Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Maurice M. Best"'
Autor:
Charles H. Duncan, Maurice M. Best
Publikováno v:
Journal of Lipid Research, Vol 1, Iss 2, Pp 159-163 (1960)
The effect of the addition of 1 per cent nicotinic acid to the diet of the rat on serum, liver, and carcass cholesterol, and on the incorporation of acetate-1-C14 into cholesterol by the intact animal were studied. The effect of nicotinic acid on abs
Externí odkaz:
https://doaj.org/article/7ec28d5c609140a1b0345c5ffa7ac847
Publikováno v:
Circulation Research. 5:401-404
The presence on carbon-3 of a free hyclroxyl group that may be esterified is a common characteristic of the known sterol inhibitors of cholesterol absorption. The 30-carbon sterols found in wool fat possess such a group, but differ from the previousl
Autor:
Charles H. Duncan, Maurice M. Best
Publikováno v:
Endocrinology. 63:169-176
The biologic activity of l–thyroxine, l–triiodothyronine, and their formic acid analogues, tetraiodothyroformic acid and triiodothyroformic acid have been studied in the rat. By thiouracil-goitre inhibition assay they were found to have the follo
Autor:
Maurice M. Best
Publikováno v:
THE AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 224:308-313
Autor:
Maurice M. Best, Charles H. Duncan
Publikováno v:
American Journal of Physiology-Legacy Content. 194:351-354
Thiouracil (0.5%) was added to the diet of athyreotic rats for a 2-week period and serum and liver cholesterol concentrations compared to those of athyreotic controls. Thiouracil administration resulted in an increase in mean serum cholesterol and a
Publikováno v:
Metabolism. 13:1-7
The mean concentration of cholesterol in the body of the normal male rat fed a balanced laboratory chow was 1.72 mg./Gm. body weight. Hyperthyroidism produced by the daily injection of either L-thyroxine or D-thyroxine resulted in an increase in conc
Autor:
Charles H. Duncan, Maurice M. Best
Publikováno v:
Atherosclerosis. 17:161-166
Clofibrate [ethyl p -chlorophenoxyisobutyrate] and probucol [4,4′-(isopropyl-idenedithio)bis(2,6-di- t -butylphenol)] were fed to male albino rats at a 0.25%. concentration in the diet, the drugs being given both singly and in combination. The two
Autor:
Charles H. Duncan, Maurice M. Best
Publikováno v:
American Journal of Physiology-Legacy Content. 204:505-508
Mevalonic acid-2-C14 was injected intraperitoneally into rats, and the incorporation of the C14 into cholesterol of various tissues determined. A disproportionate incorporation into kidney cholesterol was observed, resulting in a specific activity 55
Autor:
Charles H. Duncan, Maurice M. Best
Publikováno v:
Circulation. 42:859-865
The hypolipidemic activity of the phenolic ether, 2-methyl-2-[p-(1,2,3,4-tetrahydro-1-naphthyl)-phenoxy]-propionic acid (Su-13437, Ciba) has been studied in 10 hypercholesterolemic patients. The patients were studied at 3-week intervals during 30 wee
Publikováno v:
Circulation. 10:201-206
The plant sterol, beta-sitosterol, has been administered to nine subjects on unrestricted diet. A sustained reduction of serum total cholesterol and a lowering of the ratio of cholesterol to lipid phosphorus occurred. Interference by sitosterol with