Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Maurizio, Paci"'
Autor:
Enrico Garaci, Maurizio Paci, Claudia Matteucci, Claudio Costantini, Paolo Puccetti, Luigina Romani
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Phenotypic drug discovery (PDD) involves screening compounds for their effects on cells, tissues, or whole organisms without necessarily understanding the underlying molecular targets. PDD differs from target-based strategies as it does not require k
Externí odkaz:
https://doaj.org/article/ace5ad83713d4462b1a644ba82daee81
Autor:
Claudia Matteucci, Ridvan Nepravishta, Ayele Argaw-Denboba, Walter Mandaliti, Alessandro Giovinazzo, Vita Petrone, Emanuela Balestrieri, Paola Sinibaldi-Vallebona, Francesca Pica, Maurizio Paci, Enrico Garaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06daa9a5f637fa60a73d7ea2ad1816b6
https://hdl.handle.net/2108/324163
https://hdl.handle.net/2108/324163
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 180K, MCT-1 up-regulation induced by glutamine deprivation is responsible for 3-BrPA chemo-potentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc26b52f36ac3e60bc7cbdf685572aa
https://doi.org/10.1158/0008-5472.22394070
https://doi.org/10.1158/0008-5472.22394070
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 211K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9533792346d257423284eb540ec7bc
https://doi.org/10.1158/0008-5472.22394061.v1
https://doi.org/10.1158/0008-5472.22394061.v1
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
Anticancer drug efficacy might be leveraged by strategies to target certain biochemical adaptations of tumors. Here we show how depriving cancer cells of glutamine can enhance the anticancer properties of 3-bromopyruvate, a halogenated analog of pyru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b4fd296eb40f769a1e274082d9824d6
https://doi.org/10.1158/0008-5472.c.6503940.v1
https://doi.org/10.1158/0008-5472.c.6503940.v1
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 77K, Glutamine-deprivation up-regulates MCT-1 levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af29a1afbf4d50b5ab2a79b7289cd2d3
https://doi.org/10.1158/0008-5472.22394073
https://doi.org/10.1158/0008-5472.22394073
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 98K, Complex II inhibition is responsible for 3-BrPA-induced metabolic-oxidative stress upon glutamine deprivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cc11485b189b49e185688719470941
https://doi.org/10.1158/0008-5472.22394076
https://doi.org/10.1158/0008-5472.22394076
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 147K, Autophagy contributes to the execution of 3-BrPA-induced cell death upon glutamine withdrawal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1130e1909aa858787f2acb955a37483f
https://doi.org/10.1158/0008-5472.22394085
https://doi.org/10.1158/0008-5472.22394085
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 154K, Glutamine deprivation-induced 3-BrPA chemo-potentiation does not depend on synergistic impairment of glutaminolysis and glycolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b8ab42ea7867fa2578004f5e97d111
https://doi.org/10.1158/0008-5472.22394082.v1
https://doi.org/10.1158/0008-5472.22394082.v1
Autor:
Maria Rosa Ciriolo, Giuseppe Rotilio, Maurizio Paci, Maurizio Mattei, Fabio Bertocchi, Roberta Bernardini, Giuseppe Filomeni, Salvatore Rizza, Simone Cardaci
PDF file - 127K, Chemo-potentiation of 3-BrPA cytotoxicity is not associated with the activation of apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a23023b2a30d3bfe5d7c90bde3b40e9
https://doi.org/10.1158/0008-5472.22394088
https://doi.org/10.1158/0008-5472.22394088