Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mauricio Navarro Villalobos"'
Autor:
Norberto Farfán, María Magdalena Vázquez-Alvarado, Mauricio Navarro Villalobos, Rosa Santillan, Blas Flores-Pérez, Oscar González-Antonio, Margarita Romero-Ávila
Publikováno v:
New Journal of Chemistry. 43:10491-10500
Delving into the scarcely explored versatility and selectivity of 4,7-dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine towards aromatic nucleophilic substitution, eleven new compounds were synthesized using different nucleophiles (alcohols, amines, and thio
Publikováno v:
Tetrahedron. 74:5085-5088
Described is a total synthesis of the related alkaloids, cyclopiamide A and speradine E, via a unified strategy that also delivers the natural product aspergilline A. Key steps include metal-free conversion of a malonyl chloride and propargylamine to
Publikováno v:
Organic Letters. 13:1110-1113
In this report, it is demonstrated that chiral vinyl aziridines can be stereospecifically ring expanded. This synthetic approach allows controlled access to chiral 2,5-cis- or 2,5-trans-3-pyrroline products from starting materials with the appropriat
Publikováno v:
Tetrahedron Letters. 50:6450-6453
Model studies towards the total synthesis of syringolides using a rhodium-catalyzed intramolecular C–H insertion reaction as the key step are described. A highly stereospecific synthesis of spirolactones is achieved employing this methodology.
Autor:
Catherine McCarty, Cristy Lindberg Benson, Mauricio Navarro Villalobos, Steven M. Zeman, Susan Jeong, John L. Wood, Matthew M. Weiss, Analee Salcedo, Jonathan Jenkins
Publikováno v:
Tetrahedron. 65:8091-8098
The first total syntheses of (−)-syringolide 3, (+)-syributin 3 and their unnatural enantiomers (+)-syringolide 3 and (−)-syributin 3 using a common intermediate as starting material are described. In addition, total syntheses of (−)- and (+)-s
Publikováno v:
ChemInform. 42
In this report, it is demonstrated that chiral vinyl aziridines can be stereospecifically ring expanded. This synthetic approach allows controlled access to chiral 2,5-cis- or 2,5-trans-3-pyrroline products from starting materials with the appropriat
Publikováno v:
Angewandte Chemie. 113:1162-1164
Publikováno v:
ChemInform. 32
Publikováno v:
ChemInform. 41
Model studies towards the total synthesis of syringolides using a rhodium-catalyzed intramolecular C–H insertion reaction as the key step are described. A highly stereospecific synthesis of spirolactones is achieved employing this methodology.
Autor:
David Y. Gin, Yong-Jae Kim, JohnMark Derryberry, Bridget D Rohde, Pengfei Wang, Mauricio Navarro-Villalobos
Publikováno v:
Journal of the American Chemical Society. 128(36)
QS-21 is one of the most promising new adjuvants for immune response potentiation and dose-sparing in vaccine therapy given its exceedingly high level of potency and its favorable toxicity profile. Melanoma, breast cancer, small cell lung cancer, pro