Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Maurice Barcos"'
Autor:
Andrew Hyland, Maria R. Baer, Sheila N.J. Sait, Meir Wetzler, AnneMarie W. Block, Maurice Barcos, Eunice S. Wang, Laurie A. Ford, Andrea S. Licht, Hun Ju Lee
Publikováno v:
Annals of Hematology. 91:359-365
Obesity adversely affects outcome in pediatric acute lymphocytic leukemia and acute myeloid leukemia (AML). We asked if obesity, measured by body mass index (BMI), affected outcome in 329 adult AML patients treated with high-dose cytarabine and idaru
Autor:
Laurie A. Ford, Maria R. Baer, Norma J. Nowak, Chris Andrews, S. M. Tighe, Maurice Barcos, AnneMarie W. Block, Meir Wetzler, Eunice S. Wang, Heinz Baumann, Sheila N.J. Sait
Publikováno v:
Cancer. 117:4831-4868
BACKGROUND: Constitutive activation of signal transducer and activator of transcription-3 (STAT3) was detected in blasts from approximately 50% of patients with acute myeloid leukemia (AML) and was correlated with an adverse outcome. In vitro treatme
Autor:
Asher Chanan-Khan, Mehul Patel, Myron S. Czuczman, Alice Mohr, Kena C. Miller, Zale P. Bernstein, Taimur Sher, Laurie Musial, Swaminathan Padmanabhan, Maurice Barcos, Sikander Ailawadhi, Kelvin Lee, Dan M. Iancu, Jihnhee Yu
Publikováno v:
Leukemia & Lymphoma. 50:1096-1101
Novel agents have demonstrated enhanced efficacy when combined with other antimyeloma agents especially dexamethasone. The steroid doses employed in myeloma regimens are often poorly tolerated. Therefore, in a phase II clinical trial we investigated
Autor:
Maria R. Baer, Cecilia Arana-Yi, Sheila N.J. Sait, Laurie A. Ford, Maurice Barcos, AnneMarie W. Block
Publikováno v:
Leukemia Research. 32:1043-1048
Therapy-related myelodysplastic syndrome and acute myeloid leukemia (t-MDS/t-AML) have been reported only rarely following treatment of AML. We report five patients treated for de novo AML who developed t-MDS/t-AML, all with chromosome 7 abnormalitie
Autor:
Leonard D. Shultz, Thomas F. Conway, Hiroshi Takita, Gregory F Sonnenberg, Michelle R. Simpson-Abelson, Sandra J. Yokota, Maurice Barcos, Richard B. Bankert, Raymond J. Kelleher
Publikováno v:
The Journal of Immunology. 180:7009-7018
Non-disrupted pieces of primary human lung tumor implanted into NOD-scid IL2Rγnull mice consistently result in successful xenografts in which tissue architecture, including tumor-associated leukocytes, stromal fibroblasts, and tumor cells are preser
Autor:
Sheila N.J. Sait, Meyer R. Heyman, Manpreet K. Chadha, Bhuvaneswari Ramkumar, Maria R. Baer, Maurice Barcos
Publikováno v:
Cancer Genetics and Cytogenetics. 182:126-129
Mitoxantrone is a DNA-topoisomerase 2 inhibitor used as a single agent for treatment of relapsing-remitting or progressive multiple sclerosis (MS). We present here two patients treated with mitoxantrone for MS who subsequently developed acute promyel
Autor:
Attaphol Pawarode, Sheila N.J. Sait, Maurice Barcos, Alain Nganga, Lionel J. Coignet, Maria R. Baer
Publikováno v:
Leukemia Research. 31:1589-1592
The BCR/ABL tyrosine kinase inhibitor imatinib mesylate produces a high rate of cytogenetic responses in patients with Philadelphia (Ph)-positive chronic myeloid leukemia (CML), but secondary clonal chromosome abnormalities may develop in Ph-negative
Autor:
Sheila N.J. Sait, Petr Starostik, Eunice S. Wang, Maurice Barcos, Meir Wetzler, Ahmed Abdelhalim, AnneMarie W. Block
Publikováno v:
Leukemia & Lymphoma. 48:1053-1056
Dasatinib (DA, Sprycel,® Bristol-Myers Squibb) is an oral tyrosine kinase inhibitor indicated for treatment of patients with chronic myelogenous leukemia and Philadelphia chromosome-positive (Ph+) ...
Autor:
Bruce A. Peterson, Jeffrey Johnson, Margaret A. Shipp, Maurice Barcos, Jon P. Gockerman, George P. Canellos, null For the Cancer and Leukemia Group B
Publikováno v:
Leukemia & Lymphoma. 48:870-880
Cyclophosphamide and doxorubicin, two important drugs in the treatment of lymphoma, exhibit a relationship between dose and fractional cell kill, and because of their toxicity profiles, they are candidates for significant dose escalation. We performe
Publikováno v:
Cancer Genetics and Cytogenetics. 167:155-160
A growing body of literature reports therapy-related myelodysplastic syndrome (t-MDS) and acute myeloid leukemia (t-AML) in patients treated successfully for acute promyelocytic leukemia (APL). We report a t-MDS with an isochromosome 1q as a sole abn