Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maurice Dekker"'
Autor:
Tegan A. Otto, Tessa Bergsma, Maurice Dekker, Sara N. Mouton, Paola Gallardo, Justina C. Wolters, Anton Steen, Patrick R. Onck, Liesbeth M. Veenhoff
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114793- (2024)
Summary: Transport through the nuclear pore complex (NPC) relies on intrinsically disordered FG-nucleoporins (FG-Nups) forming a selective barrier. Away from the NPC, FG-Nups readily form condensates and aggregates, and we address how this behavior i
Externí odkaz:
https://doaj.org/article/e1eeaf9c4b9a47fe8aeb7b056514bfad
Diameter dependence of transport through nuclear pore complex mimics studied using optical nanopores
Publikováno v:
eLife, Vol 12 (2024)
The nuclear pore complex (NPC) regulates the selective transport of large biomolecules through the nuclear envelope. As a model system for nuclear transport, we construct NPC mimics by functionalizing the pore walls of freestanding palladium zero-mod
Externí odkaz:
https://doaj.org/article/aec9fc2e33ae45abbd3bb74801c73fc0
Autor:
Tegan A. Otto, Tessa Bergsma, Maurice Dekker, Sara N. Mouton, Paola Gallardo, Justina C. Wolters, Anton Steen, Patrick R. Onck, Liesbeth M. Veenhoff
Transport through the NPC relies on intrinsically disordered FG-Nups forming a selective barrier. Away from the NPC, FG-Nups readily form condensates and aggregates, and we address how this behavior is surveilled in cells. FG-Nups, including Nsp1, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4c8075721cd6b5363e6c1a11cf7d74
https://doi.org/10.1101/2023.03.31.535084
https://doi.org/10.1101/2023.03.31.535084
Diameter Dependence of Transport through Nuclear Pore Complex Mimics Studied Using Optical Nanopores
Autor:
Nils Klughammer, Anders Barth, Maurice Dekker, Alessio Fragasso, Patrick R. Onck, Cees Dekker
The nuclear pore complex (NPC) regulates the selective transport of large biomolecules through the nuclear envelope. As a model system for nuclear transport, we construct NPC mimics by functionalizing the pore walls of freestanding palladium zero-mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33700002ce01c85d7b5c791c2d9ed1ec
https://doi.org/10.1101/2023.02.18.529008
https://doi.org/10.1101/2023.02.18.529008
The intrinsically disordered FG-Nups in the NPC central channel can undergo liquid-liquid phase sepration (LLPS) into liquid condensates that display NPC-like permeability barrier properties. Here we present LLPS characteristics of each of the disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::489af64d1f8e1dc5c7d9fabce43b51bd
https://doi.org/10.1101/2022.09.20.508740
https://doi.org/10.1101/2022.09.20.508740
Autor:
Anders Barth, Eva Bertosin, Nils Klughammer, Alejandro M. Gonzalez, Eli van der Sluis, Maurice Dekker, Patrick R. Onck, Cees Dekker
Publikováno v:
Biophysical Journal. 122:427a-428a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b9364fb1f36f43c652a614b263877c
https://doi.org/10.1016/j.bpj.2022.11.2314
https://doi.org/10.1016/j.bpj.2022.11.2314
Publikováno v:
Biophysical Journal, 120(3 Suppl. 1), 28A-28A. CELL PRESS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a39d13ee5b83aed536d7c1423a61882
https://hdl.handle.net/11370/c4e6024c-68ab-4d31-a931-8d900150d72b
https://hdl.handle.net/11370/c4e6024c-68ab-4d31-a931-8d900150d72b