Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maurine Braun"'
Autor:
Yuanjing Liu, Jean-Cosme Dodart, Helene Tran, Shaunna Berkovitch, Maurine Braun, Michael Byrne, Ann F. Durbin, Xiao Shelley Hu, Naoki Iwamoto, Hyun Gyung Jang, Pachamuthu Kandasamy, Fangjun Liu, Kenneth Longo, Jörg Ruschel, Juili Shelke, Hailin Yang, Yuan Yin, Amy Donner, Zhong Zhong, Chandra Vargeese, Robert H. Brown
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
C9orf72 expansion mutations are the most common genetic cause of ALS and FTD, which have limited therapies. The authors generate stereopure oligonucleotides that selectively deplete expansion-containing transcripts and protect against expansion-assoc
Externí odkaz:
https://doaj.org/article/c67a2cf526554819ac5be15eaecb07de
Autor:
Pachamuthu Kandasamy, Ann Fiegen Durbin, Michael Byrne, Robert H. Brown, Jean-Cosme Dodart, Yuan Yin, Kenneth Longo, Amy Donner, Fangjun Liu, Xiao Shelley Hu, Naoki Iwamoto, Juili Dilip Shelke, Maurine Braun, Chandra Vargeese, Jörg Ruschel, Hailin Yang, Helene Tran, Shaunna Berkovitch, Yuanjing Liu, Zhong Zhong, Hyun Gyung Jang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
A large G4C2-repeat expansion in C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Neuronal degeneration associated with this expansion arises from a loss of C9orf72 protein, the accumu
Autor:
Abhishek Chiyyeadu, Maurine Braun, Claudia Harper, Christopher E. Mason, Christine Oborski, Daniella Pizzurro, Axel Schambach, Niek P. van Til, Bianling Liu, John K. Yoon, Yildirim Dogan, Richard Pfeifer, Swaroopa Guda, Cecilia Barese, Zeenath Unnisa, Mary Jacobs, Rena Schindler
Publikováno v:
Molecular Genetics and Metabolism. 132:S107
Autor:
Robert H. Brown, Jason K. Kim, Alexandra Castillo-Ruiz, William J. Schwartz, Maurine Braun, Steven J. Swoap, Premananda Indic, Dae Young Jung
Publikováno v:
Experimental neurology. 311
Current understanding of the pathogenesis of the familial form of amyotrophic lateral sclerosis has been aided by the study of transgenic mice that over-express mutated forms of the human CuZn-superoxide dismutase (SOD1) gene. While mutant SOD1 in mo
Autor:
Kenneth Longo, Hailin Yang, Maria Frank-Kamenetsky, Genliang Lu, Keith Bowman, Lynnelle Pittet, Sethu Menon, Naoki Iwamoto, Jason Jingxin Zhang, Vincent Aduda, David Butler, Zhong Zhong, Yuan Yin, Luciano H. Apponi, Maurine Braun, Anee Shah, Stephany Michelle Standley, Chandra Vargeese
Publikováno v:
Gastroenterology. 154:S-1122