Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maurizio Orl"'
Autor:
Lia Millucci, Lorenzo Ghezzi, Eugenio Paccagnini, Giovanna Giorgetti, Cecilia Viti, Daniela Braconi, Marcella Laschi, Michela Geminiani, Patrizia Soldani, Pietro Lupetti, Maurizio Orlandini, Chiara Benvenuti, Federico Perfetto, Adriano Spreafico, Giulia Bernardini, Annalisa Santucci
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Background. Alkaptonuria, a rare autosomal recessive metabolic disorder caused by deficiency in homogentisate 1,2-dioxygenase activity, leads to accumulation of oxidised homogentisic acid in cartilage and collagenous structures present in all organs
Externí odkaz:
https://doaj.org/article/082681620fef4f64859f18f7f351bba9
Autor:
Claudia Lentucci, ini, Maurizio Orl, Francesca Anselmi, Federico Galvagni, Francesco Neri, Caterina De Clemente
Publikováno v:
Journal of Stem Cell Research & Therapy.
Objective:Embryonic stem cells (ESC) pluripotency is maintained through a complex interplay of different signaling pathways and a network of transcription factors. Although much is known about this pluripotency selfrenewal circuitry, the molecular ev
Autor:
Vittoria Cicaloni, Malancha Karmakar, Luisa Frusciante, Francesco Pettini, Anna Visibelli, Maurizio Orlandini, Federico Galvagni, Maurizio Mongiat, Michael Silk, Federica Nardi, David Ascher, Annalisa Santucci, Ottavia Spiga
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
The transmembrane glycoprotein CD93 has been identified as a potential new target to inhibit tumor angiogenesis. Recently, Multimerin-2 (MMRN2), a pan-endothelial extracellular matrix protein, has been identified as a ligand for CD93, but the interac
Externí odkaz:
https://doaj.org/article/06e83d3eadc84805a034ceb8e0e899cd
Autor:
Stefano Barbera, Federica Nardi, Ines Elia, Giulia Realini, Roberta Lugano, Annalisa Santucci, Gian Marco Tosi, Anna Dimberg, Federico Galvagni, Maurizio Orlandini
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background In the endothelium, the single-pass membrane protein CD93, through its interaction with the extracellular matrix protein Multimerin-2, activates signaling pathways that are critical for vascular development and angiogenesis. Traff
Externí odkaz:
https://doaj.org/article/7afec69c17a14693a4779c02951cc699
Autor:
Lia Millucci, Mariagiulia Minetti, Maurizio Orlandini, Daniela Braconi, Maria Lucia Schiavone, Silvia Galderisi, Barbara Marzocchi, Ottavia Spiga, Roberto Rappuoli, Adriano Spreafico, Giuseppe Perretti, Giulia Bernardini, Annalisa Santucci
Publikováno v:
Journal of Functional Foods, Vol 54, Iss , Pp 109-118 (2019)
Silicon (Si) is an essential element for bone metabolism and beer is one of the richest sources of orthosilicic acid (OSA), the readily bioavailable form of Si. In this work, we compared the in vitro pro-anabolic effects on human osteoblastic cells o
Externí odkaz:
https://doaj.org/article/bd896f167921425da03f59f63974da45
Autor:
Stefano Barbera, Luisa Raucci, Roberta Lugano, Gian Marco Tosi, Anna Dimberg, Annalisa Santucci, Federico Galvagni, Maurizio Orlandini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12417 (2021)
During angiogenesis, cell adhesion molecules expressed on the endothelial cell surface promote the growth and survival of newly forming vessels. Hence, elucidation of the signaling pathways activated by cell-to-matrix adhesion may assist in the disco
Externí odkaz:
https://doaj.org/article/e6c7b607c7ed4b4281652e459054c523
Autor:
Lucia Mundo, Gian Marco Tosi, Stefano Lazzi, Grazia Pertile, Barbara Parolini, Giovanni Neri, Matteo Posarelli, Elena De Benedetto, Tommaso Bacci, Ennio Silvestri, Maria Chiara Siciliano, Stefano Barbera, Maurizio Orlandini, John Greenwood, Stephen E. Moss, Federico Galvagni
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8879 (2021)
Leucine-rich a-2-glycoprotein 1 (LRG1) is a candidate therapeutic target for treating the neovascular form of age-related macular degeneration (nvAMD). In this study we examined the expression of LRG1 in eyes of nvAMD patients. Choroidal neovascular
Externí odkaz:
https://doaj.org/article/8eba60aa9f524468b6af39d367242a55
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 645 (2021)
Bile acids (BAs) are hydroxylated steroids derived from cholesterol that act at the intestinal level to facilitate the absorption of several nutrients and also play a role as signaling molecules. In the liver of various vertebrates, the trafficking o
Externí odkaz:
https://doaj.org/article/d5db4fcd2e504a6caad565d05fa00249
Autor:
Gian Marco Tosi, Daniela Giustarini, Lorenzo Franci, Alberto Minetti, Francesco Imperatore, Elena Caldi, Paolo Fiorenzani, Anna Maria Aloisi, Anna Sparatore, Ranieri Rossi, Mario Chiariello, Maurizio Orlandini, Federico Galvagni
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 600 (2021)
Oxidative stress plays a key role in the pathophysiology of retinal diseases, including age-related macular degeneration (AMD) and diabetic retinopathy, which are the major causes of irreversible blindness in developed countries. An excess of reactiv
Externí odkaz:
https://doaj.org/article/a113fa99f4a243d781610419bcc4a740
Autor:
Ottavia Spiga, Vittoria Cicaloni, Anna Visibelli, Alessandro Davoli, Maria Ausilia Paparo, Maurizio Orlandini, Barbara Vecchi, Annalisa Santucci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1187 (2021)
ApreciseKUre is a multi-purpose digital platform facilitating data collection, integration and analysis for patients affected by Alkaptonuria (AKU), an ultra-rare autosomal recessive genetic disease. It includes genetic, biochemical, histopathologica
Externí odkaz:
https://doaj.org/article/8c0f7dd42e4a44b79317bd205c427bbc