Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Maurizio Ceruti"'
Autor:
Roberta Cavalli, Paola Brusa, Maurizio Ceruti, Simona Sapino, Paola Milla, Luigi Battaglia, Barbara Stella, Franco Dosio, Elena Peira, Marina Gallarate, Silvia Arpicco, Elena Ugazio, Daniela Chirio, Flavio Rocco
Publikováno v:
Journal of Drug Delivery Science and Technology. 32:298-312
Some approaches to enhance the entrapment efficiency within nanoparticulate systems, chiefly of hydrophilic molecules, developed mainly by the Turin University Pharmaceutical Technology group, are discussed. Several approaches have been developed: th
Autor:
Cinzia Scialabba, Gaetano Giammona, Nicolò Mauro, Mariano Licciardi, Maurizio Ceruti, Flavio Rocco
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 88:695-705
This paper deal with the synthesis and characterization of PEGylated squalene-grafted-inulin amphiphile capable of self-assembling and self-organizing into nanocarriers once placed in aqueous media. It was exploited as coating agent for obtaining dox
Autor:
Gaetano Giammona, Cinzia Scialabba, Giovanna Pitarresi, Flavio Rocco, Mariano Licciardi, Maurizio Ceruti
Publikováno v:
Drug Delivery. 19:307-316
A novel polysorbate-80 (PS(80))-attached amphiphilic copolymer comprising a hydrophilic α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA) backbone and hydrophobic squalenyl-C(17) (Sq(17)) portions was synthesized and characterized; the formation of
Publikováno v:
International Journal of Pharmaceutics. 382:73-79
Differential scanning calorimetry was used to study the interaction of acyclovir and its prodrug squalenoyl-acyclovir (obtained by conjugation of 1,1',2-tris-nor-squalene acid (squaleneCOOH) with acyclovir) with biomembrane models made of DMPC multil
Autor:
Maria Grazia Sarpietro, Samuele Voyron, Valeria Filipello Marchisio, Alessandra Fiorio Pla, Giovanna Cristina Varese, Flavio Rocco, Paolo E. Forni, Maurizio Ceruti
Publikováno v:
Mycoses. 53:481-487
The antifungal activity and in vitro toxicity toward animal cells of two inhibitors of oxidosqualene cyclase, squalene bis-diethylamine (SBD) and squalene bis-diethylmethylammonium iodide (SBDI) were studied. Minimum inhibitory concentration (MIC) ag
Autor:
Gianni Balliano, Flavio Rocco, A. Lenhart, Francesco Castelli, Paola Milla, Maurizio Ceruti, Georg E. Schulz
Publikováno v:
Lipids. 40:729-735
New iodoacetamide derivatives, containing a dodecyl or a squalenyl moiety, were synthesized. The effect of these new thiol-reacting molecules was studied on two mutants of Alicyclobacillus acidocaldarius squalene-hopene cyclase constructed especially
Autor:
William K. Wilson, Quanbo Xiong, Ran Xu, Maurizio Ceruti, Seiichi P. T. Matsuda, Flavio Rocco
Publikováno v:
The Journal of Organic Chemistry. 70:5362-5375
[reaction: see text] The dammarenyl cation (13) is the last common intermediate in the cyclization of oxidosqualene to a diverse array of secondary triterpene metabolites in plants. We studied the structure and reactivity of 13 to understand the fact
Publikováno v:
Scopus-Elsevier
Many attempts have been made to achieve good selectivity to targeted tumor cells by preparing specialized carrier agents that are therapeutically profitable for anticancer therapy. Among these, liposomes are the most studied colloidal particles thus
Autor:
Barbara Stella, Franco Dosio, Silvia Arpicco, Paola Brusa, Maurizio Ceruti, Chiara Lubelli, Luigi Cattel, Andrea Bolognesi
Publikováno v:
Bioconjugate Chemistry. 13:757-765
This study describes the synthesis, characterization, and reactivity of new methoxypoly(ethylene glycol) (mPEG) derivatives containing a thioimidoester reactive group. These activated polymers are able to react with the lysyl epsilon-amino groups of