Evolution of Gene Expression in the Uterine Cervix related to Steroid Signaling: Conserved features in the regulation of cervical ripening

Autor: Günter P. Wagner, Mauris C. Nnamani, Arun Rajendra Chavan, Jamie Maziarz, Stella Protopapas, Jennifer Condon, Roberto Romero

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Abstract The uterine cervix is the boundary structure between the uterus and the vagina and is key for the maintenance of pregnancy and timing of parturition. Here we report on a comparative transcriptomic study of the cervix of four placental mammal

Externí odkaz: https://doaj.org/article/c3705a7f926246be8479a8c34ec3cb98

The mammalian decidual cell evolved from a cellular stress response.

Autor: Eric M Erkenbrack, Jamie D Maziarz, Oliver W Griffith, Cong Liang, Arun R Chavan, Mauris C Nnamani, Günter P Wagner

Publikováno v: PLoS Biology, Vol 16, Iss 8, p e2005594 (2018)

Among animal species, cell types vary greatly in terms of number and kind. The number of cell types found within an organism differs considerably between species, and cell type diversity is a significant contributor to differences in organismal struc

Externí odkaz: https://doaj.org/article/a32b6f99fceb42d6a98d1a051344f6ec

Ancient Transposable Elements Transformed the Uterine Regulatory Landscape and Transcriptome during the Evolution of Mammalian Pregnancy

Autor: Vincent J. Lynch, Mauris C. Nnamani, Aurélie Kapusta, Kathryn Brayer, Silvia L. Plaza, Erik C. Mazur, Deena Emera, Shehzad Z. Sheikh, Frank Grützner, Stefan Bauersachs, Alexander Graf, Steven L. Young, Jason D. Lieb, Francesco J. DeMayo, Cédric Feschotte, Günter P. Wagner

Publikováno v: Cell Reports, Vol 10, Iss 4, Pp 551-561 (2015)

A major challenge in biology is determining how evolutionarily novel characters originate; however, mechanistic explanations for the origin of new characters are almost completely unknown. The evolution of pregnancy is an excellent system in which to

Externí odkaz: https://doaj.org/article/160dd80e03d34e2d89920f43dc99d149

Genetic Associations With Gestational Duration and Spontaneous Preterm Birth

Autor: David A. Hinds, Bjarke Feenstra, Bo Jacobsson, Nadia K. Litterman, Mika Rämet, Kelli K Ryckman, Lisa M. Muglia, Youna Hu, Jamie Maziarz, Minna K. Karjalainen, Leah C. Kottyan, Carmy Forney, Mauris C. Nnamani, Daniel Miller, Johanna M. Huusko, Matthew T. Weirauch, Ellen A. Nohr, Allison Momany, George Davey Smith, Frank Geller, Xueping Liu, Bruce Bedell, Aarno Palotie, Mihaela Pavlicev, Arun R. Chavan, Louis J. Muglia, Pan Pan Jiang, Kari Teramo, Heather A. Boyd, Mads Melbye, Mikko Hallman, Verena Sengpiel, Günter P. Wagner, Julius Juodakis, Xiaoting Chen, Jonas Bacelis, Ge Zhang, Laura Russell

Publikováno v: Zhang, G, Feenstra, B, Bacelis, J, Liu, X, Muglia, L M, Juodakis, J, Miller, D E, Litterman, N, Jiang, P-P, Russell, L, Hinds, D A, Hu, Y, Weirauch, M T, Chen, X, Chavan, A R, Wagner, G P, Pavličev, M, Nnamani, M C, Maziarz, J, Karjalainen, M K, Rämet, M, Sengpiel, V, Geller, F, Boyd, H A, Palotie, A, Momany, A, Bedell, B, Ryckman, K K, Huusko, J M, Forney, C R, Kottyan, L C, Hallman, M, Teramo, K, Nohr, E A, Davey Smith, G, Melbye, M, Jacobsson, B & Muglia, L J 2017, ' Genetic Associations with Gestational Duration and Spontaneous Preterm Birth ', The New England Journal of Medicine, vol. 377, no. 12, pp. 1156-1167 . https://doi.org/10.1056/NEJMoa1612665
Zhang, G, Feenstra, B, Bacelis, J, Liu, X, Muglia, L M, Juodakis, J, Litterman, N, Hinds, D A, Hu, Y, Weirauch, M T, Chen, X, Chavan, A R, Wagner, G P, Pavličev, M, Nnamani, M C, Maziarz, J, Karjalainen, M K, Rämet, M, Sengpiel, V, Geller, F, Boyd, H A, Palotie, A, Momany, A, Bedell, B, Ryckman, K K, Huusko, J M, Forney, C R, Kottyan, L C, Hallman, M, Teramo, K, Nohr, E A, Smith, G D, Melbye, M, Jacobsson, B & Muglia, L J 2017, ' Genetic associations with gestational duration and spontaneous preterm birth ', New England Journal of Medicine, vol. 377, no. 12, pp. 1156-1167 . https://doi.org/10.1056/NEJMoa1612665
The New England Journal of Medicine
Zhang, G, Feenstra, B, Bacelis, J, Liu, X, Muglia, L M, Juodakis, J, Miller, D E, Litterman, N, Jiang, P P, Russell, L, Hinds, D A, Hu, Y, Weirauch, M T, Chen, X, Chavan, A R, Wagner, G P, Pavličev, M, Nnamani, M C, Maziarz, J, Karjalainen, M K, Ramet, M, Sengpiel, V, Geller, F, Boyd, H A, Palotie, A, Momany, A, Bedell, B, Ryckman, K K, Huusko, J M, Forney, C R, Kottyan, L C, Hallman, M, Teramo, K, Nohr, E A, Davey Smith, G, Melbye, M, Jacobsson, B & Muglia, L J 2018, ' Genetic Associations with Gestational Duration and Spontaneous Preterm Birth ', Obstetrical and Gynecological Survey, vol. 73, no. 2, pp. 83-85 . https://doi.org/10.1097/01.ogx.0000530434.15441.45

Background: Despite evidence that genetic factors contribute to the duration of gestation and the risk of preterm birth, robust associations with genetic variants have not been identified. We used large data sets that included the gestational duratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c91222807de9a168bf9bb010ac555b
https://doi.org/10.1097/01.ogx.0000530434.15441.45

The mammalian decidual cell evolved from a cellular stress response

Autor: Jamie Maziarz, Arun R. Chavan, Oliver W. Griffith, Cong Liang, Eric M. Erkenbrack, Mauris C. Nnamani, Günter P. Wagner

Publikováno v: PLoS Biology, Vol 16, Iss 8, p e2005594 (2018)

Among animal species, cell types vary greatly in terms of number and kind. The number of cell types found within an organism differs considerably between species, and cell type diversity is a significant contributor to differences in organismal struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82791287e9b2ad54c05b92003c03dc5c
http://europepmc.org/articles/PMC6108454?pdf=render