Infants Younger Than 6 Months Infected With SARS-CoV-2 Show the Highest Respiratory Viral Loads

Autor: Valeria, Ochoa, Fernando Erra, Díaz, Ezequiel, Ramirez, María Clara, Fentini, Mauricio, Carobene, Jorge, Geffner, Lourdes, Arruvito, Federico, Remes Lenicov, Douglas, Vera Aguilar

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The Journal of Infectious Diseases

There is a paucity of reports on the characteristics of SARS-CoV-2 infection in infants, since most studies have grouped infants with older children. We analyzed the viral loads of 45,318 SARS-CoV-2-positive nasopharyngeal swab samples obtained in Bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937692f5a3a0f9c4a1d1ebc589e44b80
https://doi.org/10.1093/infdis/jiab577

T-cell immune responses against Env from CRF12_BF and subtype B HIV-1 show high clade-specificity that can be overridden by multiclade immunizations.

Autor: Daniela C Mónaco, Ana M Rodríguez, María F Pascutti, Mauricio Carobene, Juliana Falivene, Alejandro Gómez, Cynthia Maeto, Gabriela Turk, José L Nájera, Mariano Esteban, M Magdalena Gherardi

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17185 (2011)

BACKGROUND: The extreme genetic diversity of the human immunodeficiency virus type 1 (HIV-1) poses a daunting challenge to the generation of an effective AIDS vaccine. In Argentina, the epidemic is characterized by the high prevalence of infections c

Externí odkaz: https://doaj.org/article/f850e75749c04d53a2030fd57e0af936

Human immunodeficiency virus-1 BF intersubtype recombinant viral protein U second alpha helix plays an important role in viral release and BST-2 degradation

Autor: Mauricio Carobene, Constanza Eleonora Espada, Cristian Ariel de Candia, Gabriel Duette, Horacio Salomón

Publikováno v: Journal of General Virology. 94:758-766

We previously reported a naturally occurring BF intersubtype recombinant viral protein U (Vpu) variant with an augmented capacity to enhance viral replication. Structural analysis of this variant revealed that its transmembrane domain and α-helix I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb70a7f2f788e98b94b9bfa3d66c61eb
https://doi.org/10.1099/vir.0.047746-0

Drug-resistance surveillance among newly HIV-1 diagnosed individuals in Buenos Aires, Argentina

Autor: Dario A. Dilernia, Christian T. Bautista, Horacio Salomón, Marcelo H. Losso, Alejandro M. Gomez, Rubén Marone, Juan Ebenrstejin, Mauricio Carobene, Javier Toibaro, Manuel Gómez-Carrillo, Sandra Pampuro, Leonardo Lourtau

Publikováno v: AIDS. 21:1355-1360

Our objective was to estimate primary resistance in an urban setting in a developing country with a long history of antiretroviral delivery and high coverage levels. We carried out a resistance surveillance study according to WHO HIV-Resistance Guide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f173227a81ee47b3d5aca42672c8c2e0
https://doi.org/10.1097/qad.0b013e3280b07db1

Deciphering How HIV-1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression

Autor: Mauricio Carobene, Gabriela Turk

Publikováno v: EBioMedicine
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
EBioMedicine, Vol 2, Iss 3, Pp 188-189 (2015)

Background Clinicians reported an increasing trend of rapid progression (RP) (AIDS within 3 years of infection) in Cuba. Methods Recently infected patients were prospectively sampled, 52 RP at AIDS diagnosis (AIDS-RP) and 21 without AIDS in the same

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b4ef1f64832f923590c096e1d84263
https://pubmed.ncbi.nlm.nih.gov/26137563