Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maurits Geert Laurent Olthof"'
Autor:
Michael J. Yaszemski, Lichun Lu, Maurits Geert Laurent Olthof, Mahrokh Dadsetan, Marianna A. Tryfonidou, Diederik H.R. Kempen, Wouter J.A. Dhert
Publikováno v:
Tissue Engineering Part C: Methods. 24:379-390
Local sustained delivery of bioactive molecules from biomaterials is a promising strategy to enhance bone regeneration. To optimize delivery vehicles for bone formation, the design characteristics are tailored with consequential effect on bone morpho
Autor:
Mahrokh Dadsetan, Kristen L. Shogren, Maurits Geert Laurent Olthof, Andre J. van Wijnen, Michael J. Yaszemski, Sanjeev Kakar, Joshua A Parry
Publikováno v:
Tissue Engineering Part A. 23:359-365
Anterior cruciate ligament (ACL) ruptures reconstructed with tendon grafts are commonly fixed with bioabsorbable implants, which are frequently complicated by incomplete bone filling upon degradation. Bone regeneration after ACL reconstruction could
Autor:
Wouter J.A. Dhert, Michael J. Yaszemski, Lichun Lu, James L. Herrick, Maurits Geert Laurent Olthof, Diederik H.R. Kempen
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:477-487
To investigate the effect of sustained bone morphogenetic protein-2 (BMP-2) release kinetics on bone formation in poly(propylene fumarate) (PPF) scaffolds, different poly(lactic-co-glycolic acid) (PLGA) microspheres were used as delivery vehicles. Al
Autor:
Diederik H.R. Kempen, Lichun Lu, Marianna A. Tryfonidou, Xifeng Liu, Mahrokh Dadsetan, Michael J. Yaszemski, Maurits Geert Laurent Olthof, Wouter J.A. Dhert
Publikováno v:
Tissue Eng Part A
Biomaterials that act as both protein delivery vehicle and scaffold can improve the safety and efficacy of bone morphogenetic protein-2 (BMP-2) for clinical applications. However, the optimal scaffold characteristics are not known. The osteoinductive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ca80a459108540ac8f1359c8c8bd01
https://europepmc.org/articles/PMC6648221/
https://europepmc.org/articles/PMC6648221/
Autor:
Diederik H.R. Kempen, Michael J. Yaszemski, Marianna A. Tryfonidou, Björn P. Meij, Lichun Lu, Jacqueline Alblas, Loek D. Loozen, Behdad Pouran, Wouter J.A. Dhert, Maurits Geert Laurent Olthof
Publikováno v:
Tissue Engineering-Part A, 25(3-4), 193. Mary Ann Liebert Inc.
The main challenge in bone morphogenic protein 2 (BMP-2)-based application lies in finding strategies that prolong its effective period as it has a short biological half-life. Several BMP-2 release profiles have shown to enhance bone formation at var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e9932851808792bd2b1b0acfc127b6
https://dspace.library.uu.nl/handle/1874/385587
https://dspace.library.uu.nl/handle/1874/385587
Autor:
Jacqueline Alblas, Marianna A. Tryfonidou, Behdad Pouran, Lichun Lu, Diederik H.R. Kempen, Michael J. Yaszemski, Björn P. Meij, Xifeng Liu, Maurits Geert Laurent Olthof, Wouter J.A. Dhert
Publikováno v:
Tissue Engineering-Part A, 24(9-10), 819. Mary Ann Liebert Inc.
Off-the-shelf availability in large quantities, drug delivery functionality, and modifiable chemistry and mechanical properties make synthetic polymers highly suitable candidates for bone grafting. However, most synthetic polymers lack the ability to