and worldwide spread of the SARS-CoV-2 pandemic pushed the scientific community to find fast solutions to cope with the health emergency. COVID-19 complexity, in terms of clinical outcomes, severity, and response to therapy sugges
Externí odkaz:
https://doaj.org/article/33d9ae250b6041aaba9247bd49da955d
Autor:
Marta Lualdi, Maurizio Ronci, Mara Zilocchi, Federica Corno, Emily S. Turilli, Mauro Sponchiado, Antonio Aceto, Tiziana Alberio, Mauro Fasano
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Parkinson’s disease (PD) is the second most frequent neurodegenerative disease worldwide and the availability of early biomarkers and novel biotargets represents an urgent medical need. The main pathogenetic hallmark of PD is the specific loss of n
Externí odkaz:
https://doaj.org/article/6a450c8179904753b92af01846627428
Publikováno v:
EuPA Open Proteomics, Vol 10, Iss C, Pp 24-27 (2016)
The mitochondrial human proteome project (mt-HPP) was initiated by the Italian HPP group as a part of both the chromosome-centric initiative (C-HPP) and the “biology and disease driven” initiative (B/D-HPP). In recent years several reports highli
Externí odkaz:
https://doaj.org/article/4dccbf8ebf634cdc9ed490cafa18be47