Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Maurizio Taddei"'
Autor:
Luisa Maresca, Enrica Crivaro, Francesca Migliorini, Giulia Anichini, Alessandro Giammona, Sara Pepe, Federica Poggialini, Chiara Vagaggini, Giuseppe Giannini, Serena Sestini, Lorenzo Borgognoni, Andrea Lapucci, Elena Dreassi, Maurizio Taddei, Fabrizio Manetti, Elena Petricci, Barbara Stecca
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106858- (2023)
Aberrant activation of Hedgehog (HH) signaling in cancer is the result of genetic alterations of upstream pathway components (canonical) or other oncogenic mechanisms (noncanonical), that ultimately concur to activate the zinc-finger transcription fa
Externí odkaz:
https://doaj.org/article/3edd0903f8c04391913aff178e1c0782
Publikováno v:
Molecules, Vol 28, Iss 6, p 2445 (2023)
The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking
Externí odkaz:
https://doaj.org/article/e5a082e914bd49c0b49206893d730890
Autor:
Alessio Dessì, Adalgisa Sinicropi, Sanaz Mohammadpourasl, Riccardo Basosi, Maurizio Taddei, Fabrizia Fabrizi de Biani, Massimo Calamante, Lorenzo Zani, Alessandro Mordini, Pamela Bracq, Daniele Franchi, Gianna Reginato
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 7614-7627 (2019)
Externí odkaz:
https://doaj.org/article/481c1c322cc04c94bde0d668463ecfdc
Autor:
Elena Petricci, Simone Zurzolo, Camilla Matassini, Samuele Maramai, Francesca Cardona, Andrea Goti, Maurizio Taddei
Publikováno v:
Molecules, Vol 27, Iss 15, p 4762 (2022)
A general method for the synthesis of pyrrolizidine derivatives using an intramolecular hydroaminomethylation protocol (HAM) under microwave (MW) dielectric heating is reported. Starting from a 3,4-bis(benzyloxy)-2-[(benzyloxy)methyl]-5-vinylpyrrolid
Externí odkaz:
https://doaj.org/article/438ab9c3b4ca4a66ada6edea3ac0f44a
Autor:
Ferdinando Maria Milazzo, Loredana Vesci, Anna Maria Anastasi, Caterina Chiapparino, Antonio Rosi, Giuseppe Giannini, Maurizio Taddei, Elena Cini, Valentina Faltoni, Elena Petricci, Gianfranco Battistuzzi, Laura Salvini, Valeria Carollo, Rita De Santis
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Targeted therapy using monoclonal antibodies conjugated to toxins is gaining space in the treatment of cancer. Here, we report the anti-tumor effect of a new antibody drug conjugate (ADC) delivering a HDAC inhibitor to ErbB2+ solid tumors. Trastuzuma
Externí odkaz:
https://doaj.org/article/9cacfddaa65c4f5289baf37bf07c9122
Publikováno v:
Molecules, Vol 26, Iss 13, p 3917 (2021)
The synthesis of 2-substituted indoles starting from the corresponding unprotected 2-alkynylanilines was made possible in 3% TPGS-750-M water using Pd(OAc)2 alone as the catalyst. The reaction was sensitive to the heating mode respect to the nature o
Externí odkaz:
https://doaj.org/article/a81f97fea71f4b6ab6ba957010629186
Autor:
Maurizio Taddei
Publikováno v:
The Journal of Transcultural Studies, Vol 6, Iss 1, Pp 34-74 (2015)
The focus of this study by the late Maurizio Taddei, which was translated from the Italian, lies on narratives of the Buddha’s life in friezes on stupas built to contain relics of the Buddha in Gandhāra (in today’s Pakistan) between the late fir
Externí odkaz:
https://doaj.org/article/34db92764d594026bb86633d959f6e1e
Autor:
Julien Ferent, Loïc Cochard, Hélène Faure, Maurizio Taddei, Heidi Hahn, Martial Ruat, Elisabeth Traiffort
Publikováno v:
Stem Cell Reports, Vol 3, Iss 2, Pp 312-323 (2014)
In the adult brain, self-renewal is essential for the persistence of neural stem cells (NSCs) throughout life, but its regulation is still poorly understood. One NSC can give birth to two NSCs or one NSC and one transient progenitor. A correct balanc
Externí odkaz:
https://doaj.org/article/b071b95047814f7187ff97364fd1f161
Autor:
Alessandra Chiarenza, Fabrizio Manetti, Elena Petricci, Martial Ruat, Antonella Naldini, Maurizio Taddei, Fabio Carraro
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149919 (2016)
The most relevant therapeutic approaches to treat CML rely on the administration of tyrosine kinase inhibitors (TKIs) like Imatinib, which are able to counteract the activity of Bcr-Abl protein increasing patient's life expectancy and survival. Unfor
Externí odkaz:
https://doaj.org/article/1dbd6aad2a8848e7aaef171c651d7254
Publikováno v:
Catalysts, Vol 7, Iss 3, p 89 (2017)
Microwave-assisted organic synthesis (MAOS) provides a novel and efficient means of achieving heat organic reactions. Nevertheless, the potential arcing phenomena via microwave (MW) interaction with solid metal catalysts has limited its use by organi
Externí odkaz:
https://doaj.org/article/44faaf325bb242949fc3d3febabcee5f