Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Maurice B. Burg"'
Autor:
Natalia I Dmitrieva, Maurice B Burg
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128870 (2015)
Cardiovascular diseases (CVDs) are a leading health problem worldwide. Epidemiologic studies link high salt intake and conditions predisposing to dehydration such as low water intake, diabetes and old age to increased risk of CVD. Previously, we demo
Externí odkaz:
https://doaj.org/article/7134f2b0f659447b977c08d118ec9e89
Autor:
E. Brad Thompson, Jenna F. DuMond, Shagufta H. Khan, Maurice B. Burg, Joan D. Ferraris, Yi He, Raj Kumar
Publikováno v:
Proc Natl Acad Sci U S A
Nuclear Factor of Activated T cells 5 (NFAT5) is a transcription factor (TF) that mediates protection from adverse effects of hypertonicity by increasing transcription of genes, including those that lead to cellular accumulation of protective organic
Autor:
Natalia I Dmitrieva, Maurice B Burg
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20691 (2011)
Dehydration with aging is attributed to decreased urine concentrating ability and thirst. We further investigated by comparing urine concentration and water balance in 3, 18 and 27 month old mice, consuming equal amounts of water. During water restri
Externí odkaz:
https://doaj.org/article/c6190a33876d496084d503dbcbda42a6
Autor:
Margarita Kunin, Natalia I Dmitrieva, Morgan Gallazzini, Rong-Fong Shen, Guanghui Wang, Maurice B Burg, Joan D Ferraris
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12108 (2010)
Hypertonicity, such as induced by high NaCl, increases the activity of the transcription factor TonEBP/OREBP whose target genes increase osmoprotective organic osmolytes and heat shock proteins.We used mass spectrometry to analyze proteins that coimm
Externí odkaz:
https://doaj.org/article/82ec2d8ea4124b5c8781fe5e5fd5c55b
Publikováno v:
JCI Insight
With increased life expectancy worldwide, there is an urgent need for improving preventive measures that delay the development of age-related degenerative diseases. Here, we report evidence from mouse and human studies that this goal can be achieved
Autor:
Shouguo Gao, Xue Zhang, Koji Eguchi, Yuichiro Izumi, Kevin Ramkissoon, Xujing Wang, Joan D. Ferraris, Maurice B. Burg, Jenna F. DuMond, Masashi Mukoyama
Publikováno v:
Physiological Genomics. 48:290-305
NFAT5 is an osmoregulated transcription factor that particularly increases expression of genes involved in protection against hypertonicity. Transcription factors often contain unstructured regions that bind co-regulatory proteins that are crucial fo
Autor:
Dennis Brown, Chung-Lin Chou, Maurice B. Burg, Jae Wook Lee, Sylvie Breton, Maria Merkulova, Mark A. Knepper, Susan M. Wall, Teodor G. Păunescu, Lihe Chen, Jill W. Verlander, Maria A. Battistone, Anil V. Nair
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Tacitly, Edemir (1) points to an important issue in the interpretation of data from single-cell RNA-sequencing experiments. Any given cell can exist in a variety of regulatory states that are affected both by extracellular signals and the prior histo
Autor:
Maria Merkulova, Jae Wook Lee, Anil V. Nair, Lihe Chen, Chung-Lin Chou, Susan M. Wall, Sylvie Breton, Mark A. Knepper, Jill W. Verlander, Maria A. Battistone, Teodor G. Păunescu, Dennis Brown, Maurice B. Burg
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Prior RNA sequencing (RNA-seq) studies have identified complete transcriptomes for most renal epithelial cell types. The exceptions are the cell types that make up the renal collecting duct, namely intercalated cells (ICs) and principal cells (PCs),
Autor:
J'Neka S. Claxton, Pablo C. Sandoval, Chin-Rang Yang, Viswanathan Raghuram, Kiyoshi Isobe, Maurice B. Burg, Mark A. Knepper, Hyun Jun Jung
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(42)
G protein stimulatory α-subunit (Gαs)-coupled heptahelical receptors regulate cell processes largely through activation of protein kinase A (PKA). To identify signaling processes downstream of PKA, we deleted both PKA catalytic subunits using CRISP
Autor:
Dennis Brown, Sylvie Breton, Anil V. Nair, Jae Wook Lee, Jill W. Verlander, Maria A. Battistone, Maria Merkulova, Mark A. Knepper, Lihe Chen, Susan M. Wall, Chung-Lin Chou, Maurice B. Burg, Teodor G. Păunescu
Prior RNA sequencing (RNA-Seq) studies have identified complete transcriptomes for most renal epithelial cell types. The exceptions are the cell types that make up the renal collecting duct, namely intercalated cells (ICs) and principal cells (PCs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3257de5be5e7f6c177ffcad65632da39