Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche

Autor: Sophia Beng Hui Lim, Shang Wei, Andy Hee-Meng Tan, Maurice A. M. van Steensel, Xinhong Lim

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Abstract Niche cells are widely known to regulate stem/progenitor cells in many mammalian tissues. In the hair, dermal papilla niche cells are well accepted to regulate hair stem/progenitor cells. However, how niche cells themselves are maintained is

Externí odkaz: https://doaj.org/article/f61eece7eaf44375b893ba27101645a2

Author Correction: Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche

Autor: Sophia Beng Hui Lim, Shang Wei, Andy Hee-Meng Tan, Maurice A. M. van Steensel, Xinhong Lim

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)

Externí odkaz: https://doaj.org/article/2042fa72db0f44698267ec3b03109a15

Familial multiple discoid fibromas is linked to a locus on chromosome 5 including the FNIP1 gene

Autor: Irma van de Beek, Iris E. Glykofridis, Michael W. T. Tanck, Monique N. H. Luijten, Theo M. Starink, Jesper A. Balk, Paul C. Johannesma, Eric Hennekam, Maurice J. B. van den Hoff, Quinn D. Gunst, Johan J. P. Gille, Abeltje M. Polstra, Pieter E. Postmus, Maurice A. M. van Steensel, Alex V. Postma, Rob M. F. Wolthuis, Fred H. Menko, Arjan C. Houweling, Quinten Waisfisz

Publikováno v: van de Beek, I, Glykofridis, I E, Tanck, M W T, Luijten, M N H, Starink, T M, Balk, J A, Johannesma, P C, Hennekam, E, van den Hoff, M J B, Gunst, Q D, Gille, J J P, Polstra, A M, Postmus, P E, van Steensel, M A M, Postma, A V, Wolthuis, R M F, Menko, F H, Houweling, A C & Waisfisz, Q 2023, ' Familial multiple discoid fibromas is linked to a locus on chromosome 5 including the FNIP1 gene ', Journal of human genetics, vol. 68, no. 4, pp. 273-279 . https://doi.org/10.1038/s10038-022-01113-1
Journal of human genetics. Nature Publishing Group
Journal of human genetics, 68(4), 273-279. Nature Publishing Group

Previously, we reported a series of families presenting with trichodiscomas, inherited in an autosomal dominant pattern. The phenotype was named familial multiple discoid fibromas (FMDF). The genetic cause of FMDF remained unknown so far. Trichodisco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2dc04d649ec5fe2082f5e11c601c87
http://www.scopus.com/inward/record.url?scp=85145610461&partnerID=8YFLogxK

Immunohistochemical analysis of the mechanistic target of rapamycin and hypoxia signalling pathways in basal cell carcinoma and trichoepithelioma.

Autor: Tjinta Brinkhuizen, Chantal A H Weijzen, Jonathan Eben, Monique R Thissen, Ariënne M van Marion, Björn G Lohman, Véronique J L Winnepenninckx, Patty J Nelemans, Maurice A M van Steensel

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e106427 (2014)

BackgroundBasal cell carcinoma (BCC) is the most common cancer in Caucasians. Trichoepithelioma (TE) is a benign neoplasm that strongly resembles BCC. Both are hair follicle (HF) tumours. HFs are hypoxic microenvironments, therefore we hypothesized t

Externí odkaz: https://doaj.org/article/074f8369880a490fa68e9e6722d21a80

Epigenetic changes in Basal Cell Carcinoma affect SHH and WNT signaling components.

Autor: Tjinta Brinkhuizen, Karin van den Hurk, Véronique J L Winnepenninckx, Joep P de Hoon, Ariënne M van Marion, Jürgen Veeck, Manon van Engeland, Maurice A M van Steensel

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51710 (2012)

BackgroundThe genetic background of Basal Cell Carcinoma (BCC) has been studied extensively, while its epigenetic makeup has received comparatively little attention. Epigenetic alterations such as promoter hypermethylation silence tumor suppressor ge

Externí odkaz: https://doaj.org/article/c538522c95144ee4a3d887164b480cdd