Zobrazeno 1 - 10
of 457
pro vyhledávání: '"Mauro, Alini"'
Autor:
Sima Bordbar, Zhen Li, Nasrin Lotfibakhshaiesh, Jafar Ai, Amin Tavassoli, Nima Beheshtizadeh, Letizia Vainieri, Mehdi Khanmohammadi, Forough Azam Sayahpour, Mohamadreza Baghaban Eslaminejad, Mahmoud Azami, Sibylle Grad, Mauro Alini
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Physiochemical tissue inducers and mechanical stimulation are both efficient variables in cartilage tissue fabrication and regeneration. In the presence of biomolecules, decellularized extracellular matrix (ECM) may trigger and enhance stem
Externí odkaz:
https://doaj.org/article/3b82be9496d74eddb475de2d26e7dac5
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Discogenic pain is associated with deep nerve ingrowth in annulus fibrosus tissue (AF) of intervertebral disc (IVD). To model AF nerve ingrowth, primary bovine dorsal root ganglion (DRG) micro‐scale tissue units are spatially organised aro
Externí odkaz:
https://doaj.org/article/63db4b9bb14e43dd8bc623c545f70386
Autor:
Elena Della Bella, Ursula Menzel, Andreas Naros, Eva Johanna Kubosch, Mauro Alini, Martin J Stoddart
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303035 (2024)
Fracture non-unions affect many patients worldwide, however, known risk factors alone do not predict individual risk. The identification of novel biomarkers is crucial for early diagnosis and timely patient treatment. This study focused on the identi
Externí odkaz:
https://doaj.org/article/9fbb50937ae84748910c5b5952e65ca6
Publikováno v:
Journal of Orthopaedic Translation, Vol 38, Iss , Pp 106-116 (2023)
Background: Osteoarthritis (OA) is the most common degenerative joint disease, mainly affecting the elderly worldwide, for which the drug treatment remains a major challenge. Low-grade inflammation plays a pivotal role in OA onset and progression. Ex
Externí odkaz:
https://doaj.org/article/3b8eaf88ff934dbbb4ffa0b7e683e6fe
Autor:
Riccardo Tognato, Romedi Parolini, Shahrbanoo Jahangir, Junxuan Ma, Sammy Florczak, R. Geoff Richards, Riccardo Levato, Mauro Alini, Tiziano Serra
Publikováno v:
Materials Today Bio, Vol 22, Iss , Pp 100775- (2023)
Herein we show an accessible technique based on Faraday waves that assist the rapid assembly of osteoinductive β-Tricalcium phosphate (β-TCP) particles as well as human osteoblast pre-assembled in spheroids. The hydrodynamic forces originating at
Externí odkaz:
https://doaj.org/article/29190518d8314391833d6a8b1fdb96bf
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/3125d99f93bb4bc681f976108328e0b0
Autor:
Jan Gewiess, Janick Eglauf, Astrid Soubrier, Sibylle Grad, Mauro Alini, Marianna Peroglio, Junxuan Ma
Publikováno v:
JOR Spine, Vol 6, Iss 3, Pp n/a-n/a (2023)
Abstract Introduction Mechanical overloading can trigger a degenerative‐like cascade in an organ culture of intervertebral disc (IVD). Whether the overloaded IVD can influence the activation of nociceptors (i.e., the damage sensing neurons) remains
Externí odkaz:
https://doaj.org/article/039fb1b1a27b44e786fb9d34c71386b1
Publikováno v:
JOR Spine, Vol 6, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/3d4147502be94d818b5866c171245978
Autor:
Penghui Zhang, Kaihu Li, Amir Kamali, Reihane Ziadlou, Paras Ahmad, Xinluan Wang, R. Geoff Richards, Mauro Alini, Valentina Basoli, Zhen Li, Sibylle Grad
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-19 (2022)
Abstract Osteoarthritis (OA) is one of the most common musculoskeletal degenerative diseases and contributes to heavy socioeconomic burden. Current pharmacological and conventional non-pharmacological therapies aim at relieving the symptoms like pain
Externí odkaz:
https://doaj.org/article/ea1e9bae08d64691baf7841e5e594eac
Autor:
Peng Guo, Xizhe Liu, Penghui Zhang, Zhongyuan He, Zhen Li, Mauro Alini, R. Geoff Richards, Sibylle Grad, Martin J. Stoddart, Guangqian Zhou, Xuenong Zou, Danny Chan, Wei Tian, Dafu Chen, Manman Gao, Zhiyu Zhou, Shaoyu Liu
Publikováno v:
Bioactive Materials, Vol 9, Iss , Pp 281-298 (2022)
The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined, which significantly limits the application of such bioactive materials. Here, the transcriptional landsca
Externí odkaz:
https://doaj.org/article/96dcc4ab12cf48b58dcb1258954453df