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Publikováno v:
Molecular immunology. 31(10)
Wasted mice bear an autosomal recessive mutation ( wst / wst ) that manifests itself in neurologic abnormalities, immunologic deficiency, and faulty DNA repair evident by 21 days of age. The immunodeficiency is characterized by a reduction in the thy
Publikováno v:
Cellular immunology. 130(1)
Mice with the autosomal recessive gene "wasted" (wst/wst) exhibit neurologic disorders, reduced mucosal immune responses, and abnormal DNA repair mechanisms. The wst/wst mouse has been proposed as a murine model for the human disorder ataxia telangie