Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maurice Vroemen"'
Publikováno v:
Experimental Neurology. 195:127-139
Gene transfer into multipotent neural progenitor cells (NPC) and stem cells may provide for a cell replacement therapy and allow the delivery of therapeutic proteins into the degenerating or injured nervous system. Previously, murine leukemia virus-b
Autor:
Ulrich Bogdahn, Norbert Weidner, Sebastien Couillard-Despres, Beate Winner, Robert Aigner, Maurice Vroemen, Ludwig Aigner, Hans-Georg Kuhn, Jürgen Winkler, Susanne Schaubeck
Publikováno v:
European Journal of Neuroscience. 21:1-14
Progress in the field of neurogenesis is currently limited by the lack of tools enabling fast and quantitative analysis of neurogenesis in the adult brain. Doublecortin (DCX) has recently been used as a marker for neurogenesis. However, it was not cl
Autor:
F. May, A. Lehmer, T. Mrva, J. Henke, C. Caspers, H. Schwaibold, K. Matiasek, Maurice Vroemen, R. Hartung, W. Erhardt, B. Gänsbacher, Norbert Weidner
Publikováno v:
Journal of Urology. 172:374-377
Dissection of the cavernous nerves eliminates spontaneous erections. We evaluated the ability of Schwann cell seeded nerve guidance tubes to restore erections after bilateral cavernous nerve resection in rats.Sections (5 mm) of the cavernous nerve we
Autor:
Norbert Weidner, G. Uyanik, Frank-Peter Wachs, Johanna Kaesbauer, Sonja Ploetz, Juergen Winkler, Clive N. Svendsen, Ludwig Aigner, Maurice Vroemen, Daniel Wilhelm, Jochen Klucken, Maren Engelhardt, Johanna Tebbing, Hans-Georg Kuhn, Sebastien Couillard-Despres, Claudia Karl
Publikováno v:
Laboratory Investigation. 83:949-962
Neural stem cells (NSCs) from the adult central nervous system are currently being investigated for their potential use in autologous cell replacement strategies. High expansion rates of NSCs in culture are crucial for the generation of a sufficient
Autor:
Jürgen Winkler, H. Georg Kuhn, Jason Brown, Hong Ye, Christiana M. Cooper-Kuhn, Maurice Vroemen, Margaret A. Thompson
Publikováno v:
Molecular and Cellular Neuroscience. 21:312-323
During nervous system development the fate of neural stem cells-whether to undergo proliferation, differentiation, or apoptosis-is controlled by various signals, such as growth factors. Here, we demonstrate that the transcription factor E2F1, which i
Autor:
Norbert Weidner, Boris Schlenker, Rudolf Hartung, Alexander Buchner, Armin Blesch, Peter Gais, Thomas Mrva, Christian Arndt, Florian May, Christian G. Stief, Christiane Caspers, Bernd Gansbacher, T. Brill, Kaspar Matiasek, Maurice Vroemen
Publikováno v:
European urology. 54(5)
Background Schwann cell–seeded guidance tubes have been shown to promote cavernous nerve regeneration, and the local delivery of neurotrophic factors may additionally enhance nerve regenerative capacity. The present study evaluates whether the tran
Autor:
Katharina Pfeifer, Norbert Weidner, Ludwig Aigner, Massimiliano Caioni, Ulrich Bogdahn, Maurice Vroemen
Publikováno v:
Regenerative medicine. 1(2)
Adult neural progenitor cells (NPCs) represent an attractive source for cell-based regenerative strategies in CNS disease. In animal models of spinal cord injury, syngenic adult NPCs, which were isolated from pooled post-mortem CNS tissue and co-tran
Publikováno v:
Cell and tissue research. 327(1)
Adult neural progenitor cells (NPC) co-grafted with fibroblasts replace cystic lesion defects and promote cell-contact-mediated axonal regeneration in the acutely injured spinal cord. Fibroblasts are required as a platform to maintain NPC within the
Autor:
Ulrich Bogdahn, Thomas Weber, Cornelius Faber, Peter Prang, Werner Kunz, Klaus Heckmann, Norbert Weidner, Maurice Vroemen, Rainer Müller, Ahmed Eljaouhari
Appropriate target reinnervation and functional recovery after spinal cord injury depend on longitudinally directed regrowth of transected axons. To assess the capacity to promote directed axon regeneration, alginate-based highly anisotropic capillar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7c4d6d31e4f862b330285189724a26
Publikováno v:
The European journal of neuroscience. 20(7)
Adult neural progenitor cells (NPC) are an attractive source for cell transplantation and neural tissue replacement after central nervous system (CNS) injury. Following transplantation of NPC cell suspensions into the acutely injured rat spinal cord,