Zobrazeno 1 - 10
of 5 670
pro vyhledávání: '"Maurice B"'
Publikováno v:
Geothermal Energy, Vol 12, Iss 1, Pp 1-31 (2024)
Abstract Multi-objective optimization and CFD simulation are conducted to optimize the design of a multi-borehole ground heat exchanger (GHE) system and assess its long-time performance. The multi-objective optimization is performed to minimize the e
Externí odkaz:
https://doaj.org/article/b02d6c4445354071a35fcb046bc8dc8c
Autor:
Carlijn A. Hoekx, Maaike E. Straat, Maurice B. Bizino, Huub J. vanEyk, Hildebrandus J. Lamb, Johannes W. A. Smit, Ingrid M. Jazet, Saskia C. A. deJager, Mariëtte R. Boon, Borja Martinez‐Tellez
Publikováno v:
Experimental Physiology, Vol 109, Iss 8, Pp 1292-1304 (2024)
Abstract Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists induce weight loss in patients with type 2 diabetes mellitus (T2DM), but the underlying mechanism is unclear. Recently, the mechanism by which metformin induces weight loss could be ex
Externí odkaz:
https://doaj.org/article/480115ade2eb4c9e882a6403f123df23
Autor:
Anish Jain, Hyun Jun Jung, Joseph Aubee, Jahn N. O’Neil, Laila A. Muhammad, Shaza Khan, Karl Thompson, Maurice B. Fluitt, Dexter L. Lee, Carolyn M. Klinge, Syed J. Khundmiri
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1048 (2024)
MicroRNAs (miRNAs) play important roles in the regulation of cellular function and fate via post-transcriptional regulation of gene expression. Although several miRNAs are associated with physiological processes and kidney diseases, not much is known
Externí odkaz:
https://doaj.org/article/53f0e495455647b88d5376bc729b791d
496 Urinary Exosomal MicroRNA as Early Markers of Diabetic Kidney Disease in African American Adults
Autor:
Maurice B. Fluitt, Neal Mohit, Mykaiya Sumling, Baiyee-Ndang Agbor-Baiyee, Kanwal K. Gambhir, Gail Nunlee-Bland, Constance Mere
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 146-147 (2024)
OBJECTIVES/GOALS: This study aimed to characterize urinary exosomal miRNA content in African American adults with diabetic kidney disease. METHODS/STUDY POPULATION: Male and female participants between the ages of 18 and 65 were recruited from the Di
Externí odkaz:
https://doaj.org/article/ebb6557d86294880a543f23cd72a4e47
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300357 (2024)
BackgroundWe investigated the impact of the COVID-19 pandemic on trends of presentation, management and pathology findings in patients who underwent an appendicectomy for suspected acute appendicitis.MethodThe retrospective study reviewed patients (n
Externí odkaz:
https://doaj.org/article/4d0107d9319940a8b77cf48eda714401
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4254 (2024)
Phagocytosis (and endocytosis) is an unusual cellular process that results in the formation of a novel subcellular organelle, the phagosome. This phagosome contains not only the internalised target of phagocytosis but also the external medium, creati
Externí odkaz:
https://doaj.org/article/7e9197047dd74690ad90de755ae8168e
Autor:
Sadaf Ghaderzadeh, Baiyeendang Agbor-Baiyee, Chidera Obiwuma, Neal Mohit, Kanwal K. Gambhir, Carolyn M. Ecelbarger, Maurice B. Fluitt
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 118-118 (2024)
OBJECTIVES/GOALS: Diabetic Kidney Disease (DKD) is a common diabetes complication, often linked to end-stage renal disease in the United States (US). While autophagy and miRNAs are pivotal, miR-451’s specific role remains understudied. Our study ex
Externí odkaz:
https://doaj.org/article/aff846a53b054fa69ffce73d31a11d9d
Autor:
Ashleigh C. Hamilton, Finian J. Bannon, Philip D. Dunne, Jacqueline James, Stephen McQuaid, Ronan T. Gray, Manuel Salto-Tellez, Chris R. Cardwell, Maurice B. Loughrey, Helen G. Coleman
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 3, Pp 347-359 (2023)
Background and Aims: The observed increase in the incidence of early-onset colorectal cancer (EOCRC) is being driven by sporadic cases, but the molecular characteristics of these tumors are not fully understood. Our objective was to investigate the p
Externí odkaz:
https://doaj.org/article/8d691786c5d14cfba3e309cbd980f469
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gundaz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It remains critical to identify colorectal cancers (CRC) that will disseminate as early as possible. Here, the authors identify CRC tumours that are aggressive and prone to early dissemination, characterised by epithelial TGFβ and growth-factor sign
Externí odkaz:
https://doaj.org/article/685f337608c24440b7e084866104173a
Autor:
Lushun Yuan, Aswin Verhoeven, Niek Blomberg, Huub J. van Eyk, Maurice B. Bizino, Patrick C. N. Rensen, Ingrid M. Jazet, Hildo J. Lamb, Ton J. Rabelink, Martin Giera, Bernard M. van den Berg
Publikováno v:
Metabolites, Vol 14, Iss 1, p 33 (2024)
Type 2 diabetes mellitus (T2DM) poses a higher risk for complications in South Asian individuals compared to other ethnic groups. To shed light on potential mediating factors, we investigated lipidomic changes in plasma of Dutch South Asians (DSA) an
Externí odkaz:
https://doaj.org/article/ad85c4ff28364256bcca523ac38df8bc