Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Maurice Chan"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45798 (2012)
The emergence of benchtop sequencers has made clinical genetic testing using next-generation sequencing more feasible. Ion Torrent's PGM™ is one such benchtop sequencer that shows clinical promise in detecting single nucleotide variations (SNVs) an
Externí odkaz:
https://doaj.org/article/c6ae002a895d448296f7d1d3ccb52186
Autor:
Ann Siew-Gek Lee, Gay Hui Ho, Puay Hoon Tan, Aye Aye Thike, Chow Yin Wong, Hwee Huang Tan, Shen Mo Ji, Chiew Suan Liaw, Maurice Chan
PDF file - 189K, Supplementary Fig. S1: Three components principal component analysis of (a) tissue and (b) serum samples. Breast cancer tumour tissues (a) and serum from breast cancer patients (b) are indicated in red. Adjacent normal tissues (a) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627b38d353155ae6483a1f4eb2c3f060
https://doi.org/10.1158/1078-0432.22445825
https://doi.org/10.1158/1078-0432.22445825
Autor:
Ann Siew-Gek Lee, Gay Hui Ho, Puay Hoon Tan, Aye Aye Thike, Chow Yin Wong, Hwee Huang Tan, Shen Mo Ji, Chiew Suan Liaw, Maurice Chan
Purpose: There is a quest for novel noninvasive diagnostic markers for the detection of breast cancer. The goal of this study is to identify circulating microRNA (miRNA) signatures using a cohort of Asian Chinese patients with breast cancer, and to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d9472b45a682fb99b7a1efbc2b1427
https://doi.org/10.1158/1078-0432.c.6520571.v1
https://doi.org/10.1158/1078-0432.c.6520571.v1
Autor:
Ann Siew-Gek Lee, Gay Hui Ho, Puay Hoon Tan, Aye Aye Thike, Chow Yin Wong, Hwee Huang Tan, Shen Mo Ji, Chiew Suan Liaw, Maurice Chan
PDF file - 127K, Supplementary Table S1: Details of breast cancer patients employed for this study. IDC (NOS), Invasive Ductal Carcinoma (Not Otherwise Specified); DCIS, Ductal Carcinoma In-Situ; ILC, Invasive lobular carcinoma; LN, lymph node status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133372ccb271d799b6aae6c56f578f3e
https://doi.org/10.1158/1078-0432.22445822
https://doi.org/10.1158/1078-0432.22445822
Autor:
Yen-Chia Chen, Po-Hsiang Liao, Yen-Wen Chen, Chia-Ming Chang, Maurice Chan, Deng Fong Chao, Yizhen Lin, Jiahao Chang, Hau Hung, Mengchu Wu, David Hung-Tsang Yen
BackgroundThe traditional diagnosis of sepsis has always been based on microbial blood culture (BC). However, BC suffers from (1) long culture cycle, leading to delay in results, and (2) low diagnostic yields. Metagenomic next-generation sequencing (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eededeb9cb3cc8c44aa555b62821ee2
https://doi.org/10.1101/2023.03.28.23287867
https://doi.org/10.1101/2023.03.28.23287867
Autor:
Maurice Chan, Wan Sia Pang, Thean Yen Tan, Si Huei Tan, Seok Hwee Koo, Boran Jiang, Lily Siew Yong Ng, Qingyao Quek
Publikováno v:
Journal of Microbiological Methods. 153:133-138
Purpose The emergence of antiseptic resistance and/or antiseptic-resistance genes in methicillin-resistant Staphylococcus aureus (MRSA) may result in failure of decolonization treatments. Plasmid-encoded efflux pump genes qacA/B and qacC (smr) confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f85e7943c190e9aa9311df14522e40
https://doi.org/10.1016/j.mimet.2018.09.017
https://doi.org/10.1016/j.mimet.2018.09.017
Publikováno v:
Journal of Clinical Virology
Highlights • Performance of FilmArray, AnyplexII, and Argene platforms was comparable. • Nasopharyngeal swabs in UTM and endotracheal aspirates are suitable sample types. • Test volume is the main determinant for the selection of platform. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc84bfa12209ce19a3346fa162593c5
https://doi.org/10.1016/j.jcv.2018.07.002
https://doi.org/10.1016/j.jcv.2018.07.002
Publikováno v:
Journal of Microbiological Methods. 125:87-90
The Xpert CT/NG is a rapid assay for detection of Neisseria gonorrhoeae and Chlamydia trachomatis. QC materials must be formulated to emulate human specimens, and are prohibitively expensive. A creative, cost-effective QC approach is proposed. The ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dbb67d1d77fecfbc827e0275c51e15
https://doi.org/10.1016/j.mimet.2016.04.010
https://doi.org/10.1016/j.mimet.2016.04.010
Autor:
Arpita Datta, Alan Prem Kumar, Ser Y. Loo, Wanpei Cai, Celestial T. Yap, Kodappully Sivaraman Siveen, Jen Nee Goh, Eun Myoung Shin, Maurice Chan, Peter E. Lobie, Arun Dharmarajan, Ann S.-G. Lee, Wei Ney Yap, Ji E. Kim, Chao Wang
Publikováno v:
Biological Reviews. 91:409-428
A large number of etiological factors and the complexity of breast cancers present challenges for prevention and treatment. Recently, the emergence of microRNAs (miRNAs) as cancer biomarkers has added an extra dimension to the ‘molecular signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf959959d04fb514177b85d6c168e212
https://doi.org/10.1111/brv.12176
https://doi.org/10.1111/brv.12176
Autor:
See Ting Leong, Xin Zhou, Mengchu Wu, Arseny Smirnov, Charlie Lee, Priscilla Lim, Yong Qiang Yeo, Louis Welebob, Hwee Meng Low, Mei Qi Yee, Wen-Huey Lim, Fabianus Mulawadi, Maurice Chan, Wen Huang
Publikováno v:
The journal of applied laboratory medicine. 1(1)
Background We describe a novel system control (SC) implemented in an automated AmpliSeq™-based next-generation sequencing (NGS)2 run that simultaneously acts as (a) an external positive/sensitivity control, (b) a spike-in QC for DNA extraction, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4cb05f6af9afdaa64ff56e63e035c4
https://pubmed.ncbi.nlm.nih.gov/33626812
https://pubmed.ncbi.nlm.nih.gov/33626812