Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Maurice F. Scanlon"'
Autor:
Hemanth Bolusani, Marian Ludgate, Robert G. Newcombe, Neera Agarwal, D. Aled Rees, Maurice F. Scanlon, Sam P. L. Rice
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 94:1966-1972
Context: Patients with Addison’s disease and hypopituitarism have increased mortality, chiefly related to vascular disease. Both diseases are characterized by dehydroepiandrosterone (DHEA) deficiency, yet this is not usually corrected. It is unclea
Publikováno v:
Hormone Research in Paediatrics. 70:80-103
Autor:
T Easter, M. D. Lewis, Juan Pedro López-Siguero, David Neil Cooper, David Stuart Millar, Nieves Díaz-Torrado, Annie M. Procter, Linda Fryklund, John Gregory, Luis Fernando López-Canti, Rafael Espino, Cristóbal-Jorge Del Valle, Vicky Newsway, Maurice F. Scanlon, Martin Horan, Ramón Cañete, Martin Norin, Angels Ulied
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 89:1068-1075
The pituitary-expressed GH1 gene was screened for mutation in a group of 74 children with familial short stature. Two novel mutations were identified: an Ile179Met substitution and a −360A→G promoter variant. The Ile179Met variant was shown to ex
Autor:
John A.H. Wass, Maurice F. Scanlon
In the first section of this volume, we have attempted to bring together some of the papers that reflect exciting new areas of development in relation to neuroendocrine investigation. Very recently, specific nucleotide recognition sequences for thyro
Publikováno v:
Clinical Endocrinology. 59:580-584
Summary objective To test the hypothesis that patients with hyperprolactinaemia due to biologically inactive macroprolactin will not show the characteristically increased dopaminergic inhibition of TSH release seen in patients with microprolactinomas
Publikováno v:
British Journal of Pharmacology. 140:764-772
Activation of adenosine receptors in folliculostellate (FS) cells of the pituitary gland leads to the secretion of IL-6 and vascular endothelial growth factor (VEGF). We investigated the action of adenosine A2 receptor agonists on IL-6 and VEGF secre
Autor:
J. Lewis, Jeffrey S. Davies, Maurice F. Scanlon, S. Dann, Helen A. Lane, L. M. Evans, Peter William Collins, J. C. Smith, Jonathan Goodfellow
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:2152-2156
Although GH deficiency may underlie the increased cardiovascular risk in adult hypopituitarism, other coexisting hormonal deficiencies and/or unphysiological hormone replacement may contribute. l-Deamino-8-d-arginine (DDAVP), when administered parent
Autor:
Michael Krawczak, Martin Horan, T Easter, Elizabeth Crowne, John Gregory, John A. Phillips, Phillip Edwards, Linda Fryklund, David Neil Cooper, Victoria Elizabeth Newsway, Annie M. Procter, Sally J. Davies, M. D. Lewis, Martin Norin, Kim Waldron, Jeremy Kirk, Patricia J. Smith, David Stuart Millar, Maurice F. Scanlon
Publikováno v:
Human Mutation. 21:424-440
Subtle mutations in the growth hormone 1 (GH1) gene have been regarded as a comparatively rare cause of short stature. Such lesions were sought in a group of 41 individuals selected for short stature, reduced height velocity, and bone age delay; a gr
Autor:
J. A. H. Wass, Stephen L. Atkin, G. A. Roberts, M. McConnell, Maurice F. Scanlon, F. Hanna, H. E. Turner, P. E. Harris, P.-M. G. Bouloux, A. B. Atkinson, John S. Bevan, Paul M. Stewart, R. A. James, E. Teasdale, Joanna M. Wardlaw
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:4554-4563
Conventional surgery and radiotherapy for acromegaly have limitations. There are few data on the use of the somatostatin analog octreotide (Oct) as primary medical therapy. An open prospective study of 27 patients with newly diagnosed acromegaly was
Publikováno v:
Endocrinology. 143:2427-2436
A1 and A2 adenosine receptors have been identified in the pituitary gland, but the cell type(s) on which they are located and their effects on pituitary cell growth are not known. Therefore, we analyzed the expression of A1 and A2 receptors in primar