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of 23
pro vyhledávání: '"Maurice B, Hallett"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4254 (2024)
Phagocytosis (and endocytosis) is an unusual cellular process that results in the formation of a novel subcellular organelle, the phagosome. This phagosome contains not only the internalised target of phagocytosis but also the external medium, creati
Externí odkaz:
https://doaj.org/article/7e9197047dd74690ad90de755ae8168e
Autor:
Maurice B. Hallett
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2825 (2023)
Phagocytosis is one of the most polarised of all cellular activities. Both the stimulus (the target for phagocytosis) and the response (its internalisation) are focussed at just one part of the cell. At the locus, and this locus alone, pseudopodia fo
Externí odkaz:
https://doaj.org/article/5848427ca85d4dc892af9509002727eb
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1383 (2019)
Perhaps the most important feature of neutrophils is their ability to rapidly change shape. In the bloodstream, the neutrophils circulate as almost spherical cells, with the ability to deform in order to pass along narrower capillaries. Upon receivin
Externí odkaz:
https://doaj.org/article/bff7860574c34b4cac0f1b7b1b0fac56
Autor:
Maurice B, Hallett
Publikováno v:
Advances in experimental medicine and biology. 1246
Phagocytosis is usually defined as the cellular process by which cells internalise particulate matter larger than about 0.5 μm in diameter. It is an endocytic process, distinct from pinocytosis and macropinocytosis. These latter processes may intern
Publikováno v:
Advances in experimental medicine and biology. 1246
During phagocytosis, there is an apparent expansion of the plasma membrane to accommodate the target within a phagosome. This is accompanied (or driven by) a change in membrane tension. It is proposed that the wrinkled topography of the phagocyte sur
Autor:
Sharon, Dewitt, Maurice B, Hallett
Publikováno v:
Advances in experimental medicine and biology. 1246
Although the cytosolic Ca
Autor:
Maurice B, Hallett
Publikováno v:
Advances in experimental medicine and biology. 1246
Although we know a wealth of detail about the molecular and cell biology of phagocytosis, there are many unsolved mysteries remaining. In this final chapter, some important may be tangential) questions are raised, that the bulk of researchers are not
Publikováno v:
Cell calcium. 92
The construction of a low affinity Ca
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2087
The ability to microinject substances into the cytosol of living neutrophils opens the possibility of manipulating the chemistry within the cell and also of monitoring changes using indicators which otherwise cannot be introduced into the cell. Howev
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2087
The measurement and manipulation of cytosolic free Ca(2+) of neutrophils is crucial for investigating the mechanisms within living neutrophils which generate Ca(2+) signals and the cellular responses triggered by them. Optical methods for this are th