Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Mauricio Torres"'
Autor:
Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson, Xiaoqiong Wei, Mauricio Torres, You Lu, Zexin Jason Li, Xiaodan Liu, Hancheng Mao, Hui Wang, Linyao Elina Zhou, Zhen Zhao, Shengyi Sun, Ling Qi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The SEL1L-HRD1 protein complex represents the most conserved branch of endoplasmic reticulum (ER)-associated degradation (ERAD). Despite recent advances in both mouse models and humans, in vivo evidence for the importance of SEL1L in the ERA
Externí odkaz:
https://doaj.org/article/014892729fb04bc09af72c00d188ae38
Publikováno v:
The Lancet Regional Health. Americas, Vol 34, Iss , Pp 100739- (2024)
Externí odkaz:
https://doaj.org/article/61ab74d76e354a69a75aaf251ff20831
Autor:
Shuangcheng Alivia Wu, Chenchen Shen, Xiaoqiong Wei, Xiawei Zhang, Siwen Wang, Xinxin Chen, Mauricio Torres, You Lu, Liangguang Leo Lin, Huilun Helen Wang, Allen H. Hunter, Deyu Fang, Shengyi Sun, Magdalena I. Ivanova, Yi Lin, Ling Qi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Endoplasmic reticulum (ER)-associated degradation (ERAD) and ER-phagy are two principal degradative mechanisms for ER proteins and aggregates, respectively; however, the crosstalk between these two pathways under physiological settings remai
Externí odkaz:
https://doaj.org/article/55b8edfe9e8d440db2033fcd22bb16d0
Publikováno v:
Chemistry, Vol 5, Iss 1, Pp 559-570 (2023)
In the design and fabrication of any structural system for space application, balance between mass, stiffness and strength is crucial. Structures in space environments are exposed to high radiation levels and thermal shock, due to the sun irradiance
Externí odkaz:
https://doaj.org/article/937aeca29d4e40febf04f07a545787a2
Autor:
Carmen Liy-Wong, Cristina Tarango, Elena Pope, Thomas Coates, Anna L. Bruckner, James A. Feinstein, Agnes Schwieger-Briel, Lynne D. Hubbard, Clapham Jane, Mauricio Torres-Pradilla, Matija Zmazek, Irene Lara-Corrales
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background Anemia is a common complication of severe forms of epidermolysis bullosa (EB). To date, there are no guidelines outlining best clinical practices to manage anemia in the EB population. The objective of this manuscript is to presen
Externí odkaz:
https://doaj.org/article/d7872966dc354c4d80337276d308930c
Autor:
Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson, Xiaoqiong Wei, Mauricio Torres, You Lu, Zexin Jason Li, Xiaodan Liu, Hancheng Mao, Hui Wang, Linyao Elina Zhou, Zhen Zhao, Shengyi Sun, Ling Qi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/3b7bab21cbef4e3a961a981548530e88
Autor:
Benedict Abdon, Yusheng Liang, Débora da Luz Scheffer, Mauricio Torres, Neha Shrestha, Rachel B. Reinert, You Lu, Brent Pederson, Amara Bugarin-Lapuz, Sander Kersten, Ling Qi
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
The growth of skeletal muscle relies on a delicate equilibrium between protein synthesis and degradation; however, how proteostasis is managed in the endoplasmic reticulum (ER) is largely unknown. Here, we report that the SEL1L-HRD1 ER-associated deg
Externí odkaz:
https://doaj.org/article/3ffa758362b540b3be696ff228c0c6ab
Autor:
Mauricio Torres-Tovar
Publikováno v:
Revista Facultad Nacional de Salud Pública, Vol 41, Iss 3, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/5de4de9bf5594ef8ae796e28d5720a5b
Autor:
Xiaohan Zhang, Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Mauricio Torres, Yaron Tomer, Mihaela Stefan-Lifshitz, Hao Zhang, Dennis Larkin, Deyu Fang, Ling Qi, Peter Arvan
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Defects in endoplasmic reticulum (ER) proteostasis have been linked to diseases in multiple organ systems. Here we examined the impact of perturbation of ER proteostasis in mice bearing thyrocyte-specific knockout of either HRD1 (to disable ER-associ
Externí odkaz:
https://doaj.org/article/f043cf75429d4576b8f536e445366994
Autor:
Neha Shrestha, Mauricio Torres, Jason Zhang, You Lu, Leena Haataja, Rachel B. Reinert, Jeffrey Knupp, Yu-Jie Chen, Allen H. Hunter, Gunes Parlakgul, Ana Paula Arruda, Billy Tsai, Peter Arvan, Ling Qi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Three principal ER quality-control mechanisms, namely, the unfolded protein response, ER-associated degradation (ERAD), and ER-phagy are each important for the maintenance of ER homeostasis, yet how they are integrated to regulate ER homeostasis and
Externí odkaz:
https://doaj.org/article/7ed998726ce243deacfc094c1e0fad48