Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator

Autor: Alain Beley, Stéphane Savary, Françoise Cadepond, Sabrina Leclercq, Stéphane Fourcade, Maurice Bugaut, Pascal G.P. Martin, Maria Rita Lecca, Thierry Pineau, Nathalie Bertrand, Catherine Gondcaille, Dirk De Craemer, Marianne Depreter, Sandrine Duclos, Frank Roels, Martine El-Etr

Publikováno v: The Journal of Cell Biology
JOURNAL OF CELL BIOLOGY
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2005, 169 (1), pp.93-104. ⟨10.1083/jcb.200501036⟩

X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disease due to mutations in the ABCD1 (ALD) gene, encoding a peroxisomal ATP-binding cassette transporter (ALDP). Overexpression of adrenoleukodystrophy-related protein, an ALDP homologue encod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25aa07885c579bd3fd92d3f0f9c7e67b
http://europepmc.org/articles/PMC2171887

Expression of peroxisome proliferator-activated receptors alpha and gamma in differentiating human colon carcinoma Caco-2 cells

Autor: Michel Dauça, Cécile Huin, Renée Hatier, François Plénat, Laurent Antunes, Marc Bentejac, Hervé Schohn, Maurice Bugaut

Publikováno v: Biology of the Cell. 94:15-27

The expression of peroxisome proliferator-activated receptors alpha (PPARalpha) and gamma (PPARgamma) was studied in the human adenocarcinoma Caco-2 cells induced to differentiate by long term culture (15 days). The differentiation of Caco-2 cells wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f1652cfab79a399ffeb82adf7059b6
https://doi.org/10.1016/s0248-4900(01)01178-9

The mouse gene encoding the peroxisomal membrane protein 1-like protein (PXMP1-L): cDNA cloning, genomic organization and comparative expression studies1

Autor: Adelbert A. Roscher, Maurice Bugaut, Stefan Kammerer, Andreas Holzinger, Sabrina Albet, Ania C. Muntau, Peter U. Mayerhofer

Publikováno v: FEBS Letters. 433:179-183

PXMP1-L (synonyms: PMP69, P70R) is a peroxisomal protein that belongs to the ABC-transporter superfamily. Its closest homolog is the peroxisomal membrane protein 1 (PMP70). We have cloned the mouse PXMP1-L gene. It encodes a 606 amino acid protein. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8337f6883082eaa6a1061d29c8c5655
https://doi.org/10.1016/s0014-5793(98)00873-4

Pharmacological induction of redundant genes for a therapy of X-ALD: phenylbutyrate and other compounds

Autor: Maurice, Bugaut, Stephane, Fourcade, Catherine, Gondcaille, Fabien, Gueugnon, Marianne, Depreter, Frank, Roels, Angela, Netik, Johannes, Berger, Pascal, Martin, Thierry, Pineau, Francoise, Cadepond, Martine, El Etr, Stephane, Savary

Publikováno v: Advances in experimental medicine and biology. 544

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bd68fbe3cbb755a6d04fc4bfafecc45
https://pubmed.ncbi.nlm.nih.gov/14713242

Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2)

Autor: Martine El Etr, Françoise Cadepond, Maurice Bugaut, Stéphane Fourcade, Stéphane Savary, Brunhilde Molzer, Angela Netik, Johannes Berger, Catherine Gondcaille

Publikováno v: Molecular pharmacology. 63(6)

X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disorder associated with impaired very-long-chain fatty-acid (VLCFA) beta-oxidation caused by mutations in the ABCD1 (ALD) gene that encodes a peroxisomal membrane ABC transporter. ABCD2 (ALDR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c5a0adabbe4d82136eae7b0b97b8c
https://pubmed.ncbi.nlm.nih.gov/12761339