Low miR‐19b‐1‐5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio‐ Cerebrovascular Events in Patients With Acute Coronary Syndrome

Autor: Sandeep Singh, Maurice W. J. de Ronde, Esther E. Creemers, Ingeborg Van der Made, Roelien Meijering, Mark Y. Chan, Sock Hwee Tan, Chee Tang Chin, A. Mark Richards, Richard W. Troughton, Alan Yean Yip Fong, Bryan P. Yan, Sara‐Joan Pinto‐Sietsma

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 2 (2021)

Background Because of a nonresponse to aspirin (aspirin resistance), patients with acute coronary syndrome (ACS) are at increased risk of developing recurrent event. The in vitro platelet function tests have potential limitations, making them unsuita

Externí odkaz: https://doaj.org/article/584c4a0e2e3e48f1875f932652959211

Low miR-19b-1-5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio- Cerebrovascular Events in Patients With Acute Coronary Syndrome

Autor: Bryan P. Yan, Alan Yean Yip Fong, Sandeep Singh, Sara-Joan Pinto-Sietsma, Esther E. Creemers, Chee Tang Chin, Roelien A. M. Meijering, Sock Hwee Tan, A. Mark Richards, Maurice W J de Ronde, Ingeborg van der Made, Mark Y. Chan, Richard W. Troughton

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, 10(2):e017120, 1-9. Wiley-Blackwell

Background Because of a nonresponse to aspirin (aspirin resistance), patients with acute coronary syndrome (ACS) are at increased risk of developing recurrent event. The in vitro platelet function tests have potential limitations, making them unsuita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2672c88fb49c0ca5afc9a8abd735db5
https://pubmed.ncbi.nlm.nih.gov/33441016

Study Design and qPCR Data Analysis Guidelines for Reliable Circulating miRNA Biomarker Experiments: A Review

Autor: Jan M. Ruijter, Esther E. Creemers, Perry D. Moerland, Maurice W J de Ronde, Sara-Joan Pinto-Sietsma

Publikováno v: Clinical Chemistry. 64:1308-1318

BACKGROUND In the past decade, the search for circulating microRNA (miRNA) biomarkers has yielded numerous associations between miRNAs and different types of disease. However, many of these relations could not be replicated in subsequent studies unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfbcd874d9b1fc456cb35da8ce8b69e
https://doi.org/10.1373/clinchem.2017.285288

Prognostic value of circulating microRNAs on heart failure-related morbidity and mortality in two large diverse cohorts of general heart failure patients

Autor: Yigal M. Pinto, Marinus J.C. Eijkemans, Aeilko H. Zwinderman, Josep Lupón, Elisabet Zamora, Nicolaas P.A. Zuithoff, Maurice W J de Ronde, Marta de Antonio, Joost J. Leenders, Antoni Bayes-Genis, Sara-Joan Pinto-Sietsma, David E. Lanfear, Zhen Liu

Publikováno v: European Journal of Heart Failure. 20:67-75

Aims Small studies suggested circulating microRNAs (miRNAs) as biomarkers for heart failure (HF). However, standardized approaches and quality assessment for measuring circulating miRNAs are not uniformly established, and most studies have been small

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef23e7d0bc4e7f11fa01da5f1d2fc777
https://doi.org/10.1002/ejhf.984

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis

Autor: Maurice W J de Ronde, Maayke G.M. Kok, Jan Van den Bossche, Amalia Halliani, Sara-Joan Pinto-Sietsma, Esther E. Creemers, Ingeborg van der Made, Menno P.J. de Winther, Joost C. M. Meijers, Perry D. Moerland, Annette E. Neele

Publikováno v: Atherosclerosis, 263, 377-384. Elsevier Ireland Ltd

Background and aims: The risk of developing cardiovascular disease (CVD) is twice as high among smoking individuals compared to non-smokers. Monocytes are involved in smoking-related atherosclerotic plaque formation. In this study, we investigated wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ed2730d95a730ce46b9f08fd9dbbd3
https://doi.org/10.1016/j.atherosclerosis.2017.03.045