Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Maurice Gola"'
Publikováno v:
The Journal of Physiology. 587:1461-1479
The intrinsic primary afferent neurons (IPANs) of the guinea pig enteric nervous system express Na(v)1.9 sodium channels that produce a persistent TTX-resistant current having a low activation threshold and slow gating kinetics. These neurons receive
Autor:
Maurice Gola, Joel A. Black, Marcel Crest, Dominique Sage, Patrick Delmas, Stephen G. Waxman, Nadine Clerc, M. Mistry, Francois Rugiero
Publikováno v:
The Journal of Neuroscience. 23:2715-2725
Voltage-gated Na+currents play critical roles in shaping electrogenesis in neurons. Here, we have identified a TTX-resistant Na+current (TTX-RINa) in duodenum myenteric neurons of guinea pig and rat and have sought evidence regarding the molecular id
Autor:
Jérôme Devaux, Evelyne Beraud, Christine Beeton, Marcel Crest, Maurice Gola, Jocelyne Barbaria, Claude Forni
Publikováno v:
NeuroReport. :317-320
The ability of myelin basic protein (MBP)-reactive T cells to induce conduction failure was investigated in vivo and in vitro. With the in vivo model, somatosensory evoked potentials (SEP) were recorded before and during adoptively transferred experi
Publikováno v:
Current Opinion in Pharmacology. 2:657-664
Recent studies have shown that intrinsic primary afferent neurons (IPANs) express a much larger range of ionic currents than non-sensory neurons of the enteric nervous system. These ionic currents can be modulated by neurotransmitters that are synapt
Autor:
Laurence Bulteau, Jean Michel Vierfond, Luis J. V. Galietta, Yvette Mettey, Thierry Métayé, Maurice Gola, Michel Joffre, Cécie Marvingt-Mounir, Bernard Verrier, Michael A. Gray, Valerie Chappe, Malcome M.C. Pereira, Frédéric Becq, Olga Zegarra-Moran, Christian Rogier, Robert L. Dormer, Barry E. Argent, Denis Sarrouilhe, Margaret A. McPherson, Renaud Dérand, Robert Tarran, Catherine Figarella, Marc Merten, Wafa Kammouni
Publikováno v:
Journal of Biological Chemistry. 274:27415-27425
Chloride channels play an important role in the physiology and pathophysiology of epithelia, but their pharmacology is still poorly developed. We have chemically synthesized a series of substituted benzo[c]quinolizinium (MPB) compounds. Among them, 6
Autor:
Nicole Alessandri-Haber, Marcel Crest, François Couraud, Christine Arsac, Christophe Paillart, Maurice Gola
Publikováno v:
The Journal of Physiology. 518:203-214
1 The distribution of Na+ channels and development of excitability were investigated in vitro in purified spinal motoneurones obtained from rat embryos at E14, using electrophysiological, immunocytochemical and autoradiographical methods. 2 One hour
Publikováno v:
Perspectives in Drug Discovery and Design. :333-342
Potassium channels are involved at several stages in inflammatory neuropathies by inducing conduction blocks in demyelinated axons and by taking part in cytokines secretion by activated immunitary cells. Blockers of these channels are therefore poten
Publikováno v:
The Journal of Physiology. 510:387-399
1. A time- and voltage-dependent Na(+)-selective current termed INa,M is activated by muscarinic agonists or splanchnic nerve stimulation in sympathetic neurones of rabbit coeliac and superior mesenteric ganglia. The firing patterns induced by INa,M
Autor:
Bernard Verrier, Jean Michel Vierfond, Maurice Gola, Yvette Mettey, John W. Hanrahan, Valerie Chappe, Frédéric Becq
Publikováno v:
British Journal of Pharmacology. 123:683-693
On the basis of their structure, we compared the ability of 35 xanthine derivatives to activate the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel stably expressed in chinese hamster ovary (CHO) cells using the cell-attac
Autor:
Valérie Frémont, Jurphaas Van Rietschoten, Hervé Darbon, Marcel Crest, Marie-France Martin-Eauclaire, Eric Blanc, Maurice Gola
Publikováno v:
Letters in Peptide Science. 4:305-312
Ca2+-activated K+ channels consist of a large family of membrane proteins, among which two groups have been characterized by electrophysiological criteria, the small conductance (SK) and the large conductance (BK) Ca2+-activated K+ channels. Scorpion