Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maurizio Maio"'
Autor:
Anthony Nichols, David Covini, Anna Quattropani, Jean-François Arrighi, Yves Cambet, Maurizio Maio, Thierry Martin, Olivier Schott, Bernard Françon, Laurence Novo-Perez, Don Simpson, Delphine Marin, Delphine Rivron, Cristina Donini, Agnes Bombrun, Pierre-Alain Vitte, Stefano Crosignani, Wolfgang H. B. Sauer, Isabelle Martinou, Dominique Swinnen, Valerie Eligert, Fabienne Burgat-Charvillon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1516-1519
The discovery of a novel series of S1P1 agonists is described. Starting from a micromolar HTS positive, iterative optimization gave rise to several single-digit nanomolar S1P1 agonists. The compounds were able to induce internalization of the S1P1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016d011f2a43aa5c6d794dc932148d8b
https://doi.org/10.1016/j.bmcl.2010.01.102
https://doi.org/10.1016/j.bmcl.2010.01.102
Autor:
Alexander Scheer, Jean-François Arrighi, Lucia Golzio, Marc Missotten, Yaroslav Filinchuk, Véronique Colovray, Pierre-André Pittet, Christophe Cleva, André Chollet, Thierry Martin, Atherall John Frederick, Claudio Giachetti, Maurizio Maio, Cynthia Rocha, Matthias Schwarz, Jackie Macritchie, Patrick Page, Gérald Bernardinelli, Stefano Crosignani, Yves Humbert, Doris Pupowicz, Marilène Gaudet
Publikováno v:
Journal of medicinal chemistry. 51(7)
A novel chemical class of potent chemoattractant receptor-homologous expressed on Th2 lymphocytes (CRTH2 or DP2) antagonists is reported. An initial and moderately potent spiro-indolinone compound (5) was found during a high-throughput screening camp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9569591f6a7caff3d3dccb696fa37a
https://pubmed.ncbi.nlm.nih.gov/18318469
https://pubmed.ncbi.nlm.nih.gov/18318469
Autor:
Stefano Crosignani, Patrick Page, Marc Missotten, Véronique Colovray, Christophe Cleva, Jean-François Arrighi, John Atherall, Jackie Macritchie, Thierry Martin, Yves Humbert, Marilène Gaudet, Doris Pupowicz, Maurizio Maio, Pierre-André Pittet, Lucia Golzio, Claudio Giachetti, Cynthia Rocha, Gérald Bernardinelli, Yaroslav Filinchuk, Alexander Scheer
Publikováno v:
Journal of Medicinal Chemistry; Mar2008, Vol. 51 Issue 7, p2227-2243, 17p