Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis

Autor: Laurianne Besse, Caroline J. Sheeba, Mark Holt, Maurice Labuhn, Susan Wilde, Eleanor Feneck, Donald Bell, Ania Kucharska, Malcolm P.O. Logan

Publikováno v: Cell Reports, Vol 30, Iss 10, Pp 3552-3565.e6 (2020)

Summary: Although the factors regulating muscle cell differentiation are well described, we know very little about how differentiating muscle fibers are organized into individual muscle tissue bundles. Disruption of these processes leads to muscle hy

Externí odkaz: https://doaj.org/article/bdc96bfff9ce425ab6c893d6f182bdba

RUNX1 isoform disequilibrium promotes the development of trisomy 21 associated myeloid leukemia

Autor: Sofia, Gialesaki, Daniela, Bräuer-Hartmann, Hasan, Issa, Raj, Bhayadia, Oriol, Alejo-Valle, Lonneke, Verboon, Anna-Lena, Schmell, Stephanie, Laszig, Eniko Melinda, Regenyi, Konstantin, Schuschel, Maurice, Labuhn, Michelle, Ng, Robert, Winkler, Christian, Ihling, Andrea, Sinz, Markus, Glaß, Stefan, Hüttelmaier, Sören, Matzk, Lena, Schmid, Farina Josepha, Strüwe, Sofie-Katrin, Kadel, Dirk, Reinhardt, Marie-Laure, Yaspo, Dirk, Heckl, Jan-Henning, Klusmann

Publikováno v: Blood

Gain of chromosome 21 (Hsa21) is among the most frequent aneuploidies in leukemia. However, it remains unclear how partial or complete amplifications of Hsa21 promote leukemogenesis and why children with Down syndrome (i.e. trisomy 21) are particular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e032a4734dffe692b74a5e5a2e423759
https://hdl.handle.net/21.11116/0000-000C-6D6E-021.11116/0000-000C-6D70-C

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies

Autor: Daniel Todt, Alice C. McHardy, Frank Klawonn, Dorothea Bankwitz, Mandy Doepke, Thomas Pietschmann, Markus Cornberg, Tanvi Khera, Patrick Behrendt, Akash Bahai, Florian Klein, Leona Dold, Thomas Krey, Corinne Ginkel, Luisa J Ströh, Maurice Labuhn

Publikováno v: Gut
England

ObjectiveNeutralising antibodies are key effectors of infection-induced and vaccine-induced immunity. Quantification of antibodies’ breadth and potency is critical for understanding the mechanisms of protection and for prioritisation of vaccines. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00fb6348d405a36d92e514c3936c636
https://doi.org/10.1136/gutjnl-2020-321190

Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis

Autor: Caroline J. Sheeba, Laurianne Besse, Malcolm Logan, Maurice Labuhn, Susan Wilde, Donald M. Bell, Ania Kucharska, Eleanor Feneck, Mark R. Holt

Publikováno v: Besse, L, Sheeba, C J, Holt, M, Labuhn, M, Wilde, S, Feneck, E, Bell, D, Kucharska, A & Logan, M P O 2020, ' Individual Limb Muscle Bundles Are Formed through Progressive Steps Orchestrated by Adjacent Connective Tissue Cells during Primary Myogenesis ', Cell Reports, vol. 30, no. 10, pp. 3552-3565.e6 . https://doi.org/10.1016/j.celrep.2020.02.037
Cell Reports
Cell Reports, Vol 30, Iss 10, Pp 3552-3565.e6 (2020)

Summary Although the factors regulating muscle cell differentiation are well described, we know very little about how differentiating muscle fibers are organized into individual muscle tissue bundles. Disruption of these processes leads to muscle hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c9766cc673d42c281e3b9e27f16d08
https://kclpure.kcl.ac.uk/en/publications/b2616459-e6c4-4720-9b97-e2760496c35e

Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter

Autor: Mark-Oliver Trowe, Anna-Carina Weiss, Tobias Bohnenpoll, Timo H. Lüdtke, Maurice Labuhn, Andreas Kispert

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports

The differentiated cell types of the mature ureter arise from the distal ureteric bud epithelium and its surrounding mesenchyme. Uncommitted epithelial cells first become intermediate cells from which both basal and superficial cells develop. Mesench

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7629ef1e83c92f89f8a8b7d729e5ce1b
http://link.springer.com/article/10.1038/s41598-017-14790-2