Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Maurizio Viale"'
Publikováno v:
Inorganics, Vol 12, Iss 6, p 167 (2024)
Novel platinum(II) complexes of 4′-substituted terpyridine ligands were synthesized and characterized. Each complex had a different biomolecule (amine, glucose, biotin and hyaluronic acid) as a targeting motif, potentially improving therapeutic out
Externí odkaz:
https://doaj.org/article/0e7f929114c54f9598ca13294f27cc7d
Autor:
Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Essam Nageh Sholkamy, Assem Barakat, Maurizio Viale, Paola Menichini, Andrea Speciale, Fabrizio Loiacono, Mohammad Azam, Ved Prakash Verma, Sammer Yousuf, Mohamed Teleb
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-23 (2023)
Abstract Recently, cancer research protocols have introduced clinical-stage spirooxindole-based MDM2 inhibitors. However, several studies reported tumor resistance to the treatment. This directed efforts to invest in designing various combinatorial l
Externí odkaz:
https://doaj.org/article/3163e75f3ed94e9b89596f628803db7b
Autor:
Noemi Bognanni, Maurizio Viale, Luana La Piana, Simone Strano, Rosaria Gangemi, Cinzia Lombardo, Maria Teresa Cambria, Graziella Vecchio
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 374 (2023)
In the last years, nanoparticles based on cyclodextrins have been widely investigated for the delivery of anticancer drugs. In this work, we synthesized nanoparticles with a hyaluronic acid backbone functionalized with cyclodextrins under green condi
Externí odkaz:
https://doaj.org/article/eda421aae2304ea78ac8e76daf862dfd
Autor:
Maurizio Viale, Giovanni Lentini, Rosaria Gangemi, Patrizio Castagnola, Gualtiero Milani, Silvia Ravera, Nadia Bertola, Antonio Carrieri, Maria Maddalena Cavalluzzi
Publikováno v:
Molecules, Vol 27, Iss 22, p 7870 (2022)
In a previous paper, we demonstrated the synergistic action of the anti-ischemic lubeluzole (Lube S) on the cytotoxic activity of doxorubicin (Dox) and paclitaxel in human ovarian cancer A2780 and lung cancer A549 cells. In the present paper, we exte
Externí odkaz:
https://doaj.org/article/9ebb1bebc87942aeb3ed085d71bbf9ef
Autor:
Noemi Bognanni, Maurizio Viale, Alessia Distefano, Rita Tosto, Nadia Bertola, Fabrizio Loiacono, Marco Ponassi, Domenico Spinelli, Giuseppe Pappalardo, Graziella Vecchio
Publikováno v:
Molecules, Vol 26, Iss 19, p 6046 (2021)
In the few last years, nanosystems have emerged as a potential therapeutic approach to improve the efficacy and selectivity of many drugs. Cyclodextrins (CyDs) and their nanoparticles have been widely investigated as drug delivery systems. The covale
Externí odkaz:
https://doaj.org/article/6c881835cb804792b277f1d55e87fd5a
Publikováno v:
Molecules, Vol 26, Iss 6, p 1724 (2021)
Over the years, cyclodextrin uses have been widely reviewed and their proprieties provide a very attractive approach in different biomedical applications. Cyclodextrins, due to their characteristics, are used to transport drugs and have also been stu
Externí odkaz:
https://doaj.org/article/207306089a024eceb45b360f88307c88
Autor:
Matteo Micucci, Maurizio Viale, Alberto Chiarini, Domenico Spinelli, Maria Frosini, Cinzia Tavani, Massimo Maccagno, Lara Bianchi, Rosaria Gangemi, Roberta Budriesi
Publikováno v:
Molecules, Vol 25, Iss 5, p 1056 (2020)
Our research groups have been involved for many years in studies aimed at identifying new active organic compounds endowed with pharmacological properties. In this work, we focused our attention on the evaluation of cardiovascular and molecular drug
Externí odkaz:
https://doaj.org/article/60cdc34dff5047fca3f2b0b3bea77510
Autor:
Domenico Spinelli, Roberta Budriesi, Barbara Cosimelli, Elda Severi, Matteo Micucci, Massimo Baroni, Fabio Fusi, Pierfranco Ioan, Simon Cross, Maria Frosini, Simona Saponara, Rosanna Matucci, Camillo Rosano, Maurizio Viale, Alberto Chiarini, Emanuele Carosati
Publikováno v:
Molecules, Vol 19, Iss 10, Pp 16543-16572 (2014)
As a result of the ring-into-ring conversion of nitrosoimidazole derivatives, we obtained a molecular scaffold that, when properly decorated, is able to decrease inotropy by blocking L-type calcium channels. Previously, we used this scaffold to devel
Externí odkaz:
https://doaj.org/article/ddf26899b337451bb7cef0ca2fc0bb1d
Autor:
Hakima Chicha, El Mostapha Rakib, Latifa Bouissane, Maurizio Viale, Mohamed Saadi, Lahcen El Ammari
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 7, Pp e2-e2 (2014)
The affiliation address of one of the authors in the paper by Chicha et al. [Acta Cryst. (2014), E70, o624] is corrected.
Externí odkaz:
https://doaj.org/article/8212533a8a6f4427ba8d68c3f142a4e7
Autor:
Roberta Panebianco, Maurizio Viale, Fabrizio Loiacono, Valeria Lanza, Danilo Milardi, Graziella Vecchio
Publikováno v:
ChemMedChem. 18