Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Mauricio J. Reginato"'
Autor:
Emily M. Esquea, Lorela Ciraku, Riley G. Young, Jessica Merzy, Alexandra N. Talarico, Nusaiba N. Ahmed, Mangalam Karuppiah, Anna Ramesh, Adam Chatoff, Claudia V. Crispim, Adel A. Rashad, Simon Cocklin, Nathaniel W. Snyder, Joris Beld, Nicole L. Simone, Mauricio J. Reginato, Alexej Dick
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Breast cancer brain metastasis (BCBM) typically results in an end-stage diagnosis and is hindered by a lack of brain-penetrant drugs. Tumors in the brain rely on the conversion of acetate to acetyl-CoA by the enzyme acetyl-CoA synthetase 2 (ACSS2), a
Externí odkaz:
https://doaj.org/article/4ae2b15c3c5446188251b5c916b863e7
Autor:
Giang Le Minh, Emily M. Esquea, Tejsi T. Dhameliya, Jessica Merzy, Mi-Hye Lee, Lauren E. Ball, Mauricio J. Reginato
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionBreast tumor development is regulated by a sub-population of breast cancer cells, termed cancer stem-like cells (CSC), which are capable of self-renewing and differentiating, and are involved in promoting breast cancer invasion, metastasi
Externí odkaz:
https://doaj.org/article/73855a2ba67f41b5b4633d4a716e2cac
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Altered metabolism and deregulated cellular energetics are now considered a hallmark of all cancers. Glucose, glutamine, fatty acids, and amino acids are the primary drivers of tumor growth and act as substrates for the hexosamine biosynthet
Externí odkaz:
https://doaj.org/article/28554646374447969a2d20a67e92cc3a
Autor:
Gregory P. Botta, Maximilian Reichert, Mauricio J. Reginato, Steffen Heeg, Anil K. Rustgi, Peter I. Lelkes
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 4, Pp 359-372 (2013)
Pancreatic ductal adenocarcinoma (PDAC) commonly contains a mutation in K-RasG12D and is characterized by a desmoplastic reaction composed of deregulated, proliferating cells embedded in an abnormal extracellular matrix (ECM). Our previous observatio
Externí odkaz:
https://doaj.org/article/81a32830787146f08ff9edeeb28a413b
AVI file - 30MB, Real-time imaging of invadapodial extensions into the ECM by E6/E7/Ras PDECs over 30 m.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a66ba07bc606191a91f728e5b58b1dd
https://doi.org/10.1158/1541-7786.22517887.v1
https://doi.org/10.1158/1541-7786.22517887.v1
Supplemental Figure 7: TGF-β1 induces EMT in NeuN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824cd25bd1a0bf5378ae25726d5d4606
https://doi.org/10.1158/1541-7786.22514256.v1
https://doi.org/10.1158/1541-7786.22514256.v1
Supplemental Figure 2: Levels of CXCR4 and CXCL12 in NeuT and NeuN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f12d094f98d9c87e6e680294958945a
https://doi.org/10.1158/1541-7786.22514271.v1
https://doi.org/10.1158/1541-7786.22514271.v1
Supplemental figures with captions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f3c059ffffe7d53a4fe2423565d371
https://doi.org/10.1158/1541-7786.22514250
https://doi.org/10.1158/1541-7786.22514250
Autor:
Jeffrey R. Peterson, Ulrike Rennefahrt, Mauricio J. Reginato, Timothy P. Moran, Kathy Q. Cai, Emmanuelle Nicolas, Christina M. Ferrer, Erik Peter, Alexander Strigun, Tanu Singh, Lauren S. Fink, Alexander Beatty
Table S2. Principal component analysis loadings for plots shown in Figure 1C and Figure 1D, included as separate Excel file.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdecfde950f5495dd703d02f72ff97d
https://doi.org/10.1158/1535-7163.22504557.v1
https://doi.org/10.1158/1535-7163.22504557.v1
Supplemental Figure 6: The number of live and dead cells were counted across 5 separate images per sample; Western blot was performed on total protein harvested from cells grown in 2D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777cdc1a147d14b7487c5614a11aa9bf
https://doi.org/10.1158/1541-7786.22514259
https://doi.org/10.1158/1541-7786.22514259