Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Maurice C. Bondurant"'
Publikováno v:
Blood. 105:2168-2174
Most studies of mammalian reticulocyte maturation have used blood reticulocytes.Nascent reticulocytes, as found in bone marrow, have not been available in developmentally synchronized populations. Nascent murine reticulocytes formed in vitro by enucl
Autor:
Alessandro M. Vannucchi, Silvia Linari, Anna Rita Migliaccio, Maurice C. Bondurant, Mark J. Koury, Chyuan-Sheng Lin
Publikováno v:
Journal of Cellular Physiology. 180:390-401
Gata1 is expressed from either one of two alternative promoters, the erythroid (proximal to the AUG) and the testis (distal to the AUG) promoter, both used by hemopoietic cells. To clarify the role of the distal and proximal Gata1 transcripts in eryt
Autor:
Maurice C. Bondurant, Paul A. Gregoli
Publikováno v:
Journal of Cellular Physiology. 178:133-143
Erythropoietin (EP) is required by late stage erythroid progenitor cells to prevent apoptosis. In a previous study (Gregoli and Bondurant, 1997, Blood 90:630–640), it was shown that rapid proteolytic conversion of procaspase 3 to the fully activate
Autor:
Maurice C. Bondurant, Paul A. Gregoli
Publikováno v:
Blood. 90:630-640
Erythropoietin (EP) is required by late-stage erythroid progenitor cells to prevent apoptosis. Several lines of evidence suggest that it is this action of EP that regulates erythrocyte production in vivo. To study the control of apoptosis in mouse an
Publikováno v:
Journal of Cellular Physiology. 168:255-263
The expression of c-myc was analyzed in murine and human erythroblasts throughout their differentiation in vitro into reticulocytes. The murine cells were splenic erythroblasts from animals infected with the anemia strain of Friend virus (FVA cells).
Publikováno v:
Blood. 86:572-580
Stem cell factor (SCF), the ligand for the c-kit tyrosine kinase receptor, markedly stimulates the accumulation of erythroid progenitor cells in vitro. We now report that SCF delays erythroid differentiation among the progeny of individual erythroid
Publikováno v:
Journal of Clinical Investigation. 94:34-43
Erythropoietin (EP), insulin-like growth factor I (IGF-I) and stem cell factor (SCF) each reduce apoptosis of human erythroid progenitor cells. To determine if these growth factors have additional roles in stimulating erythropoiesis, the proliferatio
Publikováno v:
Molecular and Cellular Biology. 14:4183-4192
Erythropoietin (Epo) inhibits apoptosis in murine proerythroblasts infected with the anemia-inducing strain of Friend virus (FVA cells). We have shown that the apoptotic process in FVA cell populations deprived of Epo is asynchronous as a result of a
Autor:
Mark J. Koury, Maurice C. Bondurant, Stephen T. Sawyer, Linda L. Kelley, Stephen T. Koury, Amittha Wickrema
Publikováno v:
Blood. 82:2340-2352
Murine erythroid progenitors infected with the anemia-inducing strain of Friend virus (FVA cells) undergo apoptosis when deprived of erythropoietin (EPO). When cultured with EPO, they survive and complete terminal differentiation. Although cell volum