Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maurits Roorda"'
Autor:
Dario Zimmerli, Chiara S. Brambillasca, Francien Talens, Jinhyuk Bhin, Renske Linstra, Lou Romanens, Arkajyoti Bhattacharya, Stacey E. P. Joosten, Ana Moises Da Silva, Nuno Padrao, Max D. Wellenstein, Kelly Kersten, Mart de Boo, Maurits Roorda, Linda Henneman, Roebi de Bruijn, Stefano Annunziato, Eline van der Burg, Anne Paulien Drenth, Catrin Lutz, Theresa Endres, Marieke van de Ven, Martin Eilers, Lodewyk Wessels, Karin E. de Visser, Wilbert Zwart, Rudolf S. N. Fehrmann, Marcel A. T. M. van Vugt, Jos Jonkers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tripe-negative breast cancers poorly respond to immune checkpoint inhibition therapy, due to their immune-hostile tumour microenvironment. Authors here show that the oncogene MYC plays a pivotal role in suppressing anti-tumour immunity via directly r
Externí odkaz:
https://doaj.org/article/07f7321be51a4bf993332239abb08b2b
Autor:
Lin Zhou, Siqi Zheng, Fernando R Rosas Bringas, Bjorn Bakker, Judith E Simon, Petra L Bakker, Hinke G Kazemier, Michael Schubert, Maurits Roorda, Marcel A T M van Vugt, Michael Chang, Floris Foijer
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
AbstractMaternal embryonic leucine zipper kinase (MELK) is frequently overexpressed in cancer, but the role of MELK in cancer is still poorly understood. MELK was shown to have roles in many cancer-associated processes including tumor growth, chemoth
Externí odkaz:
https://doaj.org/article/47ad807053204d65be2ed713aa553e49
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101961- (2021)
Hydrogen sulfide (H2S) has long been recognized as a putrid, toxic gas. However, as a result of intensive biochemical research in the past two decades, H2S is now considered to be the third gasotransmitter alongside nitric oxide (NO) and carbon monox
Externí odkaz:
https://doaj.org/article/3ebf2875919644a4bca029272e3470fb
Autor:
Christy Hong, Michael Schubert, Andréa E. Tijhuis, Marta Requesens, Maurits Roorda, Anouk van den Brink, Lorena Andrade Ruiz, Petra L. Bakker, Tineke van der Sluis, Wietske Pieters, Mengting Chen, René Wardenaar, Bert van der Vegt, Diana C. J. Spierings, Marco de Bruyn, Marcel A. T. M. van Vugt, Floris Foijer
Publikováno v:
Nature, 607, 366-373. Nature Publishing Group
Chromosomal instability (CIN) drives cancer cell evolution, metastasis and therapy resistance, and is associated with poor prognosis1. CIN leads to micronuclei that release DNA into the cytoplasm after rupture, which triggers activation of inflammato
Autor:
Christy, Hong, Michael, Schubert, Andréa E, Tijhuis, Marta, Requesens, Maurits, Roorda, Anouk, van den Brink, Lorena Andrade, Ruiz, Petra L, Bakker, Tineke, van der Sluis, Wietske, Pieters, Mengting, Chen, René, Wardenaar, Bert, van der Vegt, Diana C J, Spierings, Marco, de Bruyn, Marcel A T M, van Vugt, Floris, Foijer
Publikováno v:
Nature. 607(7918)
Chromosomal instability (CIN) drives cancer cell evolution, metastasis and therapy resistance, and is associated with poor prognosis
Autor:
Maurits Roorda, Michael Schubert, Petra L. Bakker, Michael Chang, Marcel A. T. M. van Vugt, Bjorn Bakker, Lin Zhou, Judith E Simon, Hinke G. Kazemier, Fernando R. Rosas Bringas, Siqi Zheng, Floris Foijer
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
G3 : Genes, Genomes, Genetics, 11(12):335. GENETICS SOCIETY AMERICA
G3: Genes|Genomes|Genetics
G3 : Genes, Genomes, Genetics, 11(12):335. GENETICS SOCIETY AMERICA
G3: Genes|Genomes|Genetics
Maternal embryonic leucine zipper kinase (MELK) is frequently overexpressed in cancer, but the role of MELK in cancer is still poorly understood. MELK was shown to have roles in many cancer-associated processes including tumor growth, chemotherapy re
Autor:
Michael Schubert, Bjorn Bakker, Fernando R. Rosas Bringas, Siqi Zheng, Floris Foijer, Petra L. Bakker, Lin Zhou, Maurits Roorda, Hinke G. Kazemier, Marcel A. T. M. van Vugt, Michael Chang, Judith E Simon
Maternal embryonic leucine zipper kinase (MELK) is frequently overexpressed in cancer, but the role of MELK in cancer is still poorly understood. MELK was shown to have roles in many cancer-associated processes including tumor growth, chemotherapy re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e37de8eaf5215e410df674114149d3
https://doi.org/10.1101/2021.07.16.452653
https://doi.org/10.1101/2021.07.16.452653
Publikováno v:
Redox Biology, Vol 43, Iss, Pp 101961-(2021)
Redox Biology
Redox Biology
Hydrogen sulfide (H2S) has long been recognized as a putrid, toxic gas. However, as a result of intensive biochemical research in the past two decades, H2S is now considered to be the third gasotransmitter alongside nitric oxide (NO) and carbon monox
Autor:
Maurits Roorda, Edwin L de Vrij, P. Vogelaar, Guido Krenning, Hjalmar R. Bouma, M. C. Houwertjes, Adrianus Cornelis Van Der Graaf, Robert H. Henning, Maaike Goris
Publikováno v:
Nephrology, Dialysis, Transplantation, 33(12), 2128-2138. Oxford University Press
Background. Mitochondrial dysfunction plays an important role in kidney damage in various pathologies, including acute and chronic kidney injury and diabetic nephropathy. In addition to the well-studied ischaemia/reperfusion (I/R) injury, hypothermia
Autor:
Ana Moises Da Silva, Stacey E. P. Joosten, Jinhyuk Bhin, Marcel A. T. M. van Vugt, Maurits Roorda, Wilbert Zwart, Anne Paulien Drenth, Chiara S. Brambillasca, Roebi de Bruijn, Lodewyk F. A. Wessels, Rudolf S N Fehrmann, Catrin Lutz, Linda Henneman, Arkajyoti Bhattacharya, Dario Zimmerli, Eline van der Burg, Jos Jonkers, Max D. Wellenstein, Marieke van de Ven, Karin E. de Visser, Francien Talens, Stefano Annunziato, Mart de Boo, Kelly Kersten
Immune checkpoint inhibitor (ICI) treatment has thus far shown limited efficacy in triple-negative breast cancer (TNBC) patients, presumably due to sparse or unresponsive tumor-infiltrating lymphocytes. We reveal a strong correlation between MYC expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1a3a50f12778f74686f5c57e2768675
https://doi.org/10.1101/2021.02.24.432659
https://doi.org/10.1101/2021.02.24.432659